Abstract: A system for the deposition of microparticles comprises at least one launch unit configured to individually accelerate and convey a succession of microparticles in the direction of a work surface. The launch unit has a tubular shape defining a flow channel for the succession of microparticles and extends preferably linearly between an inlet end interfaceable with a device for feeding microparticles and an outlet end which can face the work surface. The launch unit comprises a charging portion, proximal to the inlet end, configured to generate an electric field of electrification adapted to electrically charge the succession of microparticles and an acceleration portion, proximal to the outlet end, configured to generate an electric field of acceleration adapted to accelerate the succession of microparticles towards the outlet end.

Abstract: Method for setting up a tyre checking apparatus, said apparatus (1) comprising at least: a support base (34) for a tyre (2); a first acquisition device (430) and a second acquisition device (43a) for acquiring images representative of said tyre (2) positioned on said support base (34); a first robotic member (40a) for moving said second acquisition device (43a). Said method comprises: providing a setup device (100) comprising: a first wall (110) having first predefined shapes (F1); a second wall (120) having second predefined shapes (F2), said second wall (120) being substantially parallel and non-coplanar to said first wall (110); a top surface (130); a central reference (140) arranged on said top surface (130). Said method also comprises: executing at least one of a first set-up and a second set-up.

Abstract: Method for setting up a tyre checking apparatus, said apparatus (1) comprising at least: a support base (34) for a tyre (2); a first acquisition device (430) and a second acquisition device (43a) for acquiring images representative of said tyre (2) positioned on said support base (34); a first robotic member (40a) for moving said second acquisition device (43a). Said method comprises: providing a setup device (100) comprising: a first wall (110) having first predefined shapes (F1); a second wall (120) having second predefined shapes (F2), said second wall (120) being substantially parallel and non-coplanar to said first wall (110); a top surface (130); a central reference (140) arranged on said top surface (130). Said method also comprises: executing at least one of a first set-up and a second set-up.

Abstract: Method for setting up a tyre checking apparatus, said apparatus (1) comprising at least: a support base (34) for a tyre (2) a first acquisition device (430) and a second acquisition device (43a) for acquiring images representative of said tyre (2) positioned on said support base (34); a first robotic member (40a) for moving said second acquisition device (43a). Said method comprises: providing a setup device (100) comprising: a first wall (110) having first predefined shapes (F1); a second wall (120) having second predefined shapes (F2), said second wall (120) being substantially parallel and non-coplanar to said first wall (110); a top surface (130); a central reference (140) arranged on said top surface (130). Said method also comprises: executing at least one of a first set-up and a second set-up.

Abstract: Disclosed are methods and reagents for diagnosis, classification and treatment of DLBCL and subtypes thereof by means of gene expression profiling. Provided herein is a gene expression signature for use in obtaining diagnostic information for DLBCL and subtypes thereof. Aspects of the present disclosure relate to use of gene expression signature corresponding to particular subtype for classification of a sample from a subject and stratification of a subject for subtype-targeted clinical trial. Also provided herein is a computer based classification model for use in the methods disclosed herein.

Abstract: Method for setting up a tyre checking apparatus, said apparatus (1) comprising at least: a support base (34) for a tyre (2) a first acquisition device (430) and a second acquisition device (43a) for acquiring images representative of said tyre (2) positioned on said support base (34); a first robotic member (40a) for moving said second acquisition device (43a). Said method comprises: providing a setup device (100) comprising : a first wall (110) having first predefined shapes (F1); a second wall (120) having second predefined shapes (F2), said second wall (120) being substantially parallel and non-coplanar to said first wall (110); a top surface (130); a central reference (140) arranged on said top surface (130). Said method also comprises: executing at least one of a first set-up and a second set-up.

Abstract: A method and apparatus for detecting defects on tires in a tire production process. The method includes: receiving a reference image of a surface portion of a reference tire substantially defects-free; providing a sample tire to be analyzed; illuminating a surface portion of the sample tire with a raking light source; acquiring a sample image of the illuminated surface portion of the sample tire; extracting the edges from the reference image and from the sample image and respectively generating an edge reference image and an edge sample image; carrying out a dilation of the edges of the edge reference image and generating therefrom a dilated edge reference image; comparing the edge sample image with respect to the dilated edge reference image and generating an edge image of possible defects; and identifying the edges in the edge image of possible defects.

Abstract: The present invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating cancer (e.g., hematological malignancies in humans). A variety of biomarker chromosomal number alterations (CNAs) and biomarkers corresponding thereto, are provided, wherein alterations in the copy number of one or more of the biomarker CNAs and/or alterations in the amount, structure, and/or activity of one or more of the biomarkers comprised within the CNAs is associated with cancer status.

Abstract: A method and apparatus for detecting defects on tyres in a tyre production process. The method includes: receiving a reference image of a surface portion of a reference tyre substantially defects-free; providing a sample tyre to be analysed; illuminating a surface portion of the sample tyre with a raking light source; acquiring a sample image of the illuminated surface portion of the sample tyre; extracting the edges from the reference image and from the sample image and respectively generating an edge reference image and an edge sample image; carrying out a dilation of the edges of the edge reference image and generating therefrom a dilated edge reference image; comparing the edge sample image with respect to the dilated edge reference image and generating an edge image of possible defects; and identifying the edges in the edge image of possible defects.

Abstract: Methods for diagnosing Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL) based on a diagnostic score, as well as determining MYC activity levels and selecting treatments based on a MYC activity score.

Abstract: The present invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating cancer (e.g., hematological malignancies in humans). A variety of biomarker chromosomal number alterations (CNAs) and biomarkers corresponding thereto, are provided, wherein alterations in the copy number of one or more of the biomarker CNAs and/or alterations in the amount, structure, and/or activity of one or more of the biomarkers comprised within the CNAs is associated with cancer status.