Patents by Inventor Stephan Bartel

Stephan Bartel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dicarboxylic acid derivatives and their use
    Patent number: 8609727
    Abstract: The present application relates to novel dicarboxylic acid derivatives, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Grant
    Filed: October 17, 2006
    Date of Patent: December 17, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Eva-Maria Becker, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Andreas Knorr, Dieter Lang
  • Tetrazole derivatives and their use for the treatment of cardiovascular diseases
    Patent number: 8183271
    Abstract: The present application relates to novel tetrazole derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Grant
    Filed: October 9, 2006
    Date of Patent: May 22, 2012
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Eva-Maria Becker, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Andreas Knorr
  • Difluorophenol derivatives and their use
    Patent number: 8173704
    Abstract: The present application relates to novel difluorophenol derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Grant
    Filed: October 9, 2006
    Date of Patent: May 8, 2012
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Eva-Maria Becker, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Andreas Knorr
  • Biphenyl compounds useful in the treatment or prevention of cardiovascular disorders
    Patent number: 7998988
    Abstract: The invention relates to biphenyl compounds of formula (I): wherein U, V and W together form a group of the formula *—CH?CH—CH<, *—CH2—CH2—CH< or *—CH2—CH2—N<, in which * means the point of linkage to the phenyl ring; A is O or CH2; and D, E, X, Y, Z, R1, R2, o, n, and p are as defined in the specification. The invention also relates to pharmaceutical compositions of the compound of the compounds. The compounds and pharmaceutical compositions of the invention can be used in the treatment or prevention of cardiovascular disorders.
    Type: Grant
    Filed: October 9, 2006
    Date of Patent: August 16, 2011
    Assignee: Bayer Schering Pharma Aktiengellschaft
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Klaus Münter, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder
  • Dicarboxylic Acid Derivatives and their Use
    Publication number: 20100029772
    Abstract: The present application relates to novel dicarboxylic acid derivatives, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: October 17, 2006
    Publication date: February 4, 2010
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Eva-Maria Becker, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Andreas Knorr, Dieter Lang
  • Difluorophenol Derivatives and Their Use
    Publication number: 20090291993
    Abstract: The present application relates to novel difluorophenol derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: October 9, 2006
    Publication date: November 26, 2009
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Eva-Maria Becker, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Andreas Knorr
  • Heterocyclic compounds with carboxyl isostere groups and their use for the treatment of cardiovascular diseases
    Publication number: 20090227640
    Abstract: The present application relates to novel heterocyclic compounds, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: October 9, 2006
    Publication date: September 10, 2009
    Applicant: BAYER HEALTHCARE AG
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Klaus Münter, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder
  • Tetrazole Derivatives and Their Use for the Treatment of Cardiovascular Diseases
    Publication number: 20090215843
    Abstract: The present application relates to novel tetrazole derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: October 9, 2006
    Publication date: August 27, 2009
    Inventors: Stephan Bartel, Michael Hahn, Wahed Ahmed Moradi, Eva-Maria Becker, Thomas Rölle, Johannes-Peter Stasch, Karl-Heinz Schlemmer, Frank Wunder, Andreas Knorr
  • Novel Pyrimidine Derivatives and their Use
    Publication number: 20080261990
    Abstract: The present invention relates to novel pyrimidine derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of cardiovascular diseases, in particular dyslipidemias, arteriosclerosis, coronary heart disease, thrombosis and metabolic syndrome.
    Type: Application
    Filed: September 10, 2005
    Publication date: October 23, 2008
    Applicant: Bayer healthCare AG
    Inventors: Elke Dittrich-Wengenroth, Lars Barfacker, Axel Kretschmer, Claudia Hirth-Dietrich, Peter Ellinghaus, Martin Raabe, Hilmar Bischoff, Christian Pilger, Ulrich Rosentreter, Stephan Bartel, Klemens Lustig, Armin Kern, Dieter Lang, Marcus Bauser
  • USE OF 7-(2-OXA-5,8-DIAZABICYLCO[4.3.0]NON-8-YL)-QUINOLONE CARBOXYLIC ACID AND NAPHTHYRIDON CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF HELIOBACTER PYLORI INFECTIONS AND ASSOCIATED GASTRODUODENAL DISEASES
    Patent number: 6432948
    Abstract: The invention relates to the use of quinolone- and naphthyridonecarboxylic acid derivatives, which are substituted in the 7-position by a 2-oxa-5,8-diazabicyclo[4.3.0]-non-8-yl) radical, and their pharmaceutically utilizable hydrates and/or salts for the therapy of Helicobacter pylori infections and the gastroduodenal disorders associated therewith.
    Type: Grant
    Filed: November 8, 1999
    Date of Patent: August 13, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Matzke, Uwe Petersen, Thomas Jaetsch, Stephan Bartel, Thomas Schénke, Thomas Himmler, Bernd Baasner, Hans-Otto Werling, Klaus Schaller, Harald Labischinski
  • Medicaments for viral diseases
    Publication number: 20020082264
    Abstract: Chromanone derivatives are highly active antiviral agents. Combinations of chromanones and/or chromanols with HBV polymerase inhibitors, HBV DNA inhibitors or HBV core protein inhibitors and/or isoxazoles and, where appropriate, interferon inhibit the replication of HBV viruses better than agents disclosed previously.
