Patents by Inventor Stefanie GEISSLER

Stefanie GEISSLER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of bacterial glutaminyl cyclases for use in the treatment of periodontal and related diseases
    Patent number: 11958871
    Abstract: The present invention relates to novel compounds which are particularly useful as inhibitors of bacterial glutaminyl cyclases (bacQC); pharmaceutical compositions comprising such compounds; compounds and/or pharmaceutical compositions for use in methods for treatment, in particular for use in the treatment of periodontitis and related conditions; as well as to crystals comprising bacterial glutaminyl cyclases, methods for identifying candidate compounds which may associate with the binding pocket of a bacQC and/or are bacQC inhibitors.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: April 16, 2024
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Christian Jäger, Linda Liebe, Daniel Ramsbeck, Miriam Linnert, Stefanie Geissler, Anke Piechotta, Diane Meitzner, Holger Cynis, Mirko Buchholz
  • NOVEL INHIBITORS OF BACTERIAL GLUTAMINYL CYCLASES FOR USE IN THE TREATMENT OF PERIODONTAL AND RELATED DISEASES
    Publication number: 20200392174
    Abstract: The present invention relates to novel compounds which are particularly useful as inhibitors of bacterial glutaminyl cyclases (bacQC); pharmaceutical compositions comprising such compounds; compounds and/or pharmaceutical compositions for use in methods for treatment, in particular for use in the treatment of periodontitis and related conditions; as well as to crystals comprising bacterial glutaminyl cyclases, methods for identifying candidate compounds which may associate with the binding pocket of a bacQC and/or are bacQC inhibitors.
    Type: Application
    Filed: February 22, 2019
    Publication date: December 17, 2020
    Inventors: Christian JÄGER, Linda LIEBE, Daniel RAMSBECK, Miriam LINNERT, Stefanie GEISSLER, Anke PIECHOTTA, Diane MEITZNER, Holger CYNIS, Mirko BUCHHOLZ