Abstract: A method of isolating/treating a particulate target using an apparatus comprising at least a capillary comprising a tip orifice and an internal cavity comprising a treatment liquid, a positioning element capable of positioning the tip orifice of the capillary, and a discharging/drawing element capable of causing a discharge of treatment liquid from the capillary and causing a drawing of treatment liquid into the capillary. The method comprises the steps of (1) locating the particulate target to be isolated and treated, (2) positioning the tip orifice such that the tip orifice comes in proximity to the particulate target, using the positioning element, (3) discharging a volume of treatment liquid to enclose the particulate target in the treatment liquid, (4) drawing the particulate target enclosed in the treatment liquid into the internal cavity of the capillary, and (5) treating the particulate target within the internal cavity of the capillary comprising the treatment liquid.

Abstract: A method for three-dimensional microdissection for separating defined structures in the sub-millimeter range by cold laser ablation or multi-photon absorption, whereby exposure of the structures to be separated is performed using directional information in all spatial directions. Also, a 3D microdissection system for separating defined, three-dimensional structures from a sample, having: a control unit (5); an ablation chamber (1) with a sample holder, on which the sample to be processed is mounted and which is movable along a linear axis V and rotatable about a rotary axis R. The sample holder has positioning devices connected to the control unit. The positioning devices move the sample holder along another linear axis H and rotate it about rotary axis R, and a laser device (6) is introduced into the ablation chamber at least partially through a laser window (3) in the ablation chamber.

Abstract: Methods and devices for cutting and collecting dissected specimens are described herein.

Abstract: A dish for cell cultivation and microscopy is provided, comprising a ring and an outer ridge upwardly and axially protruding therefrom, wherein the ring is covered at its bottom side with a transparent membrane and, thus, forms a recess delimited by the inner side of the ring and the membrane, characterized in that the recess is filled with an adhesive filling. Alternatively, a dish for cell cultivation and microscopy is provided, comprising a base and an outer ridge protruding upwardly and axially at its rim, wherein the base and the outer ridge are made of a transparent plastic, the base together with the inner side of the outer ridge forms a recess filled with an adhesive filling, and the thickness of the base and the filling together is less than about 1 mm.

Abstract: Methods and devices for cutting and collecting dissected specimens are described herein.

Abstract: A dish for cell cultivation and microscopy is provided, comprising a ring and an outer ridge upwardly and axially protruding therefrom, wherein the ring is covered at its bottom side with a transparent membrane and, thus, forms a recess delimited by the inner side of the ring and the membrane, characterized in that the recess is filled with an adhesive filling. Alternatively, a dish for cell cultivation and microscopy is provided, comprising a base and an outer ridge protruding upwardly and axially at its rim, wherein the base and the outer ridge are made of a transparent plastic, the base together with the inner side of the outer ridge forms a recess filled with an adhesive filling, and the thickness of the base and the filling together is less than about 1 mm.

Abstract: Methods and devices for cutting and collecting dissected specimens are described herein.

Abstract: A method for three-dimensional microdissection for the separation of defined structures in the sub-millimeter range by means of cold laser ablation or by means of multi-photon absorption, whereby exposure of the structures to be separated is performed using directional information in all spatial directions.

Abstract: Methods and devices for cutting and collecting dissected specimens are described herein.