Patents by Inventor Stefan Roos

Stefan Roos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12295975
    Abstract: The invention relates to selection of bacterial strain for use in treating serotonin deficiency and/or a disease related to serotonin deficiency by culturing bacteria of a lactic acid producing bacterial strain, under aerobic conditions, in a culture medium comprising tryptophan. Any serotonin produced by the bacteria of the lactic acid producing bacterial strain in the culture medium is detected and the lactic acid producing bacterial strain is selected as effective in treating serotonin deficiency and/or a disease related to serotonin deficiency in a subject if serotonin is detected in the culture medium.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: May 13, 2025
    Assignee: BIOGAIA AB
    Inventors: Estelle Grasset, Muhammed Khan, Bo Möllstam, Stefan Roos
  • Patent number: 12171793
    Abstract: The present invention relates to methods of activating live lactic acid bacteria comprising exposing said bacteria to a preparation comprising citrate, wherein said bacteria have the ability to utilize citrate as an external electron acceptor. The present invention further relates to methods to enhance the activity of certain live bacteria in mammals. More specifically the invention relates to improve the wake-up of certain lactic acid bacteria from the freeze-dried state. The present invention also relates to preparations comprising said activated bacteria and therapeutic uses of said activated bacteria.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: December 24, 2024
    Assignee: INFANT BACTERIAL THERAPEUTICS AB
    Inventors: Staffan Stromberg, Eamonn Connolly, Stefan Roos
  • Publication number: 20240216447
    Abstract: The present invention relates to lactic acid bacterial strains which are capable of producing or inducing the production of melatonin, for use in the production of melatonin in a subject. Preferred strains for such uses are capable of producing or inducing the production of adenosine. Therapeutic uses of such strains include the treatment or prevention of diseases associated with melatonin deficiency, for example infantile colic. Novel strains are also provided.
    Type: Application
    Filed: January 18, 2024
    Publication date: July 4, 2024
    Applicant: BioGaia AB
    Inventors: Stefan Roos, Bo Möllstam
  • Publication number: 20240198244
    Abstract: An apparatus (1) serves for the amusement of persons. It has a fixed frame (2), on which a pivoting frame (3) is supported in an articulated manner about an approximately horizontal pivot axis (4). This pivoting frame (3) can be pivoted between an essentially vertical, closed position and a pivoted, exposed position. A net (5) or mesh is retained in the pivoting frame (3), and the person lies thereon in the exposed position. The pivoting frame (3) can be adjusted by means of at least one threaded spindle (8) with a self-locking thread pitch.
    Type: Application
    Filed: November 28, 2023
    Publication date: June 20, 2024
    Inventor: Stefan Roos
  • Publication number: 20240169668
    Abstract: A computer-implemented method is provided for creating a three-dimensional virtual model of an environment (2) of a motor vehicle (1). The method includes capturing images of the environment (2); determining a plurality of regions (3; 4; 5; 6; 7; 8; 9) in each of the images and calculating a region entropy for each of the regions (3; 4; 5; 6; 7; 8; 9). The method then proceeds by selecting at least one region (4; 9) that has a higher region entropy than other regions (3; 5; 6; 7; 8); and generating the three-dimensional virtual model by first ascertaining three-dimensional coordinates for the selected at least one region (4; 9) and only thereafter ascertaining three-dimensional coordinates for the unselected regions (3; 5; 6; 7; 8). The three-dimensional virtual model includes the three-dimensional coordinates of all regions (3; 4; 5; 6; 7; 8; 9).
    Type: Application
    Filed: November 17, 2023
    Publication date: May 23, 2024
    Inventors: Stefan Roos, Robin Schwager, Tim Bruehl, Lukas Ewecker
  • Publication number: 20240155058
    Abstract: A method for dynamically adjusting a volume level in an online meeting. The method includes step a. holding an online meeting in which participants can have a conversation with one another. In step b. using an AI algorithm, monitoring and recognizing content of a conversation of the participants in the online meeting and assigning content scores to the content, wherein each participant portion of the participants is assigned a recognized sub-content in the conversation based on the content scores. In step c. using the AI algorithm, recognizing a first intersection of content scores from a plurality of sub-contents, and recognizing a second or more intersections of content scores from other multiple sub-contents. In step d. adjusting volume levels of individual participants, by raising or lowering the volume level of a participant portion for such other participants having one or no intersection with the participant portion.
