Patents by Inventor Stefanie Flohr

Stefanie Flohr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use
    Publication number: 20050267038
    Abstract: Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
    Type: Application
    Filed: June 17, 2005
    Publication date: December 1, 2005
    Inventors: Heiner Glombik, Werner Krame, Stefanie Flohr, Wendelin Frick, Hubert Heuer, Gerhard Jaehne, Andreas Lindenschmidt, Hans-Ludwig Schafer
  • Imidazolidine derivatives, their preparation and their use
    Patent number: 6962937
    Abstract: The present invention relates to novel imidazolidine derivatives of the formula I, in which B, E, W, Y, R, R2, R3, R30, e and h have the meanings given herein. The compounds of the formula I are valuable pharmaceutically active compounds which are suitable, for example, for treating inflammatory diseases, for example, rheumatoid arthritis, or allergic diseases. The compounds of the formula I are inhibitors of the adhesion and migration of leukocytes and/or antagonists of the adhesion receptor VLA-4, which belongs to the integrin group. They are generally suitable for treating diseases which are caused by, or associated with, an undesirable degree of leukocyte adhesion and/or leukocyte migration or in which cell-cell or cell-matrix interactions, which are based on the interactions of VLA-4 receptors with their ligands, play a role.
    Type: Grant
    Filed: July 31, 2002
    Date of Patent: November 8, 2005
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Volkmar Wehner, Stefanie Flohr, Horst Blum, Hartmut Rütten, Hans Ulrich Stilz
  • Nitrogen-substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives, processes for their preparation and their use as medicaments
    Publication number: 20050085483
    Abstract: Nitrogen-substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives, processes for the preparation and their use as medicaments The invention relates to substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof. in which the radicals have the stated meanings, and the physiologically tolerated salts thereof and processes for preparing them are described. The compounds are suitable for example as anorectic agents.
    Type: Application
    Filed: February 13, 2004
    Publication date: April 21, 2005
    Applicant: AVENTIS PHARMA DEUTSCHLAND GMBH
    Inventors: Stefanie Flohr, Siegfried Stengelin, Matthias Gossel, Thomas Klabunde, Petra Stahl, Pavel Safar, James Spoonamore, Martin Smrcina, Joseph Klein, Gregory Merriman, Brian Whiteley, Carolina Lanter, Kenneth Bordeau, Zhaoxia Yang
  • Nover diphenylazetidinone with improved physiological properties, process for its preparation, medicaments comprising this compound, and its use
    Publication number: 20050020563
    Abstract: The invention relates to the compound of the formula 1 and to its physiologically acceptable salts. The compound is suitable, for example, as a hypolipidemic.
    Type: Application
    Filed: March 31, 2004
    Publication date: January 27, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jaehne, Wendelin Frick, Andreas Lindenschmidt, Stefanie Flohr, Hubert Heuer, Hans-Ludwig Schaefer, Werner Kramer, Eric Galia, Heiner Glombik
  • Pyrazoloisoquinoline derivatives for inhibiting NF?B-inducing kinase
    Patent number: 6841556
    Abstract: Compounds of the formula I are suitable for producing pharmaceuticals for the prophylaxis and therapy of diseases whose course involves an increased activity of NIK.
    Type: Grant
    Filed: July 3, 2003
    Date of Patent: January 11, 2005
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Stefanie Flohr, Thorsten Naumann
  • Substituted hexahydropyrazino (1,2-a) pyrimidine-4,7-dione derivatives, processes for their preparation and their use as medicaments
    Publication number: 20050004131
    Abstract: Substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives, processes for their preparation and their use as medicaments The invention relates to substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof. Compounds of the formula I in which the radicals have the stated meanings, and the physiologically tolerated salts thereof and processes for preparing them are described. The compounds are suitable for example as anorectic agents.
