Abstract: The present invention relates to processes for the preparation of sclareolide and related compounds by the biocatalytic cyclization of polyunsaturated carboxylic acid compounds, in particular of homofarnesylic acid and related compounds; and to a process for the preparation of ambroxide via the biocatalytic cyclization of homofarnesylic acid to sclareolide.

Abstract: The present invention relates to a method for the regioselective hydroformylation of polyunsaturated acyclic hydrocarbons, which are 1, 3 butadienes, which, in the 2 position, bear a saturated or monounsaturated or polyunsaturated acyclic hydrocarbon radical. The present invention also relates to the production of secondary products of these hydroformylation products, especially of ambrox.

Abstract: A process for preparing an arylpropene from a diarylpropane by gas phase thermolysis in the presence of solid porous catalyst comprising silica having large pore volume and low acidity.

Abstract: The present invention relates to a method for preparing compounds having a 16-oxabicyclo[10.3.1]pentadecene skeleton, specifically 14-methyl-16-oxabicyclo[10.3.1]pentadecenes, and conversion products thereof.

Abstract: The present invention relates to a method for preparing 2-substituted 4-hydroxy-4-methyltetrahydropyrans from starting materials comprising at least one 2-alkyl-4,4-dimethyl-1,3-dioxane.

Abstract: A process for preparing an arylpropene from a diarylpropane by gas phase thermolysis in the presence of boron containing zeolitic material comprising a membered ring (MR) pore system greater than 10 MR.

Abstract: The present invention relates to a process for preparing 3-methylcyclopentadecane-1,5-diol (I) by hydrogenolysis of 14-methyl-16,17,18-trioxatricyclo[10.3.2.1]octadecane (II). The invention further relates to a process for preparing 3-methylcyclopentadecane-1,5-diol is a macrocyclic diol that can serve as precursor for a macrocyclic odorant, such as muscone and muscenone.

Abstract: The present invention relates to the use of isomerically pure or highly isomerically enriched cis- or trans-(2-isobutyl-4-methyltetrahydropyran-4-yl) acetate for use as aroma chemicals. The invention further relates to a process for the preparation of isomerically pure or highly isomerically enriched cis- or trans-(2-isobutyl-4-methyltetrahydropyran-4-yl) acetate and the products obtainable by this process. The invention further relates to a fragrance or aroma substance composition which comprises isomerically pure or highly isomerically enriched cis- or trans-(2-isobutyl-4-methyltetra-hydropyran-4-yl) acetate, a method for imparting, and/or boosting an odor or taste of a product, and also perfumed or aromatized products which comprise isomerically pure or highly isomerically enriched cis- or trans-(2-isobutyl-4-methyltetrahydropyran-4-yl) acetate.

Abstract: The present invention relates to a process for preparing 1-(2,6,6-trimethylcyclohex-2-en-1-yl)but-2-en-1-one, which comprises a) providing 6,10-dimethylundeca-1,5,9-trien-4-ol, b) oxidizing 6,10-dimethylundeca-1,5,9-trien-4-ol provided in step a) with an oxidizing agent in the presence of at least one organic nitroxyl radical, at least one nitrate compound and an inorganic solid to yield 6,10-dimethylundeca-1,5,9-trien-4-one, c) reacting the 6,10-dimethylundeca-1,5,9-trien-4-one obtained in step b) with an acid to yield 1-(2,6,6-trimethylcyclohex-2-en-1-yl)but-2-en-1-one.

Abstract: The present invention relates to a method for preparing compounds having a 16-oxabicyclo[10.3.1]pentadecene skeleton, specifically 14-methyl-16-oxabicyclo[10.3.1]pentadecenes, and conversion products thereof.

Abstract: The present invention relates to a process for preparing 3-methylcyclopentadecane-1,5-diol (I) by hydrogenolysis of 14-methyl-16,17,18-trioxatricyclo[10.3.2.1]octadecane (II). The invention further relates to a process for preparing 3-methylcyclopentadecane-1,5-diol is a macrocyclic diol that can serve as precursor for a macrocyclic odorant, such as muscone and muscenone.