    Type: Application
    Filed: September 26, 2023
    Publication date: May 9, 2024
    Applicant: Dr. Ing. h.c. F. Porsche Aktiengesellschaft
    Inventors: Robin Schwager, Stefan Roos, Lukas Ewecker, Tim Brühl
  • Publication number: 20240082325
    Abstract: A method to provide therapeutic microvesicles from probiotic bacteria comprises exposing the bacteria to an inducing treatment during culturing to induce production of therapeutic microvesicles by the bacteria. The therapeutic microvesicles may be used in treatment of, for instance, colic, an infant or childhood gastrointestinal disorder or disease, a gastrointestinal pain disorder, a bone loss disease and/or a periodontal disease.
    Type: Application
    Filed: November 16, 2023
    Publication date: March 14, 2024
    Applicant: BioGaia AB
    Inventors: Stefan Roos, Wolfgang Kunze, John Bienenstock
  • Patent number: 11911424
    Abstract: The present invention relates to lactic acid bacterial strains which are capable of producing or inducing the production of melatonin, for use in the production of melatonin in a subject. Preferred strains for such uses are capable of producing or inducing the production of adenosine. Therapeutic uses of such strains include the treatment or prevention of diseases associated with melatonin deficiency, for example infantile colic. Novel strains are also provided.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: February 27, 2024
    Assignee: BioGaia AB
    Inventors: Stefan Roos, Bo Möllstam
  • Patent number: 11857582
    Abstract: A method to provide therapeutic microvesicles from probiotic bacteria comprises exposing the bacteria to an inducing treatment during culturing to induce production of therapeutic microvesicles by the bacteria. The therapeutic microvesicles may be used in treatment of, for instance, colic, an infant or childhood gastrointestinal disorder or disease, a gastrointestinal pain disorder, a bone loss disease and/or a periodontal disease.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: January 2, 2024
    Assignee: BioGaia AB
    Inventors: Stefan Roos, Wolfgang Kunze, John Bienenstock
  • Publication number: 20230362468
    Abstract: An optical sensor system (1) has plural optical lens systems (2a-2n), a single imaging optical sensor (3) and plural light guides (4a-4n) corresponding to the number of optical lens systems (2a-2n). The light guides (4a-4n) extend respectively between the lens systems (2a-2n) and the optical sensor (3). Each of the lens systems (2a-2n) is associated respectively with one of the light guides (4a-4n). A switching apparatus (5) selectively switches between the light guide means (4a-4n).
    Type: Application
    Filed: May 4, 2023
    Publication date: November 9, 2023
    Inventors: Simon Isele, Stefan Roos, Lukas Ewecker
  • Publication number: 20230338441
    Abstract: The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine. This characteristic makes it possible for the bacteria to compete for the same substrate as pathogenic ethanolamine-utilizing pathogens, thereby presenting an effective means to combat infections resulting from such pathogenic bacteria. There is also provided a method of selecting further ethanolamine-utilizing lactic acid bacteria, as well as other methods and uses involving said novel strains and other ethanolamine-utilizing lactic acid bacteria.
    Type: Application
    Filed: June 29, 2023
    Publication date: October 26, 2023
    Inventor: Stefan Roos
  • Patent number: 11730780
    Abstract: The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine. This characteristic makes it possible for the bacteria to compete for the same substrate as pathogenic ethanolamine-utilizing pathogens, thereby presenting an effective means to combat infections resulting from such pathogenic bacteria. There is also provided a method of selecting further ethanolamine-utilizing lactic acid bacteria, as well as other methods and uses involving said novel strains and other ethanolamine-utilizing lactic acid bacteria.
