Patents by Inventor Stefania Stefanelli

Stefania Stefanelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibiotics GE 23077, pharmaceutically acceptable salts and compositions, and use thereof
    Patent number: 6586393
    Abstract: The invention relates to an antibiotic substance of microbial origin, arbitrarily denominated GE23077 complex and the individual factors which constitute it, a mixture of said factors in any proportion, the pharmaceutically acceptable salts and compositions thereof, and their use as an antibacterial agent having a selective inhibitory activity against E. coli RNA polymerase.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: July 1, 2003
    Assignee: Biosearch Italia S.p.A.
    Inventors: Ismaela Ciciliato, Emiliana Corti, Edoardo Giacomo Sarubbi, Stefania Stefanelli, Nicoletta Montanini, Flavia Marinelli, Michael Kurz, Enrico Selva
  • Antibiotics GE 23077, pharmaceutically acceptable salts and compositions, and use thereof
    Publication number: 20020115597
    Abstract: The invention relates to an antibiotic substance of microbial origin, arbitrarily denominated GE23077 complex and the individual factors which constitute it, a mixture of said factors in any proportion, the pharmaceutically acceptable salts and compositions thereof, and their use as an antibacterial agent having a selective inhibitory activity against E. coli RNA polymerase.
    Type: Application
    Filed: November 9, 2001
    Publication date: August 22, 2002
    Applicant: BIOSEARCH ITALIA S.p.A.
    Inventors: Ismaela Ciciliato, Emiliana Corti, Edoardo Giacomo Sarubbi, Stefania Stefanelli, Nicoletta Montanini, Flavia Marinelli, Michael Kurz, Enrico Selva
  • Use of tropolone derivatives as inhibitors of the enzyme inositol monophosphatase
    Patent number: 5990160
    Abstract: The present invention concerns the use of puberulic or puberulonic acid as inhibitors of the enzyme iositol monophosphatase (EC 3.1.3.25) and thus useful in the treatment of manic or depressive symptoms.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: November 23, 1999
    Assignee: Gruppo Lepetit, SpA
    Inventors: Khalid Islam, Stefania Stefanelli, Federica Sponga, Maurizio Denaro
  • Sesquiteterpenic dervatives
    Patent number: 5854036
    Abstract: The present invention concerns novel compounds obtained by fermenting a microorganism of the genus Memnonoiella or Stachybotrys, which compounds are inhibitors of the enzyme inositol monophosphatase (EC 3.1.3.25). The present invention also relates to the use of these novel compounds in treating manic depression and pharmaceutical formulations comprising said compounds as active ingredient; a further object is the use of these compounds in an analytical method for detecting inositol monophosphatase.
    Type: Grant
    Filed: September 10, 1996
    Date of Patent: December 29, 1998
    Assignee: Gruppo Lepetit S.p.A.
    Inventors: Stefania Stefanelli, Federica Sponga, Khalid Islam, Maurizio Denaro, Pietro Ferrari
  • Anthracycline-conjugates
    Patent number: 5776458
    Abstract: The present invention provides anthracycline conjugates with carriers such as monoclonal polyclonal antibodies, proteins or peptides, or other synthetic carriers. These anthracycline conjugates provide pharmaceutical compositions which are useful for treating certain mammalian tumors. The compounds of the present invention have higher potency than anthracyclines, and improved therapeutic efficacy and reduced toxic effects.
    Type: Grant
    Filed: March 27, 1995
    Date of Patent: July 7, 1998
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Francesco Angelucci, Daniela Ruggieri, Stefania Stefanelli, Antonino Suarato, Laura Bersani
  • New 4'-epi-4'-amino anthracyclines
    Patent number: 5412081
    Abstract: Anthracycline glycosides having the general formula 1 and 2: ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen, fluorine, hydroxy or amino; R.sub.2 and R.sub.3 represent hydroxy or one of R.sub.2 and R.sub.3 is a hydrogen atom, a nitro or an amino group and the other of R.sub.2 and R.sub.3 is a HYDROXY group, exhibit activity against LoVo and LoVo/Dx in vitro.
    Type: Grant
    Filed: January 6, 1993
    Date of Patent: May 2, 1995
    Assignee: Farmitalia Carlo Erba S.R.L.
    Inventors: Francesco Angelucci, Alberto Bargiotti, Daniela Faiardi, Stefania Stefanelli, Antonino Suarato