Patents by Inventor Stefan Stevanovic

Stefan Stevanovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150320848
    Abstract: The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to several novel peptide sequences and their variants derived from HLA class I and HLA class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
    Type: Application
    Filed: May 8, 2015
    Publication date: November 12, 2015
    Inventors: Hans-Georg RAMMENSEE, Stefan STEVANOVIC, Juliane STICKEL, Daniel KOWALEWSKI, Claudia BERLIN
  • Patent number: 9023804
    Abstract: Methods and compositions for immunotherapeutic treatment of prostate cancer are disclosed. More specifically methods of treating patients with prostate cancer comprising administering compositions comprising HLA-binding peptides derived from prostate-associated antigenic molecules, either with or without immunological adjuvants, are disclosed.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: May 5, 2015
    Assignee: Immatics Biotechnologies GmbH
    Inventors: Toni Weinschenk, Peter Lewandrowski, Hans Georg Rammensee, Stefan Stevanovic, Cecile Gouttefangeas
  • Patent number: 9023802
    Abstract: Methods and compositions for immunotherapeutic treatment of prostate cancer are disclosed. Patients are treated with compositions comprising HLA-binding peptides derived from prostate-associated antigenic molecules, either with or without immunological adjuvants.
    Type: Grant
    Filed: December 14, 2010
    Date of Patent: May 5, 2015
    Assignee: Immatics Biotechnologies GmbH
    Inventors: Hans Georg Rammensee, Stefan Stevanovic, Cecile Gouttefangeas, Toni Weinschenk, Peter Lewandrowski
  • Publication number: 20140127242
    Abstract: The present invention relates to peptides, nucleic acids, and cells for use in the immunotherapy of cancer. The present invention furthermore relates to survivin-derived tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention specifically relates to three novel peptide sequences and variants thereof derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
    Type: Application
    Filed: June 19, 2012
    Publication date: May 8, 2014
    Applicant: IMMATICS BIOTECHNOLOGIES GMBH
    Inventors: Hans-Georg RAMMENSEE, Stefan STEVANOVIC, Cécile GOUTTEFANGES, Toni WEINSCHENK, Peter LEWANDROWSKI
  • Patent number: 8647629
    Abstract: The present invention relates to peptides, nucleic acids, and cells for use in the immunotherapy of cancer. The present invention furthermore relates to survivin-derived tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention specifically relates to three novel peptide sequences and variants thereof derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: February 11, 2014
    Assignee: Immatics Biotechnologies GmbH
    Inventors: Hans-Georg Rammensee, Stefan Stevanovic, Cécile Gouttefanges, Toni Weinschenk, Peter Lewandrowski
  • Publication number: 20130336922
    Abstract: Methods and compositions for immunotherapeutic treatment of prostate cancer are disclosed. More specifically methods of treating patients with prostate cancer comprising administering compositions comprising HLA-binding peptides derived from prostate-associated antigenic molecules, either with or without immunological adjuvants, are disclosed.
    Type: Application
    Filed: November 14, 2011
    Publication date: December 19, 2013
    Applicant: IMMATICS BIOTECHNOLOGIES GMBH
    Inventors: Toni Weinschenk, Peter Lewandrowski, Hans Georg Rammensee, Stefan Stevanovic, Cecile Gouttefangeas
  • Publication number: 20130323272
    Abstract: The present invention relates to peptides, nucleic acids, and cells for use in the immunotherapy of cancer. The present invention furthermore relates to survivin-derived tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention specifically relates to three novel peptide sequences and variants thereof derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
    Type: Application
    Filed: June 28, 2013
    Publication date: December 5, 2013
    Applicant: IMMATICS BIOTECHNOLOGIES GMBH
    Inventors: Hans Georg Rammensee, Stefan Stevanovic, Cecile Gouttefanges, Toni Weinschenk, Peter Lewandrowski
  • Patent number: 8536304
    Abstract: The invention relates to a tumor-associated peptide containing an amino sequence, which is selected from the group consisting of SEQ ID NO:1 to SEQ ID NO:79 of the enclosed listing. The peptide has the ability to bind to a molecule of the human major histocompatibility complex (MHC) class-I. The invention also relates to the use of the peptides for manufacture of a medicament and for treating tumorous diseases. The invention further relates to a pharmaceutical composition, which comprises at least one of the peptides.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: September 17, 2013
    Assignee: Immatics Biotechnologies GmbH
    Inventors: Toni Weinschenk, Hans Georg Rammensee, Stefan Stevanovic
  • Patent number: 8399613
