Abstract: A measuring device includes: a number n of sensors, a respective sensor of the number n of sensors being embodied to generate associated sensor data such that, overall, a number n of sensor data is generated by the number n of sensors; a learning unit embodied to calculate values of a number d of parameters of a hypothesis function on the basis of training data; a first measured quantity calculation unit to calculate a number m of first measured quantity values depending on the number n of sensor data on the basis of the hypothesis function and the calculated values of the number d of parameters of the hypothesis function; a second measured quantity calculation unit to calculate a number m? of second measured quantity values depending on the number n of sensor data on the basis of a model function; and a status unit which checks the calculation of the first measured quantity values on the basis of the second measured quantity values.

Abstract: Example apparatus are disclosed for a magazine for a self-loading firearm, the magazine comprising a magazine housing, and a magazine floor plate movably mounted to the magazine housing. The magazine floor plate is slidable between an open position and a closed position, wherein the magazine floor plate is pivotable relative to the magazine housing when in the open position.

Abstract: This invention provides an attenuated virus which comprises a modified viral genome containing nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce synonymous deoptimized codons into the genome. The instant attenuated virus may be used in a vaccine composition for inducing a protective immune response in a subject. The invention also provides a method of synthesizing the instant attenuated virus. Further, this invention further provides a method for preventing a subject from becoming afflicted with a virus-associated disease comprising administering to the subject a prophylactically effective dose of a vaccine composition comprising the instant attenuated virus.

Abstract: A system architecture of an autonomous vehicle, wherein the system architecture includes a plurality of application instances and nodes. The application instances are distributed and executed on the computation nodes according to a configuration, wherein measured sensor data of at least one sensor is input to at least part of the application instances, and wherein at least part of the application instances creates and provides control signals for controlling the vehicle. At least one context information of a prevailing context is gathered, and wherein the configuration is adapted according to the at least one gathered context information.

Abstract: A network node for coupling to a communication bus, the node comprising: a receiver configured to receive messages from the communication bus; and a transmitter configured to transmit first messages having a first message format and configured to transmit diagnosis messages having a second message format on the communication bus for use in determination of communication errors, wherein said transmitter is configured to send said one or more diagnosis messages having one or more of: (i) a predetermined pattern of symbols; (ii) a predetermined sending schedule; (iii) a predetermined line encoding method; (iv) a predetermined bit rate; (v) a predetermined position in one or more of the first messages; (vi) a predetermined signalling frequency that is out of a frequency band used for transmission of the first messages; and (vii) a predetermined signal strength different from the signal strength used to send the first messages.

Abstract: Example apparatus are disclosed for a magazine for a self-loading firearm, the magazine comprising a magazine housing, and a magazine floor plate movably mounted to the magazine housing. The magazine floor plate is slidable between an open position and a closed position, wherein the magazine floor plate is pivotable relative to the magazine housing when in the open position.

Abstract: A self-driving motor vehicle including numerous control units and numerous program codes for controlling the functions of the autonomous driving and other functions of the self-driving vehicle. Numerous program codes used for an autonomous driving mode are applied redundantly to at least two different control units. The self-driving motor vehicle may then be operated in an at least a partially autonomous driving mode. In this mode, the functions directly needed for satisfying a passenger's desire are determined, and weighted with regard to their importance in fulfilling the passenger's desires. At least one function of a lower order is then shut off, if the available resources in functioning control units and/or the power level in the self-driving motor vehicle are insufficient to execute program code for executing this function of the lower order.

Abstract: The present invention is the use of designed recombinant viruses for the treatment of various forms of malignant tumors. The recombinant viruses of the invention are those in which one or more regions of the wild type virus was exchanged with a synthetic recoded sequence that reduces the codon pair score relative to human codon pair bias, or that increase the number for CpG di-nucleotides, or that increases the number of UpA di-nucleotides. The method of the present invention is particularly useful for the treatment of malignant tumors in various organs, such as: breast, skin, colon, bronchial passage, epithelial lining of the gastrointestinal, upper respiratory and genito-urinary tracts, liver, prostate and the brain. Astounding remissions in experimental animals have been demonstrated for the treatment of malignant glioblastoma multiforme, as well as for the treatment of breast cancer and melanoma as well.

Abstract: The disclosure provides a method for operating an automatically driving vehicle, wherein application instances are executed over several computational nodes, wherein recognized faults are reacted to by switching to redundant application instances and then reconfiguring the configuration to restore specified redundancy conditions and/or segregation conditions, wherein the vehicle is transitioned to a safe state using at least one failover apparatus when at least one specified redundancy condition and/or at least one segregation condition cannot be met by the reconfiguration, and/or a specified time for reconfiguration is exceeded, and/or an unrecoverable malfunction has been recognized, wherein the at least one failover apparatus plans an emergency trajectory using a trajectory planner, wherein sensor data are detected via separate signal lines and supplied to the at least one failover apparatus, and wherein control signals are generated and transmitted via separate control lines to an actuator system of the v

Abstract: Reported herein are presumptively de-attenuating mutations that are useful, either individually or in combinations that may include other known mutations, in producing recombinant strains of human respiratory syncytial virus (RSV) exhibiting attenuation phenotypes. Also described herein is a novel RSV construct, Min_L-NPM2-1(N88K)L, which exhibits an attenuated phenotype, is stable and is as immunogenic as wild type RSV. The recombinant RSV strains described here are suitable for use as live-attenuated RSV vaccines. Exemplary vaccine candidates are described. Also provided are polynucleotide sequences capable of encoding the described viruses, as well as methods for producing and using the viruses.

