Patents by Inventor Stefan Walter Hell

Stefan Walter Hell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and system for imaging a molecular strand
    Patent number: 9766180
    Abstract: The present disclosure concerns a method and system for imaging a molecular strand (MS). The method comprises providing a sample volume (SV) comprising the strand (MS); providing an excitation beam (EB) having an excitation focus (EF) in the sample volume (SV); scanning the excitation focus (EF) in the sample volume (SV) along a one dimensional scanning line (SL); trapping an end of the strand (MS) in the sample volume (SV) and extending the strand (MS) along a one-dimensional trapping line (LL) parallel to the scanning line (SL); aligning the trapping line (LL) to coincide with the scanning line (SL) to have the scanning excitation focus (EF) coincide with the strand (MS); and recording the fluorescence response (FR) as a function of a plurality of distinct scanning positions (X0) of the excitation focus (EF) along the scanning line (SL).
    Type: Grant
    Filed: June 2, 2014
    Date of Patent: September 19, 2017
    Assignee: Stichting VU-VUmc
    Inventors: Gijs Jan Lodewijk Wuite, Erwin Johannes Gerard Peterman, Iddo Heller, Gerrit Sitters, Andrea Candelli, Stefan Walter Hell
  • METHOD AND SYSTEM FOR IMAGING A MOLECULAR STRAND
    Publication number: 20160139050
    Abstract: The present disclosure concerns a method and system for imaging a molecular strand (MS). The method comprises providing a sample volume (SV) comprising the strand (MS); providing an excitation beam (EB) having an excitation focus (EF) in the sample volume (SV); scanning the excitation focus (EF) in the sample volume (SV) along a one dimensional scanning line (SL); trapping an end of the strand (MS) in the sample volume (SV) and extending the strand (MS) along a one-dimensional trapping line (LL) parallel to the scanning line (SL); aligning the trapping line (LL) to coincide with the scanning line (SL) to have the scanning excitation focus (EF) coincide with the strand (MS); and recording the fluorescence response (FR) as a function of a plurality of distinct scanning positions (X0) of the excitation focus (EF) along the scanning line (SL).
    Type: Application
    Filed: June 2, 2014
    Publication date: May 19, 2016
    Inventors: Gijs Jan Lodewijk Wuite, Erwin Johannes Gerard Peterman, Iddo Heller, Gerrit Sitters, Andrea Candelli, Stefan Walter Hell