    Abstract: The invention relates to a tumor-associated peptide containing an amino sequence, which is selected from the group consisting of SEQ ID NO:1 to SEQ ID NO:79 of the enclosed listing. The peptide has the ability to bind to a molecule of the human major histocompatibility complex (MHC) class-I. The invention also relates to the use of the peptides for manufacture of a medicament and for treating tumorous diseases. The invention further relates to a pharmaceutical composition, which comprises at least one of the peptides.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: March 19, 2013
    Assignee: Immatics Biotechnologies GmbH
    Inventors: Toni Weinschenk, Hans Georg Rammensee, Stefan Stevanovic
  • Patent number: 8242239
    Abstract: The invention relates to a tumor-associated peptide with an amino acid sequence selected from the group consisting of SEQ ID NO. 1 to SEQ ID NO. 577 from the attached sequence protocol, the peptide being capable of binding to a molecule of the human major histocompatibility complex (MHC) class I. The invention further relates to the use of the peptides for preparation of a drug and for the treatment of tumor diseases and/or adenomatous diseases. Furthermore, a pharmaceutical composition is described comprising at least one of the peptides.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: August 14, 2012
    Assignee: Immatics Biotechnologies GmbH
    Inventors: Toni Weinschenk, Claudia Lemmel, Hans-Georg Rammensee, Stefan Stevanovic
  • Publication number: 20120082691
    Abstract: Methods and compositions for immunotherapeutic treatment of prostate cancer are disclosed. Patients are treated with compositions comprising HLA-binding peptides derived from prostate-associated antigenic molecules, either with or without immunological adjuvants.
    Type: Application
    Filed: December 14, 2010
    Publication date: April 5, 2012
    Applicant: IMMATICS BIOTECHNOLOGIES GMBH
    Inventors: Hans Georg Rammensee, Stefan Stevanovic, Cecile Gouttefangeas, Toni Weinschenk, Peter Lewandrowski
  • Patent number: 8008431
    Abstract: The invention relates to a tumor-associated peptide with an amino acid sequence selected from the group consisting of SEQ ID NO. 1 to SEQ ID NO. 577 from the attached sequence protocol, the peptide being capable of binding to a molecule of the human major histocompatibilityg complex (MHC) class I. The invention further relates to the use of the peptides for preparation of a drug and for the treatment of tumor diseases and/or adenomatous diseases. Furthermore, a pharmaceutical composition is described comprising at least one of the peptides.
    Type: Grant
    Filed: May 24, 2005
    Date of Patent: August 30, 2011
    Assignee: Immatics Biotechnologies GmbH
    Inventors: Toni Weinschenk, Claudia Lemmel, Hans-Georg Rammensee, Stefan Stevanovic
  • Publication number: 20110070253
    Abstract: The invention relates to a tumour-associated peptide with an amino acid sequence that is selected from the group consisting of SEQ ID NO: 1 to SEQ ID NO: 101 of the attached sequence protocol, wherein the peptide has the ability to bind to a molecule of the human major-histocompatibility-complex (MHC) class-I. In addition, the invention relates to the use of the peptides and the nucleic acids encoding for the peptides for the production of a medicament, and for the treatment of tumorous diseases and/or adenomatous diseases. Furthermore, a pharmaceutical composition is described that has at least one of the peptides.
    Type: Application
    Filed: October 29, 2010
    Publication date: March 24, 2011
    Applicant: IMMATICS BIOTECHNOLOGIES GMBH
    Inventors: Hans Georg RAMMENSEE, Stefan Stevanovic, Toni Weinschenk, Claudia Trautwein, Jörn Dengjel, Oliver Schoor
  • Patent number: 7763711
    Abstract: The invention relates to a tumor-associated peptide containing an amino sequence, which is selected from the group consisting of SEQ ID NO:1 to SEQ ID NO:79 of the enclosed listing. The peptide has the ability to bind to a molecule of the human major histocompatibility complex (MHC) class-I. The invention also relates to the use of the peptides for manufacture of a medicament and for treating tumorous diseases. The invention further relates to a pharmaceutical composition, which comprises at least one of the peptides.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: July 27, 2010
    Assignee: Immatics Biotechnologies GmbH
    Inventors: Toni Weinschenk, Hans Georg Rammensee, Stefan Stevanovic
  • Publication number: 20100183644
    Abstract: The invention relates to a tumor-associated peptide containing an amino sequence, which is selected from the group consisting of SEQ ID NO:1 to SEQ ID NO:79 of the enclosed listing. The peptide has the ability to bind to a molecule of the human major histocompatibility complex (MHC) class-I. The invention also relates to the use of the peptides for manufacture of a medicament and for treating tumorous diseases. The invention further relates to a pharmaceutical composition, which comprises at least one of the peptides.