Abstract: The invention relates to a method for the dynamic, context-based distribution of program codes in a control system of a vehicle. The control system has a plurality of control apparatuses for executing the program codes. The program codes are assigned to the corresponding control apparatuses of the control system by a global placement graph. In doing so, the global placement graph is calculated in a computing unit that is located outside of the control system. The data of the global placement graph are transmitted to the control system. It is provided for the global placement graph to be calculated based on the current configuration as well as known reconfigurations, wherein the selection of the next node of the global placement graph to be calculated is calculated using the probability of occurrence of an error as well as the effect of the error.

Abstract: Technologies and techniques for dynamic, context-based distribution of program codes in a control system in a vehicle. The control system includes numerous control units. The allocation of the program codes to the corresponding control units in the control system takes place using a global placement chart. The global placement chart is calculated on a computer, which may be located outside the control system. The data from the global placement chart are sent to the control system. Other aspects include an at least partially autonomous motor vehicle that has a control system for executing dynamic, context-based distribution of program codes.

Abstract: A microwave-based measuring device includes a number n of sensors, each sensor of the number n of sensors being embodied to generate associated sensor data such that, overall, a number n of items of sensor data are generated by way of the number n of sensors. A measurement variable calculation unit is embodied to calculate a number m of measurement variable values depending on the number n of items of sensor data on the basis of values of a number d of parameters. A learning unit is embodied to calculate the values of the number d of parameters on the basis of training data.

Abstract: The invention relates to a method for operating a self-propelled motor vehicle having a plurality of control units and a plurality of program codes for controlling the function of autonomous driving and possibly other functions of the self-propelled vehicle, wherein a plurality of program codes used for an autonomous driving mode are redundantly applied to at least two different control units. In doing so, the self-propelled motor vehicle is operated in an at least partially autonomous driving mode. In this mode, the functions directly needed to satisfy the passenger's wishes are ascertained and weighted corresponding to their relevance for satisfying the passenger's wishes. In so doing, the functions, or the scope of functions, are released depending on the achievement of a target achievement level.

Abstract: A radiometric measuring apparatus detects a measured variable in the form of a fill level, a point level, a density and/or a mass flow, and includes a scintillator embodied to generate light pulses upon excitation by ionizing radiation, an optoelectronic sensor embodied to convert the light pulses into a sensor signal, a first signal processing unit embodied to process the sensor signal into a first measured variable signal, an adjustable second signal processing unit embodied in a measurement setting to process the sensor signal into a second measured variable signal, wherein the second measured variable signal corresponds to the first measured variable signal in the case of a correctly processing first signal processing unit and a correctly processing second signal processing unit, and embodied in at least one operation setting to process the sensor signal into at least one operating variable signal, wherein the at least one operating variable signal does not correspond to the measured variable signals, a s

Abstract: A system and process for fabricating components from sheet material. Various embodiments of the disclosure combine punching of components from sheet material with a scoring process that outlines the components prior to the punching operation. In addition, a system and process where the scored portion of the sheet material that includes the scored outline is subjected to a high compression flattening process prior to the punching operation is disclosed. Performing the flattening operation prior to the punching operation has the effect of streamlining the process. That is, the sheet material can be easily handled and conveyed from the scoring process, through the flattening process, and to the punching process without need for separate handling of the component.

Abstract: A start-stop device and a corresponding method brings about an automatic switch-off and/or switch-on operation of an automatically switched-off drive machine of a motor vehicle, in particular of a motor vehicle having an automatic transmission. The start-stop device has a switch-off logic, by way of which an automatic switch-off of the drive machine can be brought about in the case of a moving vehicle in accordance with a predefined switch-off operating strategy, and a switch-on logic, by way of which an automatic switch-on of the automatically switched-off drive machine can be brought about in accordance with a predefined switch-on operating strategy. The switch-off operating strategy and/or the switch-on operating strategy are/is configured in a manner which is based on wheel torque.

Abstract: Embodiments of a device and method are disclosed. In an embodiment, an Ethernet communications device includes a physical layer (PHY) unit or a media access control (MAC) unit configured to perform media access control for the Ethernet communications device. The Ethernet communications device includes a security unit configured to manipulate a data stream in a data path within the Ethernet communications device when the data stream violates or conforms to a pre-defined policy.

Abstract: A measuring device includes: a number n of sensors, a respective sensor of the number n of sensors being embodied to generate associated sensor data such that, overall, a number n of sensor data is generated by the number n of sensors; a learning unit embodied to calculate values of a number d of parameters of a hypothesis function on the basis of training data; a first measured quantity calculation unit to calculate a number m of first measured quantity values depending on the number n of sensor data on the basis of the hypothesis function and the calculated values of the number d of parameters of the hypothesis function; a second measured quantity calculation unit to calculate a number m? of second measured quantity values depending on the number n of sensor data on the basis of a model function; and a status unit which checks the calculation of the first measured quantity values on the basis of the second measured quantity values.

Abstract: A microwave-based measuring device includes a number n of sensors, each sensor of the number n of sensors being embodied to generate associated sensor data such that, overall, a number n of items of sensor data are generated by way of the number n of sensors. A measurement variable calculation unit is embodied to calculate a number m of measurement variable values depending on the number n of items of sensor data on the basis of values of a number d of parameters. A learning unit is embodied to calculate the values of the number d of parameters on the basis of training data.