Patents by Inventor Steffen Wildum

Steffen Wildum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compound and method for the prevention of transmission of influenza virus
    Patent number: 11911394
    Abstract: The present invention relates to a method for preventing transmission of influenza, wherein said method comprises administering an effective amount of a compound to a patient having an influenza virus infection, herein referred to as “index patient”, wherein the compound has one of the formulae (I) and (II), or its pharmaceutically acceptable salt. The compound to be used in the present invention reduces infectivity of the influenza virus of the index patient, and therefore, reduces the risk of the index patient to trigger an influenza epidemic or an influenza pandemic as compared to a control patient.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: February 27, 2024
    Assignees: Shionogi & Co., Ltd.
    Inventors: Takeshi Noshi, Takahiro Noda, Ryu Yoshida, Takao Shishido, Kaoru Baba, Aeron C. Hurt, Leo Yi Yang Lee, Steffen Wildum, Klaus Kuhlbusch, Barry Clinch, Jan Michal Nebesky, Annabelle Lemenuel, Wendy S. Barclay, Jean-Eric Charoin, Yoshinori Ando
  • COMPOUND AND METHOD FOR THE PREVENTION OF TRANSMISSION OF INFLUENZA VIRUS
    Publication number: 20220331331
    Abstract: The present invention relates to a method for preventing transmission of influenza, wherein said method comprises administering an effective amount of a compound to a patient having an influenza virus infection, herein referred to as “index patient”, wherein the compound has one of the formulae (I) and (II), or its pharmaceutically acceptable salt. The compound to be used in the present invention reduces infectivity of the influenza virus of the index patient, and therefore, reduces the risk of the index patient to trigger an influenza epidemic or an influenza pandemic as compared to a control patient.
    Type: Application
    Filed: December 23, 2021
    Publication date: October 20, 2022
    Inventors: Takeshi NOSHI, Takahiro NODA, Ryu YOSHIDA, Takao SHISHIDO, Kaoru BABA, Aeron C. HURT, Leo Yi Yang LEE, Steffen WILDUM, Klaus KUHLBUSCH, Barry CLINCH, Jan Michal NEBESKY, Annabelle LEMENUEL, Wendy S. BARCLAY, Jean-Eric CHAROIN, Yoshinori ANDO
  • Compound and method for the prevention of transmission of influenza virus
    Patent number: 11389457
    Abstract: The present invention relates to a method for preventing transmission of influenza, wherein said method comprises administering an effective amount of a compound to a patient having an influenza virus infection, herein referred to as “index patient”, wherein the compound has one of the formulae (I) and (II), or its pharmaceutically acceptable salt. The compound to be used in the present invention reduces infectivity of the influenza virus of the index patient, and therefore, reduces the risk of the index patient to trigger an influenza epidemic or an influenza pandemic as compared to a control patient.
    Type: Grant
    Filed: March 26, 2020
    Date of Patent: July 19, 2022
    Assignees: Hoffmann-La Roche Inc., Shionogi & Co., Ltd.
    Inventors: Takeshi Noshi, Takahiro Noda, Ryu Yoshida, Takao Shishido, Kaoru Baba, Aeron C. Hurt, Leo Yi Yang Lee, Steffen Wildum, Klaus Kuhlbusch, Barry Clinch, Jan Michal Nebesky, Annabelle Lemenuel, Wendy S. Barclay, Jean-Eric Charoin, Yoshinori Ando
  • COMPOUND AND METHOD FOR THE PREVENTION OF TRANSMISSION OF INFLUENZA VIRUS
    Publication number: 20200330473
    Abstract: The present invention relates to a method for preventing transmission of influenza, wherein said method comprises administering an effective amount of a compound to a patient having an influenza virus infection, herein referred to as “index patient”, wherein the compound has one of the formulae (I) and (II), or its pharmaceutically acceptable salt. The compound to be used in the present invention reduces infectivity of the influenza virus of the index patient, and therefore, reduces the risk of the index patient to trigger an influenza epidemic or an influenza pandemic as compared to a control patient.
    Type: Application
    Filed: March 26, 2020
    Publication date: October 22, 2020
    Inventors: Takeshi NOSHI, Takahiro NODA, Ryu YOSHIDA, Takao SHISHIDO, Kaoru BABA, Aeron C. HURT, Leo Yi Yang LEE, Steffen WILDUM, Klaus KUHLBUSCH, Barry CLINCH, Michael J. NEBESKY, Annabelle LEMENUEL-DIOT, Wendy S. BARCLAY, Jean-Eric CHAROIN, Yoshinori ANDO
  • COMBINATION THERAPY OF AN HBV CAPSID ASSEMBLY INHIBITOR AND AN INTERFERON
    Publication number: 20200276198
    Abstract: The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBV capsid assembly inhibitor and an interferon for use in the treatment of hepatitis B virus infections.
    Type: Application
    Filed: March 20, 2020
    Publication date: September 3, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Lu Gao, Isabel Najera, Hong Shen, Fang Shen, Liping Shi, Steffen Wildum, Guang Yang
  • Combination therapy of an HBV capsid assembly inhibitor and an interferon
    Patent number: 10596173
    Abstract: The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBV capsid assembly inhibitor and an interferon for use in the treatment of hepatitis B virus infections.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: March 24, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Lu Gao, Isabel Najera, Hong Shen, Fang Shen, Liping Shi, Steffen Wildum, Guang Yang
  • COMBINATION THERAPY OF AN HBV CAPSID ASSEMBLY INHIBITOR AND A NUCLEOS(T)IDE ANALOGUE
    Publication number: 20190275052
    Abstract: The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBV capsid assembly inhibitor and a nucleoside or nucleotide analogue for use in the treatment or prophylaxis of chronic hepatitis B patient.
