Patents by Inventor Stefano Fiore

Stefano Fiore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING PAIN IN SUBJECTS WITH RHEUMATOID ARTHRITIS
    Publication number: 20250333522
    Abstract: The present disclosure relates to the use of an anti-IL6 receptor antibody for treating unacceptable pain in subjects with rheumatoid arthritis. Subjects with unacceptable pain can have, e.g., refractory pain or strict refractory pain.
    Type: Application
    Filed: April 10, 2025
    Publication date: October 30, 2025
    Inventors: Susan Boklage, Toshio Kimura, Stefano Fiore, Gregory St John, Wenhui Wei, Vivian Bykerk
  • Compositions and methods for treating pain in subjects with rheumatoid arthritis
    Patent number: 12297279
    Abstract: The present disclosure relates to the use of an anti-IL6 receptor antibody for treating unacceptable pain in subjects with rheumatoid arthritis. Subjects with unacceptable pain can have, e.g., refractory pain or strict refractory pain.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: May 13, 2025
    Assignees: SANOFI BIOTECHNOLOGY, REGENERON PHARMACEUTICALS, INC.
    Inventors: Susan Boklage, Toshio Kimura, Stefano Fiore, Gregory St John, Wenhui Wei, Vivian Bykerk
  • COMPOSITIONS AND METHODS FOR TREATING POLYMYALGIA RHEUMATICA BY ADMINISTERING AN IL-6R ANTAGONIST
    Publication number: 20230399410
    Abstract: The present disclosure relates to the use of an anti-IL6 receptor antibody, or an antigen-binding fragment thereof, for treating polymyalgia rheumatica (PMR).
    Type: Application
    Filed: April 5, 2023
    Publication date: December 14, 2023
    Inventors: Jennifer SLOANE LAZAR, Yong LIN, Wanling WONG, Ying LIU, Frédéric MARRACHE, Kerri FORD, Stefano FIORE, Lita ARAUJO, Danielle ISAMAN, Jeffrey CURTIS, Chad NIVENS, Bola AKINLADE, Angeliki GIANNELOU
  • COMPOSITIONS AND METHODS FOR TREATING JUVENILE IDIOPATHIC ARTHRITIS
    Publication number: 20230127528
    Abstract: The present disclosure provides compositions and methods of treating and improving the symptoms of systemic juvenile idiopathic arthritis and polyarticular-course juvenile idiopathic arthritis using an antibody that specifically binds human interleukin-6 receptor (hIL-6R).
    Type: Application
    Filed: September 22, 2022
    Publication date: April 27, 2023
    Inventors: Lydie Baret-Cormel, Tanya Momtahen, Stefano Fiore, Janet Van Adelsberg
  • Compositions and methods for treating juvenile idiopathic arthritis
    Patent number: 11498969
    Abstract: The present disclosure provides compositions and methods of treating and improving the symptoms of systemic juvenile idiopathic arthritis and polyarticular-course juvenile idiopathic arthritis using an antibody that specifically binds human interleukin-6 receptor (hIL-6R).
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: November 15, 2022
    Assignees: SANOFI BIOTECHNOLOGY, REGENERON PHARMACEUTICALS, INC.
    Inventors: Lydie Baret-Cormel, Tanya Momtahen, Stefano Fiore, Janet Van Adelsberg
  • COMPOSITIONS AND METHODS FOR TREATING PAIN IN SUBJECTS WITH RHEUMATOID ARTHRITIS
    Publication number: 20200399380
    Abstract: The present disclosure relates to the use of an anti-IL6 receptor antibody for treating unacceptable pain in subjects with rheumatoid arthritis. Subjects with unacceptable pain can have, e.g., refractory pain or strict refractory pain.
    Type: Application
    Filed: June 3, 2020
    Publication date: December 24, 2020
    Inventors: Susan Boklage, Toshio Kimura, Stefano Fiore, Gregory St John, Wenhui Wei, Vivian Bykerk
  • COMPOSITIONS AND METHODS FOR TREATING JUVENILE IDIOPATHIC ARTHRITIS
    Publication number: 20200339693
    Abstract: The present disclosure provides compositions and methods of treating and improving the symptoms of systemic juvenile idiopathic arthritis and polyarticular-course juvenile idiopathic arthritis using an antibody that specifically binds human interleukin-6 receptor (hIL-6R).
    Type: Application
    Filed: January 31, 2020
    Publication date: October 29, 2020
    Inventors: Lydie Baret-Cormel, Tanya Momtahen, Stefano Fiore, Janet Van Adelsberg
  • COMPOSITIONS FOR THE TREATMENT OF RHEUMATOID ARTHRITIS AND METHODS OF USING SAME
    Publication number: 20160280782
    Abstract: The present invention provides compositions and methods of treating and improving the symptoms of rheumatoid arthritis using an antibody that specifically binds human interleukin-6 receptor (hIL-6R).
    Type: Application
    Filed: November 21, 2014
    Publication date: September 29, 2016
    Inventors: Xiaohong Huang, Martine Jasson, Vanessa Marks, Allen Radin, Chungpeng Fan, Hubert Van Hoogstraten, Stefano Fiore, Janet Van Adelsberg, Mark Genovese
  • Immunoglobulin having particular framework scaffold and methods of making and using
    Publication number: 20050037420
    Abstract: This invention relates to immunoglobulin molecules comprising light chain (VL) chimeric variable domains, heavy chain (VH) chimeric variable domains, e.g., scFv antibodies that are expressed at high levels within a host cell, preferably within particular cellular compartments such as, e.g., cytosol or apoplast. The VL, VH and scFv antibody molecules comprise framework scaffolds of particularly preferred framework regions. This invention also relates to nucleic acid molecules encoding the immunoglobulin molecules of this invention, vectors expressing the immunoglobulin molecules, hosts transformed with the nucleic acid molecules and vectors, and methods of using the immunoglobulin molecules. Also described are immunoglobulin libraries as well as host cells, including transgenic plants, expressing the VL, VH or scFv antibody molecules of this invention.
    Type: Application
    Filed: September 13, 2002
    Publication date: February 17, 2005
    Inventors: Mei-Yun Zhang, Stefan Schillberg, Sabine Zimmermann, Stefano Fiore, Neil Emans, Rainer Fischer