Abstract: Benzodiazepine derivatives of formula (Ie) wherein one R1 and R2 is a benzodiazepinyl-containing group of formula (II) in which R8 is H or halo; the other of R1 and R2 is a group Z selected from H, C3-C6 cycloalkyl, halo, —NHR9, benzyl, phenyl, 4- to 10-membered heterocyclyl and 4- to 10-membered heteroaryl, wherein phenyl, heterocyclyl and heteroaryl are unsubstituted or substituted by one or two substituents selected from 4- to 10-membered heterocyclyl which is unsubstituted or substituted by OR, and from C1-C6 alkyl, C1-C6 hydroxyalkyl, C1-C6 haloalkyl, C3-C6 cycloalkyl, halo, —OR, —(CH2)mOR, —NR2, —(CH2)mNR2, —NHR?, —SOmNR2, —SOmR, —SR, nitro, —CO2R, —CN, —CONR2, —NHCOR, —CH2NR10R11 and —NR10R11, in which each R is independently H or C1-C6 alkyl, R? is C3-C6 cycloalkyl and m is 1 or 2; R9 is selected from phenyl and 4- to 10-membered heteroaryl wherein phenyl and heteroaryl are unsubstituted or substituted by halo; R10 and R11 are each independently H or C1-C6 alkyl; or R10 and R11 form, together with the

Abstract: An implantable medical device for stimulating a human/animal heart having a stimulation unit which stimulates the His bundle and a detection unit which detects an electrical signal at the His bundle. The device performs: a) determining a first value of a parameter of a first measuring pulse measured between a first electrode pole and a housing; b) determining a second value of the same parameter of a second measuring pulse measured between the first electrode pole and a second electrode pole; c) comparing the first and second values; d) determining, based on the comparing step, whether the first or second measuring pulses enables a higher available level control range of the analog-to-digital converter; e) measuring an impedance in a unipolar manner between the first electrode pole and the housing or in a bipolar manner between the first electrode pole and the second electrode pole depending on the determining step.

Abstract: An antenna device, a transportation vehicle, and a textile article having an antenna device. The antenna device includes conductive filaments woven into a carrier fabric, wherein the conductive filaments form an antenna structure and are a contacting structure at a first end.

Abstract: An attenuation device for a CAN transceiver comprises two device output nodes configured to electrically couple the attenuation device via the device output nodes between two transceiver terminals of the CAN transceiver. The attenuation device is configured to change from a first device state to a second device state when a common mode voltage is applied to the device output nodes that is either greater than a first reference voltage or less than a second reference voltage that is less than the first reference voltage. The attenuation device causes a first electrical output resistance at each device output node during the first device state and causes a second electrical output resistance at each device output node during the second device state in which the second output resistance is less than the first output resistance.

Abstract: The present disclosure relates to a method for determining a conductivity value of a measurement medium using a conductivity sensor. The method includes providing a conductivity sensor with at least one transmitting unit, at least one receiving unit, and a control unit having a storage module, and transmitting a stimulation signal into the measurement medium at the transmitting unit by the control unit. The method also includes receiving a detection signal at the receiving unit, determining a signal quality indicator by the control unit based on the detection signal, and determining a conductivity signal corresponding to the detection signal. The method further includes storing the conductivity signal, determining a dynamic factor by the control unit based on the conductivity signal, filtering the conductivity signal using a filter function depending on the determined signal quality indicator and the dynamic factor, and outputting a filtered measured value of the filtered conductivity signal.

Abstract: A transmission device (2) for an electrically driveable vehicle (38), comprising a transmission element (9), a parking lock (12), by means of which the transmission element (9) can be blocked and which has a parking lock actuator (14), a transmission housing (7), which encloses the transmission element (9) and the parking lock (12), a connection apparatus (15) with a cable arrangement (16) extending in the transmission housing (7) and a plug connector by which a first end of the cable arrangement (16) can be contacted from the exterior of the transmission housing (7), wherein a second end of the cable arrangement (16) is electrically connected to the parking lock actuator (14), and a pressure equalization apparatus, which runs through the plug connector (17) of the connection apparatus (15) and forms a gas-permeable connection between the interior of the parking lock actuator (14) and the exterior of the transmission housing (7).