    Type: Application
    Filed: February 13, 2004
    Publication date: January 6, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Stefanie Flohr, Siegfried Stengelin, Matthias Gossel, Thomas Klabunde
  • Pyrazoloisoquinoline derivatives for inhibiting NFkappaB-inducing kinase
    Publication number: 20040097541
    Abstract: Compounds of the formula I 1
    Type: Application
    Filed: July 3, 2003
    Publication date: May 20, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Stefanie Flohr, Thorsten Naumann
  • Ring -substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
    Publication number: 20040082561
    Abstract: One embodiment of the invention relates to compounds of the formula I, 1
    Type: Application
    Filed: June 18, 2003
    Publication date: April 29, 2004
    Inventors: Gerhard Jaehne, Wendelin Frick, Stefanie Flohr, Andreas Lindenschmidt, Heiner Glombik, Werner Kramer, Hubert Heuer, Hans-Ludwig Schaefer
  • Cationically substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
    Publication number: 20040077623
    Abstract: One embodiment of the invention relates to compounds of the formula I, 1
    Type: Application
    Filed: June 18, 2003
    Publication date: April 22, 2004
    Inventors: Gerhard Jaehne, Wendelin Frick, Stefanie Flohr, Andreas Lindenschmidt, Heiner Glombik, Werner Kramer, Hubert Heuer, Hans-Ludwig Schaefer
  • Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
    Publication number: 20040067913
    Abstract: One embodiment of the invention relates to compounds of the formula I: 1
    Type: Application
    Filed: June 18, 2003
    Publication date: April 8, 2004
    Inventors: Gerhard Jaehne, Wendelin Frick, Stefanie Flohr, Andreas Lindenschmidt, Heiner Glombik, Werner Kramer, Hubert Heuer, Hans-Ludwig Schaefer
  • Diphenylazetidinone derivatives, process for their preparation, medicaments comprising these compounds and their use
    Patent number: 6703386
    Abstract: Compounds of the formula I, for example, are disclosed, in which R1, R2, R3, R4, R5, and R6 independently of one another are (C0-C30)-alkylene-L or are the meanings given in the description, and where L is shown connected to (C0-C30)-alkylene as follows: where Rx, Ry, Rz have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: March 9, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heiner Glombik, Werner Kramer, Stefanie Flohr, Wendelin Frick, Hubert Heuer, Gerhard Jaehne, Andreas Lindenschmidt, Hans-Ludwig Schaefer
  • Novel imidazolidine derivatives, their preparation and their use
    Publication number: 20030109497
    Abstract: The present invention relates to novel imidazolidine derivatives of the formula I, 1
    Type: Application
    Filed: July 31, 2002
    Publication date: June 12, 2003
    Inventors: Volkmar Wehner, Stefanie Flohr, Horst Blum, Hartmut Rutten, Hans Ulrich Stilz
  • Diphenylazetidinone derivatives, process for their preparation, medicaments comprising these compounds and their use
    Patent number: 6498156
    Abstract: Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: December 24, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heiner Glombik, Werner Kramer, Stefanie Flohr, Wendelin Frick, Hubert Heuer, Gerhard Jaehne, Andreas Lindenschmidt, Hans-Ludwig Schaefer
  • Novel diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use
    Publication number: 20020137689
    Abstract: Compounds of the formula I, 1
    Type: Application
    Filed: December 19, 2001
    Publication date: September 26, 2002
    Inventors: Heiner Glombik, Werner Krame, Stefanie Flohr, Wendelin Frick, Hubert Heuer, Gerhard Jaehne, Andreas Lindenschmidt, Hans-Ludwig Schafer
  • Diphenylazetidinone derivatives, process for their preparation, medicaments comprising these compounds and their use
    Publication number: 20020128252
    Abstract: Compounds of the formula I, 1
    Type: Application
    Filed: December 19, 2001
    Publication date: September 12, 2002
    Inventors: Heiner Glombik, Werner Kramer, Stefanie Flohr, Wendelin Frick, Hubert Heuer, Gerhard Jaehne, Andreas Lindenschmidt, Hans-Ludwig Schafer
  • Diphenylazetidinone derivatives, process for their preparation, medicaments comprising these compounds and their use
    Publication number: 20020128253
    Abstract: Compounds of the formula I, 1
    Type: Application
    Filed: December 19, 2001
    Publication date: September 12, 2002
    Inventors: Heiner Glombik, Werner Kramer, Stefanie Flohr, Wendelin Frick, Hubert Heuer, Gerhard Jaehne, Andreas Lindenschmidt, Hans-Ludwig Schaefer