Patents by Inventor Stefanie Grabulovski

Stefanie Grabulovski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies Against IL-1 Beta
    Publication number: 20230203151
    Abstract: The present invention relates to anti-IL-1 beta antibodies and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable. Such antibodies can be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Application
    Filed: August 5, 2022
    Publication date: June 29, 2023
    Applicant: Cell Medica, Inc.
    Inventors: Annemarie HONEGGER, Titus KRETZSCHMAR, Simone SCHMITT, Abdijapar SHAMSHIEV, Stefanie GRABULOVSKI
  • Nucleic acids encoding antibodies against IL-1 beta
    Patent number: 11407824
    Abstract: The present invention relates to anti-IL-1 beta antibodies and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable. Such antibodies can be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: August 9, 2022
    Assignee: Cell Medica, Inc.
    Inventors: Annemarie Honegger, Titus Kretzschmar, Simone Schmitt, Abdijapar Shamshiev, Stefanie Grabulovski
  • ANTIBODY TO HUMAN IL-1 BETA
    Publication number: 20220220195
    Abstract: The present invention relates to anti-IL-1 beta binding members and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable and soluble. Such binding members may be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Application
    Filed: January 28, 2022
    Publication date: July 14, 2022
    Inventors: Stefanie Grabulovski, Titus KRETZSCHMAR, Simone SCHMITT, Abdijapar SHAMSHIEV, Thorsten Alexander SCHAFER
  • Antibody to human IL-1 beta
    Patent number: 11267884
    Abstract: The present invention relates to anti-IL-1 beta binding members and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable and soluble. Such binding members may be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: March 8, 2022
    Assignee: Cell Medica Inc.
    Inventors: Stefanie Grabulovski, Titus Kretzschmar, Simone Schmitt, Abdijapar Shamshiev, Thorsten Alexander Schafer
  • ANTIBODIES AGAINST IL-1 BETA
    Publication number: 20200362028
    Abstract: The present invention relates to anti-IL-1 beta antibodies and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable. Such antibodies can be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Application
    Filed: February 6, 2020
    Publication date: November 19, 2020
    Inventors: Annemarie Honegger, Titus Kretzschmar, Simone Schmitt, Abdijapar Shamshiev, Stefanie Grabulovski
  • ANTIBODY TO HUMAN IL-1 BETA
    Publication number: 20200239565
    Abstract: The present invention relates to anti-IL-1 beta binding members and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable and soluble. Such binding members may be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Application
    Filed: March 18, 2020
    Publication date: July 30, 2020
    Inventors: Stefanie GRABULOVSKI, Titus KRETZSCHMAR, Simone SCHMITT, Abdijapar SHAMSHIEV, Thorsten Alexander SCHAFER
  • Nucleic acid encoding antibody to human IL-1 beta
    Patent number: 10626171
    Abstract: The present invention relates to anti-IL-1 beta binding members and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable and soluble. Such binding members may be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: April 21, 2020
    Assignee: Cell Medica Switzerland AG
    Inventors: Stefanie Grabulovski, Titus Kretzschmar, Simone Schmitt, Abdijapar Shamshiev, Thorsten Alexander Schafer
  • ANTIBODY TO HUMAN IL-1 BETA
    Publication number: 20180362642
    Abstract: The present invention relates to anti-IL-1 beta binding members and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable and soluble. Such binding members may be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Application
    Filed: August 30, 2018
    Publication date: December 20, 2018
    Inventors: Stefanie Grabulovski, Titus Kretzschmar, Simone Schmitt, Abdijapar Shamshiev, Thorsten Alexander Schafer
  • Method of inhibiting human IL-1 beta by administering an antibody to human IL-1 beta
    Patent number: 10077302
    Abstract: The present invention relates to anti-IL-1 beta binding members and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable and soluble. Such binding members may be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: September 18, 2018
    Assignee: Cell Medica Switzerland AG
    Inventors: Stefanie Grabulovski, Titus Kretzschmar, Simone Schmitt, Abdijapar Shamshiev, Thorsten Alexander Schafer
  • ANTIBODIES AGAINST IL-1 BETA
    Publication number: 20180258165
    Abstract: The present invention relates to anti-IL-1 beta antibodies and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable. Such antibodies can be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Application
    Filed: February 14, 2018
    Publication date: September 13, 2018
    Inventors: Annemarie Honegger, Titus Kretzschmar, Simone Schmitt, Abdijapar Shamshiev, Stefanie Grabulovski
  • Antibodies against IL-1 beta
    Patent number: 9914772
    Abstract: The present invention relates to anti-IL-1 beta antibodies and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable. Such antibodies can be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: March 13, 2018
    Assignee: Cell Medica Switzerland AG
    Inventors: Annemarie Honegger, Titus Kretzschmar, Simone Schmitt, Abdijapar Shamshiev, Stefanie Grabulovski
  • Antibody to Human IL-1 Beta
    Publication number: 20170051054
    Abstract: The present invention relates to anti-IL-1 beta binding members and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable and soluble. Such binding members may be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Application
    Filed: July 6, 2016
    Publication date: February 23, 2017
    Inventors: Stefanie GRABULOVSKI, Titus KRETZSCHMAR, Simone SCHMITT, Abdijapar SHAMSHIEV, Thorsten Alexander SCHAFER
  • Antibody to human IL-1 beta
    Patent number: 9404930
    Abstract: The present invention relates to anti-IL-1 beta binding members and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable and soluble. Such binding members may be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: August 2, 2016
    Assignee: DELENEX THERAPEUTICS AG
    Inventors: Stefanie Grabulovski, Titus Kretzschmar, Simone Schmitt, Abdijapar Shamshiev, Thorsten Alexander Schäfer
  • ANTIBODIES AGAINST IL-1 BETA
    Publication number: 20160194392
    Abstract: The present invention relates to anti-IL-1 beta antibodies and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable. Such antibodies can be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Application
    Filed: June 16, 2015
    Publication date: July 7, 2016
    Inventors: Annemarie Honegger, Titus Kretzschmar, Simone Schmitt, Abdijapar Shamshiev, Stefanie Grabulovski
  • BINDING MEMBERS TO IL-1 BETA
    Publication number: 20140134183
    Abstract: The present invention relates to anti-IL-1 beta binding members and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable and soluble. Such binding members may be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
    Type: Application
    Filed: November 5, 2013
    Publication date: May 15, 2014
    Applicant: Delenex Therapeutics AG
    Inventors: Stefanie Grabulovski, Titus Kretzschmar, Simone Schmitt, Abdijapar Shamshiev