Patents by Inventor Stelica Stelea
Stelica Stelea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11358140Abstract: An cartridge is combined with a smart device which is capable of communicating with a network to perform a portable, fast, field assay of a small sample biological analyte. A closed microfluidic circuit for mixes the analyte with a buffer with functionalized magnetic beads capable of being specifically combined with the analyte. A detector communicates with the microfluidic circuit in which the mixed analyte, buffer and combined functionalized magnetic beads are sensed. A microcontroller is coupled to detector for controlling the detector and for data processing an output assay signal from the detector. A user interface communicates with the microcontroller for providing user input and for providing user output through the smart device to the network.Type: GrantFiled: October 4, 2018Date of Patent: June 14, 2022Assignee: Autonomous Medical Devices Inc.Inventors: Josh Yehoshua Shachar, Sam Gurley, Aaron Cipriano, Peter Yin, Rob Purnell, Marc Rocklinger, Ming Petrullo, Stelica Stelea, Marlon S. Thomas
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Publication number: 20220097063Abstract: A field portable diagnostic apparatus uses a rotatable disk in which a microfluidic circuit is defined. The microfluidic circuit includes a centrifugal separation chamber receiving a sample to stratify the sample. A magnetic bead holding chamber is communicated to a mixing chamber, where mass amplifying functionalized magnetic-nanoparticles, held in a buffer solution and contained in the magnetic bead holding reservoir communicated to mixing chamber, are mixed with the separated fluid delivered to mixing chamber from the separation chamber. The functionalized magnetic nanoparticles conjugate with a target analyte in the sample. A magnet in proximity to a SAW chamber including a SAW detector draws the functionalized magnetic nanoparticles toward antibodies immobilized on the SAW sensor surface A wash reservoir is communicated to the SAW sensor chamber, and a cleanup/waste reservoir is communicated to the SAW chamber for receive fluid after it has passed through the SAW chamber.Type: ApplicationFiled: December 8, 2021Publication date: March 31, 2022Inventors: Josh Shachar, Sam Gurley, Aaron Cipriano, Peter Yin, Rob Purnell, Marc Rocklinger, Ming Petrullo, Stelica Stelea, Alexandra Perebikovsky
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Publication number: 20220097064Abstract: A field portable diagnostic apparatus uses a rotatable disk in which a microfluidic circuit is defined. The microfluidic circuit includes a centrifugal separation chamber receiving a sample to stratify the sample. A magnetic bead holding chamber is communicated to a mixing chamber, where mass amplifying functionalized magnetic-nanoparticles, held in a buffer solution and contained in the magnetic bead holding reservoir communicated to mixing chamber, are mixed with the separated fluid delivered to mixing chamber from the separation chamber. The functionalized magnetic nanoparticles conjugate with a target analyte in the sample. A magnet in proximity to a SAW chamber including a SAW detector draws the functionalized magnetic nanoparticles toward antibodies immobilized on the SAW sensor surface A wash reservoir is communicated to the SAW sensor chamber, and a cleanup/waste reservoir is communicated to the SAW chamber for receive fluid after it has passed through the SAW chamber.Type: ApplicationFiled: December 8, 2021Publication date: March 31, 2022Inventors: Josh Shachar, Sam Gurley, Aaron Cipriano, Peter Yin, Rob Purnell, Marc Rocklinger, Ming Petrullo, Stelica Stelea, Alexandra Perebikovsky
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Patent number: 11224874Abstract: A field portable diagnostic apparatus uses a rotatable disk in which a microfluidic circuit is defined. The microfluidic circuit includes a centrifugal separation chamber receiving a sample to stratify the sample. A magnetic bead holding chamber is communicated to a mixing chamber, where mass amplifying functionalized magnetic-nanoparticles, held in a buffer solution and contained in the magnetic bead holding reservoir communicated to mixing chamber, are mixed with the separated fluid delivered to mixing chamber from the separation chamber. The functionalized magnetic nanoparticles conjugate with a target analyte in the sample. A magnet in proximity to a SAW chamber including a SAW detector draws the functionalized magnetic nanoparticles toward antibodies immobilized on the SAW sensor surface A wash reservoir is communicated to the SAW sensor chamber, and a cleanup/waste reservoir is communicated to the SAW chamber for receive fluid after it has passed through the SAW chamber.Type: GrantFiled: February 25, 2019Date of Patent: January 18, 2022Assignee: Autonomous Medical Devices Inc.Inventors: Josh Yehoshua Shachar, Sam Gurley, Aaron Cipriano, Peter Yin, Rob Purnell, Marc Rocklinger, Ming Petrullo, Stelica Stelea
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Publication number: 20190201900Abstract: A field portable diagnostic apparatus uses a rotatable disk in which a microfluidic circuit is defined. The microfluidic circuit includes a centrifugal separation chamber receiving a sample to stratify the sample. A magnetic bead holding chamber is communicated to a mixing chamber, where mass amplifying functionalized magnetic-nanoparticles, held in a buffer solution and contained in the magnetic bead holding reservoir communicated to mixing chamber, are mixed with the separated fluid delivered to mixing chamber from the separation chamber. The functionalized magnetic nanoparticles conjugate with a target analyte in the sample. A magnet in proximity to a SAW chamber including a SAW detector draws the functionalized magnetic nanoparticles toward antibodies immobilized on the SAW sensor surface A wash reservoir is communicated to the SAW sensor chamber, and a cleanup/waste reservoir is communicated to the SAW chamber for receive fluid after it has passed through the SAW chamber.Type: ApplicationFiled: February 25, 2019Publication date: July 4, 2019Applicant: Sensor Kinesis Corp.Inventors: Josh Yehoshua Shachar, Sam Gurley, Aaron Cipriano, Peter Yin, Rob Purnell, Marc Rocklinger, Ming Petrullo, Stelica Stelea
