Patents by Inventor Stefan Sleijfer

Stefan Sleijfer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of cabazitaxel in the treatment of prostate cancer
    Patent number: 10555926
    Abstract: The present invention relates to cabazitaxel for use in a method for treating an AR-V7-positive patient suffering from prostate cancer comprising determining the AR-V7-status in said patient and administering cabazitaxel. The invention also relates to a method of identifying patients with prostate cancer, eligible for treatment with cabazitaxel comprising testing a biological sample from the patient for the presence of AR-V7 circulating tumor cells, wherein the patient is eligible for treatment with said cabazitaxel if circulating tumor cells in said sample test positive for AR-V7. The invention further relates to a kit of parts for determining the AR-V7-status in isolated tumor cells of a patient with prostate cancer.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: February 11, 2020
    Assignee: Erasmus University Medical Center Rotterdam
    Inventors: Stefan Sleijfer, Wendy Onstenk, Anita Maria Sieuwerts
  • USE OF CABAZITAXEL IN THE TREATMENT OF PROSTATE CANCER
    Publication number: 20180064678
    Abstract: The present invention relates to cabazitaxel for use in a method for treating an AR-V7-positive patient suffering from prostate cancer comprising determining the AR-V7-status in said patient and administering cabazitaxel. The invention also relates to a method of identifying patients with prostate cancer, eligible for treatment with cabazitaxel comprising testing a biological sample from the patient for the presence of AR-V7 circulating tumor cells, wherein the patient is eligible for treatment with said cabazitaxel if circulating tumor cells in said sample test positive for AR-V7. The invention further relates to a kit of parts for determining the AR-V7-status in isolated tumor cells of a patient with prostate cancer.
    Type: Application
    Filed: February 17, 2016
    Publication date: March 8, 2018
    Inventors: Stefan Sleijfer, Wendy Onstenk, Anita Maria Sieuwerts
  • IDENTIFYING CIRCULATING TUMOR CELLS (CTCS) USING CD146 IN BREAST CANCER PATIENTS
    Publication number: 20120178645
    Abstract: The present invention relates to a method for diagnosing cancer in a subject said method comprising the steps of providing a biological sample from a subject, and determining the expression of the MCAM gene in a circulating tumor cell (CTC) in said biological sample.
    Type: Application
    Filed: June 26, 2009
    Publication date: July 12, 2012
    Inventors: Johannes Albert Foekens, Johannes Wihelmus Maria Martens, Jaco Kraan, Stefan Sleijfer, Bianca Mostert, Anita Maria Sieuwerts