    Type: Application
    Filed: August 30, 2001
    Publication date: June 27, 2002
    Inventors: Susanne Nikolic, Stephan Bartel, Michael Brands, Ulrich Niewohner, Arnold Paessens, Erwin Graef, Karl-Heinz Schlemmer, Kerstin Henninger, Rainer Endermann, Olaf Weber, Diana Koletzki
  • Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolonecarboxylic acid and -naphthyridonecarboxylic acid derivatives for the therapy of Helicobacter pylori infections and associated gastroduodenal disorders
    Publication number: 20010036941
    Abstract: The invention relates to the use of quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in position 7 by a 1-aninomethyl-2-oxa-7-azabicyclo[3.3.0]oct-7-yl radical, and of their salts for the therapy of Helicobacter pylori infections and associated gastroduodenal disorders.
    Type: Application
    Filed: April 10, 2001
    Publication date: November 1, 2001
    Inventors: Uwe Petersen, Michael Matzke, Thomas Jaetsch, Thomas Schenke, Thomas Himmler, Stephan Bartel, Bernd Baasner, Hans-Otto Werling, Klaus Schaller, Harald Labischinski, Rainer Endermann
  • Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolone carboxylic acid and naphthyridone carboxylic acid derivatives for treating Helicobacter pylori infections and the gastroduodenal diseases associated therewith
    Patent number: 6288081
    Abstract: The invention relates to the use of quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in position 7 by a 1-aminomethyl-2-oxa-7-azabicyclo[3.3.0]oct-7-yl radical, and of their salts for the therapy of Helicobacter pylori infections and associated gastroduodenal disorders.
    Type: Grant
    Filed: August 6, 1999
    Date of Patent: September 11, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Michael Matzke, Thomas Jaetsch, Thomas Schenke, Thomas Himmler, Stephan Bartel, Bernd Baasner, Hans-Otto Werling, Klaus Schaller, Harald Labischinski, Rainer Endermann
  • Use of 7-(2-oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-quinolone carboxylic acid and naphthyridon carboxylic acid derivatives for the treatment of Helicobacter pylori infections and associated gastroduodenal diseases
    Patent number: 6133260
    Abstract: The invention relates to the use of quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a 2-oxa-5,8-diazabicyclo[4.3.0]-non-8-yl) radical, and their pharmaceutically utilizable hydrates and/or salts for the therapy of Helicobacter pylori infections and the gastroduodenal disorders associated therewith.
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: October 17, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Matzke, Uwe Petersen, Thomas Jaetsch, Stephan Bartel, Thomas Schenke, Thomas Himmler, Bernd Baasner, Hans-Otto Werling, Klaus Schaller, Harald Labischinski
  • Heteroatom-containing benzocyclopentane-oxazolidinones
    Patent number: 6069160
    Abstract: The invention relates to heteroatom-containing benzocyclopentaneoxazolidinones, to processes for their preparation and their use as medicaments, especially as antibacterial medicaments.
    Type: Grant
    Filed: April 12, 1996
    Date of Patent: May 30, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Andreas Stolle, Dieter Habich, Stephan Bartel, Bernd Riedl, Martin Ruppelt, Hanno Wild, Rainer Endermann, Klaus-Dieter Bremm, Hein-Peter Kroll, Harald Labischinski, Klaus Schaller, Hans-Otto Werling
  • 7-isoindolinyl-quinolone derivatives and 7-isoindolinyl-naphthyridone derivatives
    Patent number: 6018054
    Abstract: The invention relates to intermediate compounds for preparing novel quinolone derivatives- and naphthyridone derivatives which are substituted in the 7-position by a partially hydrogenated isoindolinyl ring, to processes for their preparation and to antibacterial agents and feed additives containing them.
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: January 25, 2000
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Philipps, Stephan Bartel, Andreas Krebs, Uwe Petersen, Thomas Schenke, Klaus-Dieter Bremm, Rainer Endermann, Karl Georg Metzger, Burkhard Mielke
  • Quinolone- and naphthyridonecarboxylic acid derivatives
    Patent number: 5990122
    Abstract: The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a tricyclic amine radical, their salts, processes for their preparation and antibacterial compositions comprising these compounds.
    Type: Grant
    Filed: January 7, 1998
    Date of Patent: November 23, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Thomas Schenke, Thomas Jaetsch, Stephan Bartel, Klaus Dieter Bremm, Rainer Endermann, Karl Georg Metzger
  • Quinolone- and naphthyridonecarboxylic acid derivatives
    Patent number: 5986105
    Abstract: The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a tricyclic amine radical, their salts, processes for their preparation and antibacterial compositions comprising these compounds.
    Type: Grant
    Filed: November 20, 1998
    Date of Patent: November 16, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Thomas Schenke, Thomas Jaetsch, Stephan Bartel, Klaus Dieter Bremm, Rainer Endermann, Karl Georg Metzger
  • Heteroaryl-oxazolidinones
    Patent number: 5922708
    Abstract: The invention relates to novel heteroaryl-oxazolidinones of the general formula (I): ##STR1## in which the substituents are as defined in the description, to processes for their preparation and to their use as drugs, especially as antibacterial drugs.
    Type: Grant
    Filed: February 3, 1997
    Date of Patent: July 13, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bernd Riedl, Dieter Habich, Andreas Stolle, Martin Ruppelt, Stephan Bartel, Walter Guarnieri, Rainer Endermann, Hein-Peter Kroll
  • 2-oxo- and 2-thio-1,2-dihydroquinolinyl-oxazolidinones
    Patent number: 5861413
    Abstract: The present invention relates to 2-oxo- and 2-thio-1,2-dihydroquinolinyl-oxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.
    Type: Grant
    Filed: January 9, 1997
    Date of Patent: January 19, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventors: Dieter Habich, Andreas Stolle, Bernd Riedl, Martin Ruppelt, Stephan Bartel, Walter Guarnieri, Rainer Endermann, Hein-Peter Kroll