Abstract: The present invention relates to a method for preparing tetrahydropyranyl esters from the corresponding 4-hydroxytetrahydropyran compounds by reaction with a ketene compound.

Abstract: The present invention relates to a process for preparing, 4-bis(ethoxymethyl)cyclohexane, which comprises reacting 1,4-bis(hydroxymethyl)cyclohexane with ethyl chloride in the presence of an inorganic base, a solvent and a phase transfer catalyst to yield a reaction mixture containing 1,4-bis(ethoxymethyl)cyclohexane, where the inorganic base is selected from alkali metal hydroxides and earth alkaline metal hydroxides and where the solvent is selected from water or a mixture of water with at least one organic solvent.

Abstract: The present invention relates to a method for the regioselective hydroformylation of polyunsaturated acyclic hydrocarbons, which are 1, 3 butadienes, which, in the 2 position, bear a saturated or monounsaturated or polyunsaturated acyclic hydrocarbon radical. The present invention also relates to the production of secondary products of these hydroformylation products, especially of ambrox.

Abstract: The present invention relates to a process for preparing 1-(2,6,6-trimethylcyclohex-2-en-1-yl)but-2-en-1-one, which comprises a) providing 6,10-dimethylundeca-1,5,9-trien-4-ol, b) oxidizing 6,10-dimethylundeca-1,5,9-trien-4-ol provided in step a) with an oxidizing agent in the presence of at least one organic nitroxyl radical, at least one nitrate compound and an inorganic solid to yield 6,10-dimethylundeca-1,5,9-trien-4-one, c) reacting the 6,10-dimethylundeca-1,5,9-trien-4-one obtained in step b) with an acid to yield 1-(2,6,6-trimethylcyclohex-2-en-1-yl)but-2-en-1-one.

Abstract: The present invention relates to a process for preparing,4-bis(ethoxymethyl)cyclohexane, which comprises reacting1,4-bis(hydroxymethyl)cyclohexane with ethyl chloride in the presence of an inorganic base, a solvent and a phase transfer catalyst to yield a reaction mixture containing 1,4-bis(ethoxymethyl)cyclohexane, where the inorganic base is selected from alkali metal hydroxides and earth alkaline metal hydroxides and where the solvent is selected from water or a mixture of water with at least one organic solvent.

Abstract: The present invention relates to a process for preparing a macrocyclic diketone compound of the formula (I), which comprises the oxidation of a bicycloolefine compound of the formula (II) with an oxidizing agent, formulae (I) (II) where in formulae (I) and (II) A is (CH2)n with n being an integer from 2 to 12, where two hydrogen atoms may be replaced by C1-C4-alkyl, in particular methyl, or two hydrogen atoms, which are bound to adjacent carbon atoms may be replaced by a fused 5- or 6-membered saturated carbocycle; B is (CH2)m with m being 1 or 2, where 1 or 2 hydrogen atoms may be replaced by C1-C4-alkyl, in particular methyl.

Abstract: The present invention relates to a process for producing 3-methylcyclopentadecane-1,5-dione of formula (I), which comprises the oxidation of 14-methyl-bicyclo[10.3.0]pentadecen[1 (12)] of formula (II) with an oxidizing agent, where the oxidation is performed by using a mixture of formic acid with H2O2 as sole oxidizing agent in the presence of water and where the amount of H2O2 is at least 1.1 mol H2O2 per mol of the compound of formula (II).

Abstract: A process for preparing an arylpropene from a diarylpropane by gas phase thermolysis in the presence of solid porous catalyst comprising silica having large pore volume and low acidity.

Abstract: A process for preparing an arylpropene from a diarylpropane by gas phase thermolysis in the presence of boron containing zeolitic material comprising a membered ring (MR) pore system greater than 10 MR.