Patents by Inventor Stella Tommassi

Stella Tommassi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DIRECTING DNA METHYLATION IN MAMMALIAN CELLS USING HOMOLOGOUS, SHORT DOUBLE STRANDED RNAS
    Publication number: 20070231907
    Abstract: The invention provides methods for methylating a gene of interest in a cell. The methods include exposing a mammalian cell to an siRNA molecule which is specific for a gene of interest in the cell. The methods also include introducing into the cell DNA sequences encoding a sense strand and an antisense strand of an siRNA which is specific for the gene of interest. The siRNA directs methylation of the gene of interest.
    Type: Application
    Filed: May 29, 2007
    Publication date: October 4, 2007
    Applicant: CITY OF HOPE
    Inventors: John ROSSI, Daniela CASTANOTTO, Gerd PFEIFFER, Stella TOMMASSI
  • Methods for directing DNA methylation in mammalian cells using homologous short double stranded RNAs
    Publication number: 20040171118
    Abstract: The invention provides methods for methylating a gene of interest in a cell. The methods include exposing a mammalian cell to an siRNA molecule which is specific for a gene of interest in the cell. The methods also include introducing into the cell DNA sequences encoding a sense strand and an antisense strand of an siRNA which is specific for the gene of interest. The siRNA directs methylation of the gene of interest.
    Type: Application
    Filed: February 12, 2004
    Publication date: September 2, 2004
    Applicant: City of Hope
    Inventors: John J. Rossi, Daniela Castanotto, Gerd Pfeiffer, Stella Tommassi