Patents by Inventor Stepan HAVEL

Stepan HAVEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted aminothiazoles as inhibitors of nucleases
    Patent number: 11584742
    Abstract: Compounds represented by the structural formula (1) R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: February 21, 2023
    Assignee: MASARYKOVA UNIVERZITA
    Inventors: Kamil Paruch, Benoit Carbain, Stepan Havel, Jiri Damborsky, Jan Brezovsky, Lukas Daniel, Alexandra Sisakova, Fedor Nikulenkov, Lumir Krejci
  • Substituted propanamides as inhibitors of nucleases
    Patent number: 11453663
    Abstract: Compounds represented by the structural formula (1) where R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: September 27, 2022
    Assignee: MASARYKOVA UNIVERZITA
    Inventors: Kamil Paruch, Benoit Carbain, Stepan Havel, Vit Vsiansky, Fedor Nikulenkov, Lumir Krejci
  • SUBSTITUTED PROPANAMIDES AS INHIBITORS OF NUCLEASES
    Publication number: 20220073507
    Abstract: Compounds represented by the structural formula (1) where R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
    Type: Application
    Filed: April 15, 2019
    Publication date: March 10, 2022
    Applicant: MASARYKOVA UNIVERZITA
    Inventors: Kamil PARUCH, Benoit CARBAIN, Stepan HAVEL, Vit VSIANSKY, Fedor NIKULENKOV, Lumir KREJCI
  • SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF NUCLEASES
    Publication number: 20220002282
    Abstract: Compounds represented by the structural formula (1) R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
    Type: Application
    Filed: April 15, 2019
    Publication date: January 6, 2022
    Applicant: MASARYKOVA UNIVERZITA
    Inventors: Kamil PARUCH, Benoit CARBAIN, Stepan HAVEL, Jiri DAMBORSKY, Jan BREZOVSKY, Lukas DANIEL, Alexandra SISAKOVA, Fedor NIKULENKOV, Lumir KREJCI
  • Pyrazolotriazines as inhibitors of nucleases
    Patent number: 9969741
    Abstract: The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3 and R4 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: May 15, 2018
    Assignee: MASARYKOVA UNIVERZITA
    Inventors: Jiri Damborsky, Fedor Nikulenkov, Alexandra Sisakova, Stepan Havel, Lumir Krejci, Benoit Carbain, Jan Brezovsky, Lukas Daniel, Kamil Paruch
  • PYRAZOLOTRIAZINES AS INHIBITORS OF NUCLEASES
    Publication number: 20170197966
    Abstract: The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3 and R4 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
    Type: Application
    Filed: June 17, 2015
    Publication date: July 13, 2017
    Applicant: MASARYKOVA UNIVERZITA
    Inventors: JIRI DAMBORSKY, Fedor NIKULENKOV, Alexandra SISAKOVA, Stepan HAVEL, Lumir KREJCI, Benoit CARBAIN, Jan BREZOVSKY, Lukas DANIEL, Kamil PARUCH