    Type: Application
    Filed: February 22, 2019
    Publication date: September 12, 2019
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Isabel Najera, Steffen Wildum
  • COMBINATION THERAPY OF AN HBV CAPSID ASSEMBLY INHIBITOR AND AN INTERFERON
    Publication number: 20180250301
    Abstract: The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBV capsid assembly inhibitor and an interferon for use in the treatment of hepatitis B virus infections.
    Type: Application
    Filed: May 3, 2018
    Publication date: September 6, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Lu Gao, Isabel Najera, Hong Shen, Fang Shen, Liping Shi, Steffen Wildum, Guang Yang
  • Carboxamide-substituted heteroaryl-pyrazoles and the use thereof
    Patent number: 9296720
    Abstract: This invention relates to new carboxamide-substituted heteroaryl-pyrazoles, method for their production, their use for the treatment and/or prophylaxis of diseases, as well as their use for the production of pharmaceutical agents for the treatment and/or prophylaxis of diseases, in particular retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: March 29, 2016
    Assignee: AICURIS GMBH & CO. KG
    Inventors: Steffen Wildum, Burkhard Klenke, Astrid Wendt
  • Tris(hetero)arylpyrazoles and use thereof
    Patent number: 9249148
    Abstract: The present invention relates to new tri(hetero)aryl pyrazoles, methods for their preparation, their use for treating and/or preventing diseases as well as their use in the preparation of drugs for treating and/or preventing diseases, in particular retroviral diseases in humans and/or animals.
    Type: Grant
    Filed: August 16, 2013
    Date of Patent: February 2, 2016
    Assignee: AICURIS GMBH & CO. KG
    Inventors: Steffen Wildum, Burkhard Klenke, Astrid Wendt
  • TRIS(HETERO)ARYLPYRAZOLES AND USE THEREOF
    Publication number: 20150203500
    Abstract: The present invention relates to new tri(hetero)aryl pyrazoles, methods for their preparation, their use for treating and/or preventing diseases as well as their use in the preparation of drugs for treating and/or preventing diseases, in particular retroviral diseases in humans and/or animals.
    Type: Application
    Filed: August 16, 2013
    Publication date: July 23, 2015
    Applicant: AICURIS GMBH & CO. KG
    Inventors: Steffen Wildum, Burkhard Klenke, Astrid Wendt
  • CARBOXAMIDE-SUBSTITUTED HETEROARYL-PYRAZOLES AND THE USE THEREOF
    Publication number: 20150105388
    Abstract: This invention relates to new carboxamide-substituted heteroaryl-pyrazoles, method for their production, their use for the treatment and/or prophylaxis of diseases, as well as their use for the production of pharmaceutical agents for the treatment and/or prophylaxis of diseases, in particular retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: November 29, 2012
    Publication date: April 16, 2015
    Applicant: AICURIS GMBH & CO. KG
    Inventors: Steffen Wildum, Burkhard Klenke, Astrid Wendt
  • Substituted (thiazolyl-carbonyl)imidazolidinones and use thereof
    Patent number: 8575357
    Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: November 5, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Kai Thede, Susanne Greschat, Kersten Matthias Gericke, Steffen Wildum, Daniela Paulsen
  • Substituted (thiophenyl-carbonyl)imidazolidinones, and use thereof
    Patent number: 8546438
    Abstract: The present invention relates to novel substituted (thiophenyl-carbonyl)imidazolidinones, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: October 1, 2013
    Inventors: Kai Thede, Susanne Greschat, Steffen Wildum, Daniela Paulsen
  • Substituted (pyrazolylcarbonyl)imidazolidinones and their use
    Patent number: 8399682
    Abstract: The present invention relates to novel substituted (pyrazolylcarbonyl)imidazolidinones, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: March 19, 2013
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Kai Thede, Susanne Greschat, Steffen Wildum, Daniela Paulsen
  • SUBSTITUTED (THIAZOLYL-CARBONYL)IMIDAZOLIDINONES AND USE THEREOF
    Publication number: 20130045999
    Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: February 17, 2012
    Publication date: February 21, 2013
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kai Thede, Susanne Greschat, Kersten Matthias Gericke, Steffen Wildum, Daniela Paulsen
  • Substituted furancarboxamides, and use thereof
    Patent number: 8324268
    Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: December 4, 2012
    Assignee: AiCuris GmbH & Co. KG
    Inventors: Kai Thede, Susanne Greschat, Steffen Wildum, Daniela Paulsen
  • SUBSTITUTED (THIOPHENYL-CARBONYL)IMIDAZOLIDINONES, AND USE THEREOF
    Publication number: 20120022123
    Abstract: The present invention relates to novel substituted (thiophenyl-carbonyl)imidazolidinones, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: June 16, 2011
    Publication date: January 26, 2012
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kai THEDE, Susanne GRESCHAT, Steffen WILDUM, Daniela PAULSEN
  • SUBSTITUTED FURANCARBOXAMIDES, AND USE THEREOF
    Publication number: 20120022059
    Abstract: The present invention relates to novel substituted furancarboxamides, methods for their production, their use for the treatment and/or prevention of diseases, as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: June 16, 2011
    Publication date: January 26, 2012
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kai THEDE, Susanne Greschat, Steffen Wildum, Daniela Paulsen
  • SUBSTITUTED (PYRAZOLYLCARBONYL)IMIDAZOLIDINONES AND THEIR USE
    Publication number: 20110124618
    Abstract: The present invention relates to novel substituted (pyrazolylcarbonyl)imidazolidinones, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals.
    Type: Application
    Filed: September 17, 2010
    Publication date: May 26, 2011
    Applicant: AiCuris GmbH & Co. KG
    Inventors: Kai THEDE, Susanne GRESCHAT, Steffen WILDUM, Daniela PAULSEN