Patents by Inventor Stefanie Grosskopf

Stefanie Grosskopf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Shp-2 inhibitors and pharmaceutical compositions comprising them
    Patent number: 7868185
    Abstract: The present invention relates to small molecule protein tyrosine phosphatase inhibitors, especially Shp-2 inhibitors, of formula (I) and/or (II), and to pharmaceutical compositions comprising them. The invention is also directed to the use of said compounds for the treatment of phosphatase-mediated diseases, especially cancer and metastasis. The invention further concerns a method for treating a proliferative disease, a genetic disorder, an autoimmune disease, an angiogenic disorder or cancer in a patient in need of such treatment, comprising administering to said patient a therapeutically effective amount of at least one compound of formula (I) and/or (II).
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: January 11, 2011
    Assignees: Max-Delbruck-Centrum fur Molekulare Medizin, Forschungsverbund Berlin E, V.
    Inventors: Klaus Hellmuth, Walter Birchmeier, Joerg Rademann, Stefanie Grosskopf
  • Shp-2 Inhibitors, Pharmaceutical Compositons Comprising Them and Their Use For Treating Phosphatase-Mediated Diseases
    Publication number: 20080194563
    Abstract: The present invention relates to small molecule protein tyrosine phosphatase inhibitors, especially Shp-2 inhibitors, of formula (I) and/or (II), and to pharmaceutical compositions comprising them. The invention is also directed to the use of said compounds for the treatment of phosphatase-mediated diseases, especially cancer and metastasis. The invention further concerns a method for treating a proliferative disease, a genetic disorder, an autoimmune disease, an angiogenic disorder or cancer in a patient in need of such treatment, comprising administering to said patient a therapeutically effective amount of at least one compound of formula (I) and/or (II).
    Type: Application
    Filed: June 1, 2006
    Publication date: August 14, 2008
    Inventors: Klaus Hellmuth, Walter Birchmeier, Joerg Rademann, Stefanie Grosskopf