Patents by Inventor Stefano Bompadre

Stefano Bompadre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to Assay Coenzzyme Q10 in Blood Plasma or Blood Serum
    Publication number: 20080090265
    Abstract: A method is described for determining CoQ10 concentrations in plasma samples. CoQ10 in the plasma sample is oxidized by treating the sample with an oxidizing agent having a redox potential higher than the redox potential of COQ10, such as, for example, para-benzoquinone. Following oxidation of the COQ10, the CoQ10 in the plasma sample is extracted with an alcohol, such as, for example, 1-propanol. The alcohol extract is analyzed using direct injection into the HPLC apparatus. This method achieves a rapid, accurate analysis of plasma CoQ10 levels, which can be used for monitoring the bioavailability of orally administered CoQ10 used as a food supplement or as an adjunctive therapy.
    Type: Application
    Filed: December 3, 2007
    Publication date: April 17, 2008
    Inventors: Gian Littarru, Fabrizo Mosca, Daniele Fattorini, Stefano Bompadre
  • Method to assay coenzyme Qin blood plasma or blood serum
    Patent number: 7303921
    Abstract: A method is described for determining CoQ10 concentrations in plasma samples. CoQ10 in the plasma sample is oxidized by treating the sample with an oxidizing agent having a redox potential higher than the redox potential of CoQ10, such as, for example, para-benzoquinone. Following oxidation of the CoQ10, the CoQ10 in the plasma sample is extracted with an alcohol, such as, for example, 1-propanol. The alcohol extract is analyzed using direct injection into the HPLC apparatus. This method achieves a rapid, accurate analysis of plasma CoQ10 levels, which can be used for monitoring the bioavailability of orally administered CoQ10 used as a food supplement or as an adjunctive therapy.
    Type: Grant
    Filed: May 23, 2003
    Date of Patent: December 4, 2007
    Inventors: Gian Paolo Littarru, Fabrizo Mosca, Daniele Fattorini, Stefano Bompadre
  • Method to assay coenzyme Q10 in blood plasma or blood serum
    Publication number: 20040033553
    Abstract: A method is described for determining CoQ10 concentrations in plasma samples. CoQ10 in the plasma sample is oxidized by treating the sample with an oxidizing agent having a redox potential higher than the redox potential of CoQ10, such as, for example, para-benzoquinone. Following oxidation of the CoQ10, the CoQ10 in the plasma sample is extracted with an alcohol, such as, for example, 1-propanol. The alcohol extract is analyzed using direct injection into the HPLC apparatus. This method achieves a rapid, accurate analysis of plasma CoQ10 levels, which can be used for monitoring the bioavailability of orally administered CoQ10 used as a food supplement or as an adjunctive therapy.
    Type: Application
    Filed: May 23, 2003
    Publication date: February 19, 2004
    Inventors: Gian Paolo Littarru, Fabrizio Mosca, Daniele Fattorini, Stefano Bompadre