Abstract: Systems, methods, and non-transitory computer-readable medium are provided that enable a component to be additively manufactured in a single build with multiple processing strategies. In one example aspect, a model representing a component is decomposed into submodels that each correspond to a subcomponent of the component. Each of the subcomponents can have a preselected metric associated therewith. The model can be decomposed into the submodels based at least in part on the preselected metrics. A set of build parameters is selected or assigned to each of the submodels based at least in part on the preselected metrics associated with the subcomponents. Overlap regions can be defined at each interface between adjacent subcomponents. The build parameters selected for adjacent subcomponents can be used to blend the build parameters for the defined overlap regions. The submodels and the blended build parameters can be used to additively manufacture the component.

Abstract: A shroud configured for installation on a component of a machine includes a shroud body including a plurality of arcuate sections hingedly coupled together, and a closure assembly including an engagement member and a receiving member. The plurality of arcuate sections include a first arcuate section hingedly coupled to one of the arcuate sections at a first edge and including the engagement member at an opposing second edge, and a second arcuate section hingedly coupled to one of the arcuate sections at a first edge and including the receiving member at an opposing second edge. The shroud body is configured to transition between an open configuration in which the engagement member and the receiving member are spaced apart from one another and a closed configuration in which the engagement member engages with the receiving member, the closure assembly maintaining the shroud body in the closed configuration.

Abstract: A shroud configured for installation on a component of a machine includes a shroud body including a plurality of arcuate sections hingedly coupled together, and a closure assembly including an engagement member and a receiving member. The plurality of arcuate sections include a first arcuate section hingedly coupled to one of the arcuate sections at a first edge and including the engagement member at an opposing second edge, and a second arcuate section hingedly coupled to one of the arcuate sections at a first edge and including the receiving member at an opposing second edge. The shroud body is configured to transition between an open configuration in which the engagement member and the receiving member are spaced apart from one another and a closed configuration in which the engagement member engages with the receiving member, the closure assembly maintaining the shroud body in the closed configuration.

Abstract: In certain embodiments, this present invention provides polypeptide compositions (e.g., antibodies and antigen binding portions thereof that bind to FcRn), and methods for modulating FcRn activity. In other embodiments, the present invention provides methods and compositions for treating autoimmune disorders.