Patents by Inventor Stefan Weisshaar
Stefan Weisshaar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11794154Abstract: A mixing apparatus (1) for mixing a fluid and/or solid. The mixing apparatus includes a mixing container (100) having an interior in which the fluid and/or solid can be arranged. A feed-through passage (10) extends through a container wall (101) of the mixing container. A drive shaft (50) is fed through the feed-through passage, to drive a stirring element (30) arranged at least partly in the interior of the mixing container. The stirring element is used to mix the fluid and/or solid arranged in the mixing container. A drive-side shaft end (51) of the drive shaft couples the drive shaft to a drive (120) arranged outside of the mixing container. An adjustable seal (70) seals off the feed-through passage. A setting apparatus (80) is provided to switch the adjustable seal into at least two sealing operation states having different sealing effects.Type: GrantFiled: February 10, 2020Date of Patent: October 24, 2023Assignee: SARTORIUS STEDIM BIOTECH GMBHInventors: Stefan Zeuch, Markus Haeusser, Stefan Weisshaar, Jens Ludwig
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Publication number: 20210252517Abstract: A configurable device arrangement for performing at least one unit operation in a biopharmaceutical process includes a base rack and a plurality of holders for releasable direct or indirect attachment of process components, in particular single-use process components, for the unit operation. The holders are in turn adapted to be releasably attached directly or indirectly to the base rack. The device arrangement further includes a positioning system which defines specific positions for the holders relative to the base rack.Type: ApplicationFiled: November 12, 2019Publication date: August 19, 2021Inventors: Stefan WEISSHAAR, Mario DEUSE, Martin LEUTHOLD, Thomas KRUMBEIN
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Publication number: 20210102155Abstract: A modular processing system (100) for biopharmaceutical processes includes (i) at least one first and at least one second processing unit (30, 32), which can be fluidically connected to each other; and (ii) at least one adapter plate (200), through which at least one fluid flow (14), flowing from the first processing unit (30) to the second processing unit (32), can flow. The adapter plate deflects the fluid flow between the first processing unit and the second processing unit at least partially; and/or controls the fluid flow, preferably, the pressure thereof, in an open loop or closed loop manner. A method for the modular construction of a processing system (100) for biopharmaceutical processes is also disclosed.Type: ApplicationFiled: December 18, 2020Publication date: April 8, 2021Inventors: Martin LEUTHOLD, Stefan WEISSHAAR
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Publication number: 20200276539Abstract: A filter device (10), in particular for a tangential flow filtration device, has at least one fluid inlet (22), at least one retentate outlet (24) and at least one permeate outlet (26). The filter device (10) further has at least one membrane (16) which separates a retentate section (18) from a permeate section (20) in the filter device (10). Arranged in the retentate section (18) and/or in the permeate section (20) is at least one flow fitting (28) which is not formed from a woven or non-woven fabric, but from a structured plastic part, silicone part, metal part or ceramic part.Type: ApplicationFiled: September 17, 2018Publication date: September 3, 2020Inventors: Stefan WEISSHAAR, Martin LEUTHOLD, Ulrich GRUMMERT, Matthias WESSLING, Kristina BAITALOW, Jonas LOELSBERG
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Publication number: 20200171450Abstract: A mixing apparatus (1) for mixing a fluid and/or solid. The mixing apparatus includes a mixing container (100), in the interior of which the fluid and/or solid can be arranged, and a feed-through (10) through a container wall (101) of the mixing container (100). A drive shaft (50), fed through the feed-through (10), is used to drive a stirring element (30), which is arranged at least partly in the interior of the mixing container (100), in order to mix the fluid and/or solid, arranged in the mixing container (100). A drive-side shaft end (51) of the drive shaft (50) is used to couple a drive (120), arranged outside of the mixing container (100), to the drive shaft (50). An adjustable seal (70) seals off the feed-through (10), wherein the adjustable seal (70) can be put into at least two sealing operation states having different sealing effects.Type: ApplicationFiled: February 10, 2020Publication date: June 4, 2020Inventors: Stefan ZEUCH, Markus HAEUSSER, Stefan WEISSHAAR, Jens LUDWIG
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Patent number: 10525413Abstract: A connecting system (1) has at least one connector (2) for a filter cassette (4) that can be inserted into a filter holder and has filter layers (5) between two end plates (6), and seals (7) between the filter layers (5) and/or between the end plates (6) and an adjacent filter layer (5). The connector has tensioning parts that engage in one another in a longitudinally displaceable manner and that can be fixed to the end plates (6) via their ends facing away from one another. The connector exerts a pretensioning force onto the end plates (6) when it is deflected to its maximum extent. The pretensioning force pulls the end plates (6) towards the filter layers (5), and when a contact-pressure force superimposed on the pretensioning force is applied to the end plates (6), the tensioning parts can be pushed towards one another correspondingly with the end plates (6).Type: GrantFiled: October 30, 2014Date of Patent: January 7, 2020Assignee: Sartorius Stedim Biotech GmbHInventors: Thomas Krumbein, Stefan Weisshaar, Michael Bates
