Patents by Inventor Stefano LEVANTO

Stefano LEVANTO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrahydrothieno pyridine derivatives as DDRs inhibitors
    Patent number: 12723052
    Abstract: The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.
    Type: Grant
    Filed: March 25, 2022
    Date of Patent: September 1, 2026
    Assignee: CHIESI FARMACEUTICI S.P.A.
    Inventors: Laura Carzaniga, Andrea Rizzi, Nicolò Iotti, Fabio Rancati, Anna Karawajczyk, Barbara Karolina Wołek, David Edward Clark, Toby Matthew Grover Mullins, Keith Christopher Knight, Ben Paul Whittaker, Stefano Levanto
  • HETEROARYL DERIVATIVES AS DDRs INHIBITORS
    Publication number: 20260242353
    Abstract: The present invention relates to compounds of formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, intermediate compounds useful in such preparations, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.
    Type: Application
    Filed: July 18, 2023
    Publication date: August 20, 2026
    Applicant: CHIESI FARMACEUTICI S.P.A.
    Inventors: Roberta MAZZUCATO, Nicolò IOTTI, Laura CARZANIGA, Andrea RIZZI, Eleonora GHIDINI, Stefano LEVANTO, Benjamin Paul WHITTAKER, David Edward CLARK, Paolo RONCHI
  • PYRROLIDINE DERIVATIVES AS DDRS INHIBITORS
    Publication number: 20240425482
    Abstract: The present invention relates to compounds of formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, intermediate compounds useful in such preparations, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.
    Type: Application
    Filed: October 17, 2022
    Publication date: December 26, 2024
    Applicant: CHIESI FARMACEUTICI S.P.A.
    Inventors: Laura CARZANIGA, Fabio RANCATI, Andrea RIZZI, Eleonora GHIDINI, Nicolò IOTTI, Roberta MAZZUCATO, Stefano LEVANTO, Ben Paul WHITTAKER
  • TETRAHYDROTHIENO PYRIDINE DERIVATIVES AS DDRS INHIBITORS
    Publication number: 20240391936
    Abstract: The present invention relates to compounds of general formula (I) inhibiting Discoidin Domain Receptors (DDR inhibitors), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful for instance in the treatment of many disorders associated with DDR mechanisms.
    Type: Application
    Filed: March 25, 2022
    Publication date: November 28, 2024
    Applicant: CHIESI FARMACEUTICI S.P.A.
    Inventors: Laura CARZANIGA, Andrea RIZZI, Nicoió IOTTI, Fabio RANCATI, Anna KARAWAJCZYK, Barbara Karolina WOLEK, David Edward CLARK, Toby Matthew Grover MULLINS, Keith Christopher KNIGHT, Ben Paul WHITTAKER, Stefano LEVANTO
  • RESCORCINOLS, METHODS FOR THEIR MANUFACTURE, AND USES THEREOF
    Publication number: 20240254066
    Abstract: The present invention relates to a group of resorcinol derivatives as a pharmaceutically active compounds and methods of preparation thereof. Resorcinol derivatives have been used to treat various diseases and disorders. While such treatments hold promise, there remains a need in the art for more effective treatments and this has been brought about by way of the resorcinol derivative of the invention.
    Type: Application
    Filed: May 12, 2022
    Publication date: August 1, 2024
    Inventors: Alan James SILCOCK, Karen Ka-Yen TSE, Paul Stuart HINCHLIFFE, Andrew SHARPE, Iain David SIMPSON, Joanne PEACH, Stefano LEVANTO, Antoine MILLET, Inderjit Singh MANN
  • CANNABINOID DERIVATIVES AS PHARMACEUTICALLY ACTIVE COMPOUNDS AND METHOD OF PREPARATION THEREOF
    Publication number: 20240025858
    Abstract: The present invention relates to a group of novel compounds, methods for their manufacture and the use of these compounds as research tools and as pharmaceuticals. The novel compounds are analogues of cannabidiol (CBD). CBD is a non-psychoactive cannabinoid which has been used to treat various diseases and disorders. While such treatments hold promise, there remains a need in the art for more effective treatments and this has been brought about by way of novel cannabidiol compounds.
    Type: Application
    Filed: December 15, 2021
    Publication date: January 25, 2024
    Inventors: Alan James SILCOCK, Antoine MILLET, Karen Ka-Yen TSE, Paul Stuart HINCHLIFFE, Andrew SHARPE, Iain David SIMPSON, Joanne PEACH, Stefano LEVANTO
  • COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF
    Publication number: 20230212131
    Abstract: The present invention relates to novel Collagen 1 translation inhibitors, composition and methods of preparation thereof, and uses thereof for treating Fibrosis including lung, liver, kidney, cardiac and dermal fibrosis, IPF, wound healing, scarring and Gingival fibromatosis, Systemic Sclerosis, and alcoholic and non-alcoholic steatohepatitis (NASH).
    Type: Application
    Filed: June 9, 2021
    Publication date: July 6, 2023
    Applicant: Anima Biotech Inc.
    Inventors: David William SHEPPARD, Jason Paul TIERNEY, Aviad MANDABI, Wolfgang SCHMIDT, Stefano LEVANTO, Julie Nicole HAMBLIN, Richard James BULL, Iris ALROY, Wissam MANSOUR, Moty KLEPFISH, Yaode WANG, Haitang LI
  • COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF
    Publication number: 20230150980
    Abstract: The present invention relates to novel Collagen I translation inhibitors, composition and methods of preparation thereof, and uses thereof for treating Fibrosis including lung, liver, kidney, cardiac and dermal fibrosis, IPF, wound healing, scarring and Gingival fibromatosis, Systemic Sclerosis, and alcoholic and non-alcoholic steatohepatitis (NASH).
    Type: Application
    Filed: April 21, 2021
    Publication date: May 18, 2023
    Applicant: Anima Biotech Inc.
    Inventors: David William SHEPPARD, Jason Paul TIERNEY, Aviad MANDABI, Wolfgang SCHMIDT, Stefano LEVANTO, Julie Nicole HAMBLIN, Richard James BULL, Iris ALROY, Wissam MANSOUR, Moty KLEPFISH, Yaode WANG, Haitang Ll, Stephen David PENROSE
  • ENZYME INHIBITORS
    Publication number: 20220298138
    Abstract: The present invention provides compounds of formula (I): Formula (I) compositions comprising such compounds; the use of such compounds in therapy; and methods of treating patients with such compounds; wherein A, Y, n, R1, R2A, R2B, R3 and *1 are as defined herein.
    Type: Application
    Filed: August 21, 2019
    Publication date: September 22, 2022
    Inventors: Rebecca Louise DAVIE, Hannah Joy EDWARDS, David Michael EVANS, Simon Teanby HODGSON, Sally Louise MARSH, Alessandro MAZZACANI, David Philip ROOKER, Michael John STOCKS, Andrew Peter CRIDLAND, Emanuela GANCIA, Julie Nicole HAMBLIN, Paul Stuart HINCHLIFFE, Stefano LEVANTO, Terence Aaron PANCHAL, Iain Robert MILLER