Abstract: A transmission device (1) for an electrically drivable vehicle (29), comprising a transmission element (2), a parking lock (6), by means of which the transmission element (2) can be blocked, a transmission housing (9), which encloses the transmission element (2) and the parking lock (6), a connection apparatus (10) with a cable arrangement (11) extending in the transmission housing (9) and to the first end of which a plug connector (12) is attached, the plug connector being arranged in a transmission housing opening (14) for contacting the cable arrangement (11) from the exterior of the transmission housing (9) and having contact elements (25) arranged in a plug connector housing (15), wherein a second end of the cable arrangement (11) is connected to the parking lock (6), wherein the plug connector (12) has at least one sealing means (18, 27) for preventing a lubricant from escaping through the transmission housing opening (14).

Abstract: An implantable medical device for stimulating a human or animal heart. In operation, the device performs the following steps: a) sensing an atrial electric signal a the first detection unit; b) sensing an electric signal at the His bundle with a second detection unit upon termination of a first time period starting upon sensing the atrial electric signal with the first detection unit and/or starting upon applying a stimulation pulse, wherein the first time period lies in a range of from 10 ms to 100 ms; c) classifying the electric signal sensed with the second detection unit as His bundle activity signal or as ventricular activity signal.

Abstract: A programming device for programming an implantable medical device for stimulating a human or animal heart, wherein the programming device carries out the steps: a) allowing to select one of at least two electrode lead configurations for stimulating a heart, wherein the at least two electrode lead configurations comprise: i) a first electrode lead in which an atrial electrode lead and a right ventricular electrode lead are connected to electrode lead ports, and ii) a second electrode lead in which an atrial electrode lead and a His bundle electrode lead are connected to electrode lead ports; b) allowing to select a first timing parameter value if the first electrode lead is selected and to select a second timing parameter value if the second electrode lead is selected, wherein the first timing parameter value is an atrioventricular interval and the second timing parameter value is an atrial-His interval.

Abstract: An implantable medical device for stimulating a human/animal heart having a stimulation unit which stimulates the His bundle and a detection unit which detects an electrical signal at the His bundle. The device performs: a) determining a first value of a parameter of a first measuring pulse measured between a first electrode pole and a housing; b) determining a second value of the same parameter of a second measuring pulse measured between the first electrode pole and a second electrode pole; c) comparing the first and second values; d) determining, based on the comparing step, whether the first or second measuring pulses enables a higher available level control range of the analog-to-digital converter; e) measuring an impedance in a unipolar manner between the first electrode pole and the housing or in a bipolar manner between the first electrode pole and the second electrode pole depending on the determining step.

Abstract: An implantable medical device for stimulating a human/animal heart, comprising a first electrode lead port for receiving an electrode lead. The first electrode lead port comprises a first marking element and a second marking element, wherein the first marking element indicates a first kind of electrode lead that can be received by the first electrode lead port and for an operation of which the first electrode lead port is designed to be configured, wherein the first kind of electrode lead is a His bundle electrode lead , wherein the second marking element indicates a second kind of electrode lead that can be received by the first electrode lead port and for an operation of which the first electrode lead port is designed to be configured. The second kind of electrode lead includes one of an atrial electrode lead, a right ventricular electrode lead, and a left ventricular electrode lead.

Abstract: A method for programming an implantable medical device for stimulating a human or animal heart with the help of a programming device. The method comprises the following steps: a) providing a first input parameter to the programming device, the first input parameter being indicative whether a first stimulation unit is to be used to stimulate the His bundle of a heart; b) if the first input parameter indicates that the first stimulation unit is to be used to stimulate the His bundle of the heart, supporting a user of the programming device to configure the implantable medical device for His bundle pacing by automatically proposing at least one stimulation parameter and an assigned stimulation parameter value specifically adapted for His bundle pacing; c) allowing programming of the implantable medical device by allowing setting the at least one stimulation parameter value.

Abstract: An implantable medical device for stimulating a human or animal heart, comprising a first processor, a first memory unit, a stimulation unit configured to stimulate a first cardiac region of a human or animal heart, and a detection unit configured to detect an electric signal at the first cardiac region of the same heart, wherein the detection unit comprises i) an electrode lead having an electrode pole and ii) a first channel for measuring electric signals provided by the electrode lead. A maximum sensitivity of the first channel of the detection unit is adjustable in dependence on a stimulation site of the electrode pole, wherein the maximum sensitivity of the first channel lies in a range of from 0.1 mV to 0.4 mV if the electrode pole is intended to detect electric signals at the His bundle of the heart.

