Patents by Inventor Stelios C. Tsinontides

Stelios C. Tsinontides has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for formulation of carbapenem antibiotic compositions
    Patent number: 6548492
    Abstract: A novel process for preparing a stabilized, lyophilized carbapenem, antibiotic formulation suitable for intravenous administration to patients in need thereof, wherein the active ingredient is of formula II: The process entails compounding a unstable, monosodium salt carbapenem with a sodium bicarbonate solution at a temperature range of from about 0° to about 5° C. while maintaining a pH between about 7.0 and about 8.0, filtering the resultant solution, bottling under sterile conditions, and lyophilizing to produce the formulation.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: April 15, 2003
    Assignee: Merck & Co., Inc.
    Inventors: Anthony Al-Dehneh, William A. Hunke, Kathleen J. Illig, Anand Kanike, Hiren Patel, Scott D. Reynolds, Stelios C. Tsinontides
  • Process for formulation of antibiotic compounds
    Patent number: 6486150
    Abstract: The present invention involves a process for preparing a stable final formulation product of a compound of formula I, or its pharmaceutically acceptable salt, hydrate or solvate by incorporating a suitable carbon dioxide source to an unstable monosodium adduct of carbapenem antibiotic compound.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: November 26, 2002
    Assignee: Merck & Co., Inc.
    Inventors: William A. Hunke, Kathleen J. Illig, Anand Kanike, Scott D. Reynolds, Stelios C. Tsinontides, Anthony S. Al-Dehneh, Hiren S. Patel
  • Process for formulation of antibiotic compounds
    Publication number: 20020002160
    Abstract: The present invention involves a process for preparing a stable final formulation product of a compound of formula I, 1
    Type: Application
    Filed: April 27, 2001
    Publication date: January 3, 2002
    Inventors: William A. Hunke, Kathleen J. Illig, Anand Kanike, Scott D. Reynolds, Stelios C. Tsinontides, Anthony S. Al-Dehneh, Hiren S. Patel