    Type: Grant
    Filed: February 14, 2022
    Date of Patent: August 22, 2023
    Assignee: BIOGAIA AB
    Inventor: Stefan Roos
  • Patent number: 11602551
    Abstract: The present invention provides the use of inosine in the treatment of a disease associated with Treg deficiency or Treg dysfunction, in particular immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX). In one embodiment of the invention, the inosine can be provided in the form of a bacterial strain that is capable of stimulating the production of inosine. Methods for stimulating the production of inosine in a subject using said strains are also provided, as are methods for the selection of a bacterial strain capable of stimulating inosine production in a subject.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: March 14, 2023
    Assignees: BioGaia AB, Board of Regents of the University of Texas System
    Inventors: Stefan Roos, Yuying Liu, Baokun He, Jon Marc Rhoads
  • Publication number: 20230057324
    Abstract: The present invention relates to lactic acid bacterial strains which are capable of producing or inducing the production of adenosine, for use in the production of adenosine in a subject. Therapeutic uses of such strains include the treatment or prevention of diseases associated with adenosine deficiency, for example wound healing. Novel strains are also provided.
    Type: Application
    Filed: July 24, 2019
    Publication date: February 23, 2023
    Applicant: BioGaia AB
    Inventor: Stefan Roos
  • Publication number: 20220354909
    Abstract: The invention relates to selection of bacterial strain for use in treating serotonin deficiency and/or a disease related to serotonin deficiency by culturing bacteria of a lactic acid producing bacterial strain, under aerobic conditions, in a culture medium comprising tryptophan. Any serotonin produced by the bacteria of the lactic acid producing bacterial strain in the culture medium is detected and the lactic acid producing bacterial strain is selected as effective in treating serotonin deficiency and/or a disease related to serotonin deficiency in a subject if serotonin is detected in the culture medium.
    Type: Application
    Filed: November 6, 2020
    Publication date: November 10, 2022
    Inventors: Estelle Grasset, Muhammed Khan, Bo Möllstam, Stefan Roos
  • Publication number: 20220347237
    Abstract: The present invention relates to lactic acid bacterial strains which are capable of producing or inducing the production of melatonin, for use in the production of melatonin in a subject. Preferred strains for such uses are capable of producing or inducing the production of adenosine. Therapeutic uses of such strains include the treatment or prevention of diseases associated with melatonin deficiency, for example infantile colic. Novel strains are also provided.
    Type: Application
    Filed: July 24, 2019
    Publication date: November 3, 2022
    Applicant: BioGaia AB
    Inventors: Stefan Roos, Bo Möllstam
  • Publication number: 20220168365
    Abstract: The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine. This characteristic makes it possible for the bacteria to compete for the same substrate as pathogenic ethanolamine-utilizing pathogens, thereby presenting an effective means to combat infections resulting from such pathogenic bacteria. There is also provided a method of selecting further ethanolamine-utilizing lactic acid bacteria, as well as other methods and uses involving said novel strains and other ethanolamine-utilizing lactic acid bacteria.
    Type: Application
    Filed: February 14, 2022
    Publication date: June 2, 2022
    Inventor: Stefan Roos
  • Patent number: 11285181
    Abstract: The present invention relates to novel strains of lactic acid bacteria, more specifically, novel strains of Lactobacillus reuteri, capable of utilizing ethanolamine. This characteristic makes it possible for the bacteria to compete for the same substrate as pathogenic ethanolamine-utilizing pathogens, thereby presenting an effective means to combat infections resulting from such pathogenic bacteria. There is also provided a method of selecting further ethanolamine-utilizing lactic acid bacteria, as well as other methods and uses involving said novel strains and other ethanolamine-utilizing lactic acid bacteria.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: March 29, 2022
    Assignee: Biogaia AB
    Inventor: Stefan Roos
  • Publication number: 20210154245
    Abstract: A method to provide therapeutic microvesicles from probiotic bacteria comprises exposing the bacteria to an inducing treatment during culturing to induce production of therapeutic microvesicles by the bacteria. The therapeutic microvesicles may be used in treatment of, for instance, colic, an infant or childhood gastrointestinal disorder or disease, a gastrointestinal pain disorder, a bone loss disease and/or a periodontal disease.
    Type: Application
    Filed: April 17, 2020
    Publication date: May 27, 2021
    Applicant: BioGaia AB
    Inventors: Stefan Roos, Wolfgang Kunze, John Bienenstock
  • Patent number: D1068106
    Type: Grant
    Filed: April 28, 2022
    Date of Patent: March 25, 2025
    Inventor: Stefan Roos