Abstract: A programming device for programming an implantable medical device for stimulating a human or animal heart, wherein the following steps are performed: a) allowing to select one of at least two electrode lead configurations for stimulating a human or animal heart, wherein the at least two electrode lead configurations comprise a second electrode lead configuration in which at least one electrode lead is connected to an electrode lead port, the electrode lead port being configured to receive an electrode lead for stimulating a second cardiac region or detecting an electric signal at the second cardiac region, wherein the second cardiac region is a part of a ventricular conduction system of the heart, wherein the at least one electrode lead is intended to be implanted or is implanted in the second cardiac region; b) generating and releasing a notification signal if the second electrode lead configuration is selected.

Abstract: An implantable medical device for stimulating a human/animal heart, comprising a housing, a processor, a memory unit, a stimulation unit configured to stimulate the His bundle, and a detection unit configured to detect an electrical signal at the His bundle. The device performs: a) stimulating the His bundle with a stimulation pulse delivered by the stimulation unit; b) measuring an electric signal at the His bundle with the detection unit upon termination of a first period of time starting upon delivering of the stimulation pulse, wherein the first period of time is from 35 ms to 500 ms; c) measuring an impedance of the same heart with the detection unit upon termination of a second period of time starting upon delivering of the stimulation pulse, wherein the second period of time is equal to or longer than the first period of time and is from 50 ms to 500 ms.

Abstract: A method for measuring an electrical conductivity of a medium with a conductive conductivity sensor with four electrodes includes measuring a first impedance dependent on a first total impedance of the first voltage electrode and a medium layer adjacent to the first voltage electrode, measuring a second impedance dependent on a second total impedance of the second voltage electrode and a medium layer adjacent to the second voltage electrode, and making a conductivity measurement using an alternating electrical signal introduced into the medium via the first current electrode and measuring a potential difference between the first voltage electrode and the second voltage electrode. Based on the measured potential difference, the first impedance, and the second impedance a corrected potential difference is determined. Based on the corrected potential difference, a measured conductivity is determined.

Abstract: An electrochemical sensor comprising a probe immersible in a measured medium and having at least two electrodes of a first electrically conductive material and at least one probe body of a second, electrically non-conductive material. The electrodes are at least partially embedded in the probe body and insulated from one another by the probe body, wherein the at least two electrodes are embodied of at least one conductive material and the probe body of at least one electrically insulating ceramic, wherein the electrodes are embodied of thin, measuring active layers of a conductive material and sit in an end face of the probe body of a ceramic material, and wherein the electrodes are electrically contacted via connection elements extending through the probe body.

Abstract: An antenna device, a transportation vehicle, and a textile article having an antenna device. The antenna device includes conductive filaments woven into a carrier fabric, wherein the conductive filaments form an antenna structure and are a contacting structure at a first end.

Abstract: The present disclosure includes a method for correcting a primary measurement signal detected by an optical detector. The method includes: emitting a first light signal from a light source to an active sensor layer such that the active sensor layer is stimulated and emits a second light signal, which is detected by an optical detector; determining the primary measurement signal of a primary measurement parameter based on the second light signal and/or the first light signal; determining a secondary measurement signal of a secondary measurement parameter that is different from the primary measurement parameter based on the first light signal or the second light signal; comparing the determined secondary measurement signal with a first limit value; and correcting the primary measurement signal when the secondary measurement signal exceeds the first limit value, wherein correcting the primary measurement signal comprises smoothing the primary measurement signal by filtering.

Abstract: An assembly with a secondary coil arranged on a coil carrier for a field device is described, wherein the field device comprises an electronics and an inductive interface connected to the electronics, and wherein the assembly can be used in the field device such that the field device can be connected via its interface to an inductive interface of a superordinate unit such that the secondary coil of the assembly, with a primary coil of the inductive interface of the superordinate unit, form a transformer for transmitting data and/or energy, which makes it possible to reduce the dimensions of field devices equipped with it and also contributes to increased operational safety, in that an assembly circuit formed by the secondary coil and at least one electronic component connected to the secondary coil via lines connected to it and arranged on the coil carrier is arranged on the coil carrier.