Patents by Inventor Stefan Oscarson

Stefan Oscarson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DITHIOLSACCHARIDE MUCOLYTIC AGENTS AND USES THEREOF
    Publication number: 20250092076
    Abstract: There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a dithiolsaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
    Type: Application
    Filed: November 26, 2024
    Publication date: March 20, 2025
    Inventors: Stefan Oscarson, John Vincent Fahy, Irina Gitlin, Wilfred Raymond
  • DITHIOLSACCHARIDE MUCOLYTIC AGENTS AND USES THEREOF
    Publication number: 20250092077
    Abstract: There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a dithiolsaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
    Type: Application
    Filed: November 26, 2024
    Publication date: March 20, 2025
    Inventors: Stefan Oscarson, John Vincent Fahy, Irina Gitlin, Wilfred Raymond
  • Dithiolsaccharide mucolytic agents and uses thereof
    Patent number: 12187762
    Abstract: There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a dithiolsaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: January 7, 2025
    Assignees: The Regents of the University of California, University College Dublin
    Inventors: Stefan Oscarson, John Vincent Fahy, Irina Gitlin, Wilfred Raymond
  • Immobilised biological entities
    Patent number: 11850334
    Abstract: There is provided inter alia an anticoagulant surface which surface has covalently bound thereto a plurality of fragments of heparin, wherein said fragments consist of 5-18 saccharide units and at least some of said plurality of fragments comprise polysaccharide sequence A, which surface catalyses the inhibition of FIIa and FXa by AT.
    Type: Grant
    Filed: October 3, 2019
    Date of Patent: December 26, 2023
    Assignee: Carmeda AB
    Inventors: Dagmar Pikas, Johan Riesenfeld, Karin Leontein, Eva Koch, Stefan Oscarson
  • Phosphorylated heptose compounds: process for their preparation and use
    Patent number: 11707519
    Abstract: Processes for the preparation of phosphorylated heptose compounds are provided. Embodiments of the invention relate to the chemical synthesis of heptopyranose phosphate compounds. Also, embodiments of the invention relate to the use of compounds according to the invention in modulating an immune response in a subject.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: July 25, 2023
    Assignees: UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, NATIONAL RESEARCH COUNCIL OF CANADA
    Inventors: Andrew Cox, Janelle Sauvageau, Stefan Oscarson, Lorenzo Guazzelli
  • THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION
    Publication number: 20230181607
    Abstract: Disclosed herein, inter alia, are methods of using thiosaccharide compounds for treating coronavirus infection.
    Type: Application
    Filed: May 11, 2021
    Publication date: June 15, 2023
    Applicants: The University of the Regents of California, University College Dublin
    Inventors: John Vincent Fahy, Irina Gitlin, Wilfred Raymond, Stefan Oscarson
  • IMMOBILISED BIOLOGICAL ENTITIES
    Publication number: 20210379253
    Abstract: There is provided inter alia an anticoagulant surface which surface has covalently bound thereto a plurality of fragments of heparin, wherein said fragments consist of 5-18 saccharide units and at least some of said plurality of fragments comprise polysaccharide sequence A, which surface catalyses the inhibition of FIIa and FXa by AT.
    Type: Application
    Filed: October 3, 2019
    Publication date: December 9, 2021
    Inventors: Dagmar Pikas, Johan Riesenfeld, Karin Leontein, Eva Koch, Stefan Oscarson
  • DITHIOLSACCHARIDE MUCOLYTIC AGENTS AND USES THEREOF
    Publication number: 20210230202
    Abstract: There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a dithiolsaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
    Type: Application
    Filed: September 10, 2019
    Publication date: July 29, 2021
    Inventors: Stefan Oscarson, John Vincent Fahy, Irina Gitlin, Wilfred Raymond
  • Thiosaccharide mucolytic agents
    Patent number: 11021506
    Abstract: There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a thiosaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: June 1, 2021
    Assignees: The Regents of the University of California, University College Dublin
    Inventors: Stefan Oscarson, John Vincent Fahy, Shaopeng Yuan, Stephen Carrington
  • PHOSPHORYLATED HEPTOSE COMPOUNDS: PROCESS FOR THEIR PREPARATION AND USE
    Publication number: 20200215186
    Abstract: Processes for the preparation of phosphorylated heptose compounds are provided. Embodiments of the invention relate to the chemical synthesis of heptopyranose phosphate compounds. Also, embodiments of the invention relate to the use of compounds according to the invention in modulating an immune response in a subject.