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Patent number: 10427112Abstract: Aeration device for bioreactors with an aeration element with gas outlet openings arranged in a housing, the aeration element taking the form of a microsparger, the gas outlet openings of which are in each case spaced apart from one another and have a size of between 100 ?m and 200 ?m. At least one second aeration element with gas outlet openings of a second size is preferably provided, the aeration elements being formed by a common housing with separate aeration channels.Type: GrantFiled: August 6, 2011Date of Patent: October 1, 2019Assignee: SARTORIUS STEDIM BIOTECH GMBHInventor: Stefan Weisshaar
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Patent number: 9669333Abstract: One aspect of the invention relates to a filter module comprising: —a filter element having at least one filter medium which separates a filtrate side and a retentate side of the filter element from one another, and having a filter medium holder to which the filter medium is attached and which has at least one holder intake channel and at least one holder discharge channel, —a first filter cartridge part having at least one first cartridge intake channel and at least one first cartridge discharge channel, —a second filter cartridge channel having at least one second cartridge intake channel and at least one second cartridge discharge channel, wherein the filter medium holder is arranged in an arrangement position between the first filter cartridge part and the second filter cartridge part in a fluid-tight manner, wherein the at least one holder intake channel has a fluid connection with the at least one first cartridge intake channel and the at least one second cartridge intake channel, in order to form a modType: GrantFiled: February 8, 2013Date of Patent: June 6, 2017Assignee: Sartorius Stedim Biotech GmbHInventors: Martin Leuthold, Stefan Weisshaar, Christoph Schich, Thomas Krumbein
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Patent number: 9636644Abstract: Aeration device for bioreactors with a first aeration element with gas outlet openings of a first size and with at least one second aeration element with gas outlet openings of a second size, the aeration elements being formed by a common housing with separate aeration channels.Type: GrantFiled: October 28, 2010Date of Patent: May 2, 2017Assignee: SARTORIUS STEDIM BIOTECH GMBHInventors: Guenter Pradel, Stefan Weisshaar, Gerhard Greller, Ute Husemann
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Publication number: 20160288054Abstract: A connecting system (1) has at least one connector (2) for a filter cassette (4) that can be inserted into a filter holder and has filter layers (5) between two end plates (6), and seals (7) between the filter layers (5) and/or between the end plates (6) and an adjacent filter layer (5). The connector has tensioning parts that engage in one another in a longitudinally displaceable manner and that can be fixed to the end plates (6) via their ends facing away from one another. The connector exerts a pretensioning force onto the end plates (6) when it is deflected to its maximum extent. The pretensioning force pulls the end plates (6) towards the filter layers (5), and when a contact-pressure force superimposed on the pretensioning force is applied to the end plates (6), the tensioning parts can be pushed towards one another correspondingly with the end plates (6).Type: ApplicationFiled: October 30, 2014Publication date: October 6, 2016Inventors: Thomas Krumbein, Stefan Weisshaar, Michael Bates
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Patent number: 9228784Abstract: The invention relates to a plate heat exchanger comprising a plurality of plates having flow channels, wherein a first plate has a front side having at least one flow channel for a first fluid and a second plate has a front side having at least one flow channel for a second fluid, and wherein the plates have through openings via which the flow channels for the same fluid are respectively connected to one another, wherein a front plate, which is placed in front of the front side of the first plate, has ports for the first fluid and for the second fluid, wherein an end plate forms the end of the aligned plates, wherein the plates and ports are formed from plastic, and wherein the plates are bonded or welded tightly together.Type: GrantFiled: June 10, 2010Date of Patent: January 5, 2016Assignee: Sartorius Stedim Biotech GmbHInventors: Oscar-Werner Reif, Juergen van den Boogaard, Stefan Weisshaar
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Publication number: 20150001147Abstract: One aspect of the invention relates to a filter module comprising: —a filter element having at least one filter medium which separates a filtrate side and a retentate side of the filter element from one another, and having a filter medium holder to which the filter medium is attached and which has at least one holder intake channel and at least one holder discharge channel, —a first filter cartridge part having at least one first cartridge intake channel and at least one first cartridge discharge channel, —a second filter cartridge channel having at least one second cartridge intake channel and at least one second cartridge discharge channel, wherein the filter medium holder is arranged in an arrangement position between the first filter cartridge part and the second filter cartridge part in a fluid-tight manner, wherein the at least one holder intake channel has a fluid connection with the at least one first cartridge intake channel and the at least one second cartridge intake channel, in order to form a modType: ApplicationFiled: February 8, 2013Publication date: January 1, 2015Inventors: Martin Leuthold, Stefan Weisshaar, Christoph Schich, Thomas Krumbein
