Abstract: The present invention relates to compounds of formula (I) as well as pharmaceutically acceptable salts thereof. The are useful as HSL inhibitors and may, for example, be used in treatment of diabetes, metabolic syndrome, dyslipidemia, atherosclerosis, and obesity.

Abstract: The present invention relates to compounds of formula (I) as well as pharmaceutically acceptable salts thereof. The are useful as HSL inhibitors and may, for example, be used in treatment of diabetes, metabolic syndrome, dyslipidemia, atherosclerosis, and obesity.

Abstract: A diaphragm assembly for the diaphragm pump of an inhaling apparatus compressor contains a flexible diaphragm 1,21 with a first opening 2, 22, a lower diaphragm disc 6, 26, with a second opening 8, 28, and an upper diaphragm disc 14, 38 with a third opening 16, 40, said diaphragm discs 6, 14, 26, 38 having a smaller diameter than the flexible diaphragm 1, 21, and a securement member 18, 44, for clamping the diaphragms 1, 21, between the lower diaphragm discs 6, 26 and the upper diaphragm discs 14, 38, said securement member 18, 44 being guided through the first, second and third opening 2, 12, 16, 22, 28, 40 and being in engagement with a diaphragm drive device.

Abstract: The present invention relates to a liquid atomizer device for producing aerosols. The device includes a first housing part (A) which includes an inner member (3) of an atomizer nozzle and a first connection for connecting the first housing part (A) to a further housing part to form a nebulizing chamber (1), and further includes a second housing part (B) that includes an outer member of the atomizer nozzle which can be brought into engagement with the inner member (3) to form the atomizer nozzle, and a second connection means (11) that can be brought into engagement with the first connection (9) for connecting the second housing part to the first housing part. The invention is characterized in that a service life indicator (L) is arranged at a place that does not impede the flow passing through the device, but is accessible to the aerosol and a sterilant.

Abstract: The invention is directed to a portable inhalation device. This device is compact and portable and contains a compressor, an air filter and a power supply, and permits, together with an aerosol nebuliser, the mobile administration of drugs by inhalation.

Abstract: Inhalation therapy is not only used for the treatment of respiratory tract diseases, but also increasingly for administering other medicinal substances. In this kind of therapy, the substance is made available to the patient for inhalation in the form of a liquid vapor having very small droplet diameters (ca. 1 to 5 um) and is transported together with the inhaled air into the respiratory tracts. The inventive atomizer consists of a cylindrical atomizing space with two openings for respectively supplying and withdrawing the liquid vapor, the openings being arranged in such a manner that a spiral vortex is formed which extends about the longitidunal axis of the atomizing space.

Abstract: The invention relates to a transportable inhalation device, which can be driven with an accumulator (25), independently of the electric network. In an aerosol mister (7) that is separated from the rest of the device, a medication solution is atomized by means of compressed-air, introduced to an aerosol. The compressed-air that is required for this is generated by a compressed-air generator 23. A hand-actuated valve (14), mounted on the aerosol mister (7), blocks the supply of compressed-air. The compressed air generator (23) is driven by an electric motor (24). The electric motor (23) is controlled by means of an electronic controller (31), to which a pressure sensor (30), which is arranged between the compressed-air generator (23) and the valve (14) is attached electrically. In response to this pressure sensor (30), the controller (31) automatically switches on the electric motor (24), as soon as a pre-determined minimum pressure is exceeded within the compressed-air hose (11).

Abstract: The invention relates to an inhaler for atomization, dispersing and mixing of fluid or powdery substances by means of a pressurized gas flow (30) for production of an aerosol. The inhaler consists of an atomization head (1) arranged in the upper end of a two part hand grip (2). The atomization head (1) has a central atomization nozzle comprised of a nozzle head (23) and a gas flow controller (27), a connection passage (21) for pressurized gas supply, an air supply chimney (28) and an aerosol outlet passage (28) for connection to a mouthpiece. The nozzle head (23) contains a central pressurized gas passage (22) and lateral suction channels (24,25) for the atomization material (26). According to the invention the atomization head (1) has a spherical shape and is surrounded by correspondingly shaped hollow spherical parts (5,6) of the hand grip.