Patents by Inventor Stefan Zahn

Stefan Zahn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210238300
    Abstract: The present invention concerns human antibodies recognising the human C5a receptor. By binding to C5aR the antibodies inhibit C5a signalling, whereby the pro-inflammatory signal is inhibited. Based on the role of C5a and its receptor in stimulation of inflammation the invention further relates to therapeutic use of said human anti-C5aR antibodies and in particular in relation to treatment of immunological disorders.
    Type: Application
    Filed: December 18, 2020
    Publication date: August 5, 2021
    Inventors: Kristian Kjaergaard, Soeren Lund, Stefan Zahn, Louise H. Zeuthen, Anker J. Hansen
  • Patent number: 10882916
    Abstract: The present invention concerns human antibodies recognising the human C5a receptor. By binding to C5aR the antibodies inhibit C5a signalling, whereby the pro-inflammatory signal is inhibited. Based on the role of C5a and its receptor in stimulation of inflammation the invention further relates to therapeutic use of said human anti-C5aR antibodies and in particular in relation to treatment of immunological disorders.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: January 5, 2021
    Assignee: NOVO NORDISK A/S
    Inventors: Kristian Kjaergaard, Soeren Lund, Stefan Zahn, Louise H. Zeuthen, Anker J. Hansen
  • Publication number: 20200017599
    Abstract: The present invention concerns human antibodies recognising the human C5a receptor. By binding to C5aR the antibodies inhibit C5a signalling, whereby the pro-inflammatory signal is inhibited. Based on the role of C5a and its receptor in stimulation of inflammation the invention further relates to therapeutic use of said human anti-C5aR antibodies and in particular in relation to treatment of immunological disorders.
    Type: Application
    Filed: June 17, 2019
    Publication date: January 16, 2020
    Inventors: Kristian Kjaergaard, Soeren Lund, Stefan Zahn, Louise H. Zeuthen, Anker J. Hansen
  • Patent number: 10323097
    Abstract: The present invention concerns human antibodies recognizing the human C5a receptor. By binding to C5aR the antibodies inhibit C5a signalling, whereby the pro-inflammatory signal is inhibited. Based on the role of C5a and its receptor in stimulation of inflammation the invention further relates to therapeutic use of said human anti-C5aR antibodies and in particular in relation to treatment of immunological disorders.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: June 18, 2019
    Assignee: Novo Nordisk A/S
    Inventors: Kristian Kjaergaard, Soeren Lund, Stefan Zahn, Louise H. Zeuthen, Anker J. Hansen
  • Patent number: 9708403
    Abstract: The present invention relates to agents and methods that are capable of augmenting NK-mediated killing of target cells by reducing inhibitory KIR signalling without reducing the binding of KIR to HLA-C. As described herein, transduction of negative signaling via KIR, upon binding of KIR to its HLA class I ligand, can involve a ligand-binding induced, conformational reorientation of the KIR molecules allowing interactions to form between adjacent KIRs in specific domains, leading to accelerated clustering. Methods and agents such as monoclonal antibodies for reducing KIR-mediated inhibition of NK cell cytotoxicity without reducing or blocking HLA-binding by, e.g., reducing or blocking dimerization of KIR, are provided.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: July 18, 2017
    Assignees: NOVO NORDISK A/S, INNATE PHARMA
    Inventors: Søren Berg Padkær, Peter Andreas Nicolai Reumert Wagtmann, Petrus Johannes Louis Spee, Stefan Zahn, Kristian Kjærgaard, Anders Svensson
  • Publication number: 20170073421
    Abstract: The present invention concerns human antibodies recognising the human C5a receptor. By binding to C5aR the antibodies inhibit C5a signalling, whereby the pro-inflammatory signal is inhibited. Based on the role of C5a and its receptor in stimulation of inflammation the invention further relates to therapeutic use of said human anti-C5aR antibodies and in particular in relation to treatment of immunological disorders.
    Type: Application
    Filed: November 2, 2016
    Publication date: March 16, 2017
    Inventors: Kristian Kjaergaard, Soeren Lund, Stefan Zahn, Louise H. Zeuthen, Anker J. Hansen
  • Patent number: 9376496
    Abstract: The present invention relates to monoclonal antibodies that are capable of specifically binding to lectin-like transcript 1 (LLT1), to polynucleotides encoding such antibodies, and to cells that express such antibodies. antibodies of the invention have utility in the treatment of autoimmune diseases and cancer, in which LLT1- and CD161-expressing cells play a role in disease pathogenesis.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: June 28, 2016
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Petrus Johannes Louis Spee, Peter Andreas Nicolai Reumert Wagtmann, Stefan Zahn, Elisabeth D. Galsgaard, Birgitte Friedrichsen, Véronique Braud
  • Patent number: D802202
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: November 7, 2017
    Inventor: Karl Stefan Zahn
  • Patent number: D803467
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: November 21, 2017
    Inventor: Karl Stefan Zahn
  • Patent number: D806307
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: December 26, 2017
    Inventor: Karl Stefan Zahn
  • Patent number: D824081
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: July 24, 2018
    Inventor: Karl Stefan Zahn
  • Patent number: D824083
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: July 24, 2018
    Inventor: Karl Stefan Zahn
  • Patent number: D851822
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: June 18, 2019
    Assignee: Lindsey Adelman Studio LLC
    Inventor: Karl Stefan Zahn
  • Patent number: D851823
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: June 18, 2019
    Assignee: Lindsey Adelman Studio LLC
    Inventor: Karl Stefan Zahn
  • Patent number: D851824
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: June 18, 2019
    Assignee: Lindsey Adelman Studio LLC
    Inventor: Karl Stefan Zahn
  • Patent number: D851825
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: June 18, 2019
    Assignee: Lindsey Adelman Studio LLC
    Inventor: Karl Stefan Zahn
  • Patent number: D851826
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: June 18, 2019
    Assignee: Lindsey Adelman Studio LLC
    Inventor: Karl Stefan Zahn
  • Patent number: D852406
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: June 25, 2019
    Assignee: Lindsey Adelman Studio LLC
    Inventor: Karl Stefan Zahn
  • Patent number: D852407
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: June 25, 2019
    Assignee: Lindsey Adelman Studio LLC
    Inventor: Karl Stefan Zahn
  • Patent number: D874047
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: January 28, 2020
    Inventor: Karl Stefan Zahn