    Type: Application
    Filed: May 11, 2018
    Publication date: July 9, 2020
    Applicants: NATIONAL RESEARCH COUNCIL OF CANADA, UNIVERSITY COLLEGE DUBLIN
    Inventors: Andrew COX, Janelle SAUVAGEAU, Stefan OSCARSON, Lorenzo GUAZZELLI
  • THIOSCCHARIDE MUCOLYTIC AGENTS
    Publication number: 20200102340
    Abstract: There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a thiosaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
    Type: Application
    Filed: November 22, 2019
    Publication date: April 2, 2020
    Inventors: Stefan OSCARSON, John Vincent FAHY, Shaopeng YUAN, Stephen CARRINGTON
  • Thiosaccharide mucolytic agents
    Patent number: 10526359
    Abstract: There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a thiosaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: January 7, 2020
    Assignees: The Regents of the University of California, University College Dublin
    Inventors: Stefan Oscarson, John Vincent Fahy, Shaopeng Yuan, Stephen Carrington
  • IMMOBILISED BIOLOGICAL ENTITIES
    Publication number: 20180326118
    Abstract: There is described inter alia a medical device having a surface which comprises a coating layer, said coating layer being a biocompatible composition comprising an entity capable of interacting with mammalian blood to prevent coagulation or thrombus formation, which entity is covalently attached to said surface through a link comprising a 1,2,3-triazole.
    Type: Application
    Filed: July 23, 2018
    Publication date: November 15, 2018
    Applicant: Carmeda AB
    Inventors: Stefan Oscarson, Martina Lahmann, Karin Leontein, Robert Vestberg
  • Immobilised biological entities
    Patent number: 10064978
    Abstract: There is described inter alia a medical device having a surface which comprises a coating layer, said coating layer being a biocompatible composition comprising an entity capable of interacting with mammalian blood to prevent coagulation or thrombus formation, which entity is covalently attached to said surface through a link comprising a 1,2,3-triazole.
    Type: Grant
    Filed: September 19, 2014
    Date of Patent: September 4, 2018
    Assignee: Carmeda AB
    Inventors: Stefan Oscarson, Martina Lahmann, Karin Leontein, Robert Vestberg
  • THIOSACCHARIDE MUCOLYTIC AGENTS
    Publication number: 20180111955
    Abstract: There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a thiosaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
    Type: Application
    Filed: November 27, 2017
    Publication date: April 26, 2018
    Inventors: Stefan Oscarson, John Vincent Fahy, Shaopeng Yuan, Stephen Carrington
  • Thiosaccharide mucolytic agents
    Patent number: 9856283
    Abstract: There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a thiosaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: January 2, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Stefan Oscarson, John Vincent Fahy, Shaopeng Yuan, Stephen Carrington
  • THIOSACCHARIDE MUCOLYTIC AGENTS
    Publication number: 20160060284
    Abstract: There are provided, inter alia, methods for decreasing mucus elasticity or decreasing mucus viscosity in a subject in need thereof, the methods including administering to the subject an effective amount of a thiosaccharide mucolytic agent, and compounds and pharmaceutical compositions useful for the methods.
    Type: Application
    Filed: September 8, 2015
    Publication date: March 3, 2016
    Inventors: Stefan Oscarson, John Vincent Fahy, Shaopeng Yuan, Stephen Carrington
  • Immobilised biological entities
    Patent number: 8992963
    Abstract: There is described inter alia a medical device having a surface which comprises a coating layer, said coating layer being a biocompatible composition comprising an entity capable of interacting with mammalian blood to prevent coagulation or thrombus formation, which entity is covalently attached to said surface through a link comprising a 1,2,3-triazole.
    Type: Grant
    Filed: September 15, 2009
    Date of Patent: March 31, 2015
    Assignee: Carmeda AB
    Inventors: Stefan Oscarson, Martina Lahmann, Karin Leontein, Robert Vestberg
  • IMMOBILISED BIOLOGICAL ENTITIES
    Publication number: 20150045508
    Abstract: There is described inter alia a medical device having a surface which comprises a coating layer, said coating layer being a biocompatible composition comprising an entity capable of interacting with mammalian blood to prevent coagulation or thrombus formation, which entity is covalently attached to said surface through a link comprising a 1,2,3-triazole.
    Type: Application
    Filed: September 19, 2014
    Publication date: February 12, 2015
    Inventors: Stefan Oscarson, Martina Lahmann, Karin Leontein, Robert Vestberg
  • Immunogens for meningitidis-A vaccines
    Patent number: 8062641
    Abstract: An oligosaccharide useful for a Meningitidis A vaccine contains a first mannose unit having a spacer in the alpha configuration at C-1, which spacer is capable of conjugating to a protein, and which is connected to a second mannose unit through a 1,6-linkage which connects C-6 of the first unit to C-1 of the second unit, wherein the 1,6-linkage comprises a phosphonate. Related methods of making such compounds, analogous compounds, or intermediates thereof are also disclosed.
    Type: Grant
    Filed: May 8, 2006
    Date of Patent: November 22, 2011
    Assignees: Novartis AG
    Inventors: Stefan Oscarson, Peter Teodorovic, Paolo Costantino