    Type: Application
    Filed: January 22, 2010
    Publication date: July 22, 2010
    Applicant: IMMATICS BIOTECHNOLOGIES GMBH
    Inventors: Toni Weinschenk, Hans Georg Rammensee, Stefan Stevanovic
  • Publication number: 20100184211
    Abstract: The invention relates to a tumor-associated peptide containing an amino sequence, which is selected from the group consisting of SEQ ID NO:1 to SEQ ID NO:79 of the enclosed listing. The peptide has the ability to bind to a molecule of the human major histocompatibility complex (MHC) class-I. The invention also relates to the use of the peptides for manufacture of a medicament and for treating tumorous diseases. The invention further relates to a pharmaceutical composition, which comprises at least one of the peptides.
    Type: Application
    Filed: January 22, 2010
    Publication date: July 22, 2010
    Applicant: IMMATICS BIOTECHNOLOGIES GMBH
    Inventors: TONI WEINSCHENK, HANS GEORG RAMMENSEE, STEFAN STEVANOVIC
  • Patent number: 7666984
    Abstract: The invention relates to a tumor-associated peptide containing an amino sequence, which is selected from the group consisting of SEQ ID NO:1 to SEQ ID NO:79 of the enclosed listing. The peptide has the ability to bind to a molecule of the human major histocompatibility complex (MHC) class-I. The invention also relates to the use of the peptides for manufacture of a medicament and for treating tumorous diseases. The invention further relates to a pharmaceutical composition, which comprises at least one of the peptides.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: February 23, 2010
    Assignee: Immatics Biotechnologies, GmbH
    Inventors: Toni Weinschenk, Hans Georg Rammensee, Stefan Stevanovic
  • Publication number: 20100029571
    Abstract: The present invention relates to peptides, nucleic acids, and cells for use in the immunotherapy of cancer. The present invention furthermore relates to survivin-derived tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention specifically relates to three novel peptide sequences and variants thereof derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
    Type: Application
    Filed: May 14, 2009
    Publication date: February 4, 2010
    Applicant: IMMATICS BIOTECHNOLOGIES GMBH
    Inventors: Hans-Georg RAMMENSEE, Stefan STEVANOVIC, Cecile GOUTTEFANGES, Toni WEINSCHENK, Peter LEWANDROWSKI
  • Publication number: 20100029573
    Abstract: The invention relates to a tumor-associated peptide with an amino acid sequence selected from the group consisting of SEQ ID NO. 1 to SEQ ID NO. 577 from the attached sequence protocol, the peptide being capable of binding to a molecule of the human major histocompatibility complex (MHC) class I. The invention further relates to the use of the peptides for preparation of a drug and for the treatment of tumor diseases and/or adenomatous diseases. Furthermore, a pharmaceutical composition is described comprising at least one of the peptides.
    Type: Application
    Filed: May 24, 2005
    Publication date: February 4, 2010
    Applicant: Immatics Biotechnologies GmbH
    Inventors: Toni Weinschenk, Claudia Lemmel, Hans-Georg Rammensee, Stefan Stevanovic
  • Publication number: 20100021441
    Abstract: The invention relates to a tumor-associated peptide with an amino acid sequence selected from the group consisting of SEQ ID NO. 1 to SEQ ID NO. 577 from the attached sequence protocol, the peptide being capable of binding to a molecule of the human major histocompatibility complex (MHC) class I. The invention further relates to the use of the peptides for preparation of a drug and for the treatment of tumor diseases and/or adenomatous diseases.
    Type: Application
    Filed: August 19, 2009
    Publication date: January 28, 2010
    Applicant: IMMATICS BIOTECHNOLOGIES GMBH
    Inventors: Toni WEINSCHENK, Claudia Lemmel, Hans-Georg Rammensee, Stefan Stevanovic