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Publication number: 20190030533Abstract: An cartridge is combined with a smart device which is capable of communicating with a network to perform a portable, fast, field assay of a small sample biological analyte. A closed microfluidic circuit for mixes the analyte with a buffer with functionalized magnetic beads capable of being specifically combined with the analyte. A detector communicates with the microfluidic circuit in which the mixed analyte, buffer and combined functionalized magnetic beads are sensed. A microcontroller is coupled to detector for controlling the detector and for data processing an output assay signal from the detector. A user interface communicates with the microcontroller for providing user input and for providing user output through the smart device to the network.Type: ApplicationFiled: October 4, 2018Publication date: January 31, 2019Applicant: Sensor Kinesis Corp.Inventors: Yehoshua Shachar, Sam Gurley, Aaron Cipriano, Peter Yin, Rob Purnell, Marc Rocklinger, Ming Petrullo, Stelica Stelea, Marlon S. Thomas
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Publication number: 20170284390Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.Type: ApplicationFiled: April 18, 2017Publication date: October 5, 2017Inventors: Wayne A. Noda, Stelica Stelea
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Publication number: 20170216089Abstract: An externally-applied heat exchange pad has three layers laminated together, an inner and outer non-conductive layer and a middle conductive layer. A leak in the inner layer causes coolant to contact the middle layer and change impedance, which can be sensed and used as an indication of an impending total leak of the pad.Type: ApplicationFiled: April 11, 2017Publication date: August 3, 2017Inventors: Stelica Stelea, David Searl Kimball, Lynn Miyeko Shimada, Kenneth A. Collins
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Patent number: 9624926Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.Type: GrantFiled: October 24, 2012Date of Patent: April 18, 2017Assignee: Zoll Circulation, Inc.Inventors: Wayne A. Noda, Stelica Stelea
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Patent number: 9615966Abstract: An externally-applied heat exchange pad has three layers laminated together, an inner and outer non-conductive layer and a middle conductive layer. A leak in the inner layer causes coolant to contact the middle layer and change impedance, which can be sensed and used as an indication of an impending total leak of the pad.Type: GrantFiled: October 17, 2012Date of Patent: April 11, 2017Assignee: ZOLL CIRCULATION, INC.Inventors: Stelica Stelea, David Searl Kimball, Lynn Miyeko Shimada, Kenneth A. Collins, Grant Palmer
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Patent number: 8790304Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.Type: GrantFiled: September 4, 2012Date of Patent: July 29, 2014Assignee: Zoll Circulation, Inc.Inventors: Wayne A. Noda, Stelica Stelea
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Publication number: 20140151017Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.Type: ApplicationFiled: February 7, 2014Publication date: June 5, 2014Applicant: Zoll Circulation, Inc.Inventors: Wayne Noda, Stelica Stelea
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Patent number: 8696723Abstract: An externally-applied heat exchange pad has three layers laminated together, an inner and outer non-conductive layer and a middle conductive layer. A leak in the inner layer causes coolant to contact the middle layer and change impedance, which can be sensed and used as an indication of an impending total leak of the pad.Type: GrantFiled: February 20, 2013Date of Patent: April 15, 2014Assignee: Zoll Circulation, Inc.Inventors: Stelica Stelea, David Searl Kimball, Lynn Miyeko Shimada, Kenneth A. Collins, Grant Palmer
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Patent number: 8690826Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.Type: GrantFiled: November 1, 2012Date of Patent: April 8, 2014Assignee: Zoll Circulation, Inc.Inventors: Wayne A. Noda, Stelica Stelea
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Publication number: 20140067027Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.Type: ApplicationFiled: November 4, 2013Publication date: March 6, 2014Applicant: Zoll Circulation, Inc.Inventors: Wayne Noda, Stelica Stelea
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Publication number: 20130325090Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.Type: ApplicationFiled: August 7, 2013Publication date: December 5, 2013Applicant: Zoll Circulation Inc.Inventors: Wayne Noda, Stelica Stelea
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Patent number: 8388577Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.Type: GrantFiled: June 20, 2007Date of Patent: March 5, 2013Assignee: Zoll Circulation, Inc.Inventors: Wayne Noda, Stelica Stelea
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Publication number: 20120325426Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.Type: ApplicationFiled: September 4, 2012Publication date: December 27, 2012Applicant: Zoll Circulation Inc.Inventors: Wayne A. Noda, Stelica Stelea
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Patent number: 8317491Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.Type: GrantFiled: June 20, 2007Date of Patent: November 27, 2012Assignee: Zoll Circulation, Inc.Inventors: Wayne Noda, Stelica Stelea
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Patent number: 8308788Abstract: An externally-applied heat exchange pad has three layers laminated together, an inner and outer non-conductive layer and a middle conductive layer. A leak in the inner layer causes coolant to contact the middle layer and change impedance, which can be sensed and used as an indication of an impending total leak of the pad.Type: GrantFiled: October 27, 2011Date of Patent: November 13, 2012Assignee: Zoll Circulation, Inc.Inventors: Stelica Stelea, David Searl Kimball, Lynn Miyeko Shimada, Kenneth A. Collins, Grant Palmer