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Patent number: 8859949Abstract: A sensor device has an optical sensor (1), a container (2) and a compartmentalizer (3) that temporarily divides the container into a main space (4) and an adjacent space (5), in which the optical sensor (1) is located. The gas volume in the direct vicinity of the optical sensor (1) is reduced, as are also, consequently, the reactive products generated by radiation sterilization. The adjacent space (5) can be united with the main space (4) after the sterilization as a result of the temporary compartmentalization. The optical sensor is suitable for implementation in containers and laboratory products, such as, for example, disposable bioreactors, that are sterilized by gamma radiation.Type: GrantFiled: May 22, 2010Date of Patent: October 14, 2014Assignee: Sartorius Stedim Biotech GmbHInventors: Reinhard Baumfalk, Stefan Weisshaar, Gerhard Greller, Daniel Riechers, Julia Lueders, Peter Polossek
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Patent number: 8809765Abstract: A sensor protector is intended to reduce the sensitivity of the optical sensor (4) to radiation products which, for example, are formed during sterilization with gamma radiation and to ensure simple and cost-effective manufacture. The sensor protector includes an upper part (1), a lower part (3) and an optical sensor (4). The optical sensor (4) situated on the lower part is positionable in an offset manner with respect to an opening (2) situated in the upper part and movable by means of displacement toward the opening (2) of the upper part (1). The sensor protector is suitable for use in containers and laboratory products that are sterilized by gamma radiation, for example disposable bioreactors.Type: GrantFiled: November 12, 2010Date of Patent: August 19, 2014Assignee: Sartorius Stedim Biotech GmbHInventors: Stefan Weisshaar, Michael Bates, Christian Pradel, Volker Limpert
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Publication number: 20130175716Abstract: Aeration device for bioreactors with an aeration element with gas outlet openings arranged in a housing, the aeration element taking the form of a microsparger, the gas outlet openings of which are in each case spaced apart from one another and have a size of between 100 ?m and 200 ?m. At least one second aeration element with gas outlet openings of a second size is preferably provided, the aeration elements being formed by a common housing with separate aeration channels.Type: ApplicationFiled: August 6, 2011Publication date: July 11, 2013Applicant: SARTORIUS STEDIM BIOTECH GMBHInventor: Stefan Weisshaar
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Publication number: 20120313267Abstract: Aeration device for bioreactors with a first aeration element with gas outlet openings of a first size and with at least one second aeration element with gas outlet openings of a second size, the aeration elements being formed by a common housing with separate aeration channels.Type: ApplicationFiled: October 28, 2010Publication date: December 13, 2012Applicant: SARTORIUS STEDIM BIOTECH GMBHInventors: Guenter Pradel, Stefan Weisshaar, Gerhard Greller, Ute Husemann
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Publication number: 20120267518Abstract: A sensor protector is intended to reduce the sensitivity of the optical sensor (4) to radiation products which, for example, are formed during sterilization with gamma radiation and to ensure simple and cost-effective manufacture. The sensor protector includes an upper part (1), a lower part (3) and an optical sensor (4). The optical sensor (4) situated on the lower part is positionable in an offset manner with respect to an opening (2) situated in the upper part and movable by means of displacement toward the opening (2) of the upper part (1). The sensor protector is suitable for use in containers and laboratory products that are sterilized by gamma radiation, for example disposable bioreactors.Type: ApplicationFiled: November 12, 2010Publication date: October 25, 2012Applicant: Sartorius Stedim Biotech GmbHInventors: Stefan Weisshaar, Michael Bates, Christian Pradel, Volker Limpert
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Patent number: D740391Type: GrantFiled: August 12, 2014Date of Patent: October 6, 2015Assignee: Sartorius Stedim Biotech GmbHInventors: Alexander Mueller, Dirk Lamprecht, Thomas Krumbein, Stefan Weisshaar, Michael Bates
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Patent number: D741983Type: GrantFiled: August 12, 2014Date of Patent: October 27, 2015Assignee: Sartorius Stedim Biotech GmbHInventors: Alexander Mueller, Dirk Lamprecht, Thomas Krumbein, Stefan Weisshaar, Michael Bates
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Patent number: D895059Type: GrantFiled: March 26, 2018Date of Patent: September 1, 2020Assignee: SARTORIUS STEDIM BIOTECH GMBHInventors: Thomas Krumbein, Stefan Weisshaar, Michael Bates