Abstract: A method for a cloud-based feedback-driven image training and recognition includes receiving a set of expert annotations of a plurality of training images of a predetermined subject matter, wherein the expert annotations include a clinical diagnosis for each image or region of interest in an image, training one or more classification models from the set of expert annotations, testing the one or more classification models on a plurality of test images that are different from the training images, wherein each classification model yields a clinical diagnosis for each image and a confidence score for that diagnosis, and receiving expert classification result feedback regarding the clinical diagnosis for each image and a confidence score yielded by each classification model.