Patents by Inventor Stephan D. Glenn

Stephan D. Glenn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11844768
    Abstract: Nordihydroguaiaretic acid (NDGA) derivatives, including terameprocol (TMP) have utility as anti-viral agents for use on patients infected with or at risk of infection with a coronavirus, including SARS-CoV-2. In vitro studies show coronavirus-infected cells treated with 0.2 ?M-20 ?M TMP show reduced viral RNA activity in vitro. Treatment-related cytotoxicity is not shown at 0.2 ?M TMP with a low percentage of cytotoxicity shown at 5 ?M TMP. In application, the NDGA derivatives may be administered to a patient intravenously at a molar concentration of 0.1-50 ?M or orally at a molar concentration of 0.1-100 ?M.
    Type: Grant
    Filed: January 14, 2022
    Date of Patent: December 19, 2023
    Assignee: Erimos Pharmaceuticals, LLC
    Inventors: Jeffrey Khoo, Stephan D. Glenn
  • Publication number: 20220233466
    Abstract: Nordihydroguaiaretic acid (NDGA) derivatives, including terameprocol (TMP) have utility as anti-viral agents for use on patients infected with or at risk of infection with a coronavirus, including SARS-CoV-2. In vitro studies show coronavirus-infected cells treated with 0.2 ?M-20 ?M TMP show reduced viral RNA activity in vitro. Treatment-related cytotoxicity is not shown at 0.2 ?M TMP with a low percentage of cytotoxicity shown at 5 ?M TMP. In application, the NDGA derivatives may be administered to a patient intravenously at a molar concentration of 0.1-50 ?M or orally at a molar concentration of 0.1-100 ?M.
    Type: Application
    Filed: January 14, 2022
    Publication date: July 28, 2022
    Inventors: Jeffrey Khoo, Stephan D. Glenn
  • Patent number: 9750933
    Abstract: A non-invasive, transcutaneous electrical device stimulates nerves using unpulsed, constant direct current. The device uses a constant, unpulsed direct electric current of low constant voltage and power through air core uninsulated wire coil electrodes. The device includes a switch to open or close the circuit, a fuse that serves as the automatic overload trip voltage level, and two wire coil electrodes of uninsulated wire. The coil electrodes are positioned on the forehead directly superior to the eyes proximal to the supraorbital and supratrochlear nerves and apply a direct current transcutaneously to the forehead.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: September 5, 2017
    Inventors: Daniel T. Gregory, Roy A. Stimits, Stephan D. Glenn
  • Patent number: 9603875
    Abstract: A method of making a consumable product containing purified embryonated Trichuris suis ova (TSO) preferably includes steps of: storing the TSO in an acidic solution; adding a food preservative to the acidic solution to produce a preservative-acid-solution; forming a mixing solution by raising the pH of the preservative-acidic-solution to match the pH of a food substance by titrating the preservative-acidic-solution with an acid neutralizer so that the pH changes at a rate of not more than 1 pH unit per 24 hours, preferably to a pH not higher than 5.0; and producing the consumable product by combining the mixing solution and the food substance while maintaining the temperature of the consumable product between 1 degree Centigrade and 47 degrees Centigrade.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: March 28, 2017
    Assignee: NeuOva, LLC
    Inventors: Stephan D. Glenn, Daniel T. Gregory, Jr., Roy A. Stimits, Frank Detlev Goj
  • Publication number: 20160175585
    Abstract: A non-invasive, transcutaneous electrical device stimulates nerves using unpulsed, constant direct current. The device uses a constant, unpulsed direct electric current of low constant voltage and power through air core uninsulated wire coil electrodes. The device includes a switch to open or close the circuit, a fuse that serves as the automatic overload trip voltage level, and two wire coil electrodes of uninsulated wire. The coil electrodes are positioned on the forehead directly superior to the eyes proximal to the supraorbital and supratrochlear nerves and apply a direct current transcutaneously to the forehead.
    Type: Application
    Filed: December 18, 2015
    Publication date: June 23, 2016
    Inventors: Daniel T. Gregory, Roy A. Stimits, Stephan D. Glenn
  • Patent number: 6565827
    Abstract: Methods for the treatment of lymphoma by administration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy.
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: May 20, 2003
    Assignees: Coulter Pharmaceutical, Inc., The Regents of the University of Michigan
    Inventors: Mark S. Kaminski, Gregory M. Butchko, Stephan D. Glenn, Richard L. Wahl
  • Patent number: 6287537
    Abstract: Methods for the treatment of lymphoma by adminstration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: September 11, 2001
    Assignees: The Regents of the University of Michigan, Coulter Pharmaceutical, Inc.
    Inventors: Mark S. Kaminski, Gregory M. Butchko, Stephan D. Glenn, Richard L. Wahl
  • Patent number: 6090365
    Abstract: Methods for the treatment of lymphoma by administration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy.
    Type: Grant
    Filed: November 18, 1997
    Date of Patent: July 18, 2000
    Assignees: Coulter Pharmaceutical, Inc., Regents of the University of Michigan
    Inventors: Mark S. Kaminski, Gregory M. Butchko, Stephan D. Glenn, Richard L. Wahl
  • Patent number: 6015542
    Abstract: Methods for the treatment of lymphoma by administration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy also described is a composition useful in the treatment of lymphoma.
    Type: Grant
    Filed: September 10, 1996
    Date of Patent: January 18, 2000
    Assignees: Coulter Pharmaceutical, Inc., The Regents of the University of Michigan
    Inventors: Mark S. Kaminski, Gregory M. Butchko, Stephan D. Glenn, Richard L. Wahl
  • Patent number: 5843398
    Abstract: Methods for the treatment of lymphoma by administration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy.
    Type: Grant
    Filed: April 26, 1996
    Date of Patent: December 1, 1998
    Assignees: Coulter Pharmaceutical, Inc., Regents of the University of Michigan
    Inventors: Mark S. Kaminski, Gregory M. Butchko, Stephan D. Glenn, Richard L. Wahl
  • Patent number: 5595721
    Abstract: Methods for the treatment of lymphoma by adminstration of a B cell-specific antibody are described. The invention encompasses providing to a patient both unlabeled antibodies and antibodies labeled with a radioisotope. A principal advantage of the method is that tumor responses can be obtained in a radiometric dose range that does not require hematopoietic stem cell replacement as an adjunct therapy.
    Type: Grant
    Filed: September 16, 1993
    Date of Patent: January 21, 1997
    Assignee: Coulter Pharmaceutical, Inc.
    Inventors: Mark S. Kaminski, Gregory M. Butchko, Stephan D. Glenn, Richard L. Wahl
  • Patent number: 5221483
    Abstract: A single filtration device containing coated filter membranes and absolute pore filters is provided in which the membranes and absolute pore filters are present in two sections of the filter device. The filter device will remove up to about 98% of the endotoxins in addition to removing viruses with an efficiency of at least 4.6.times.10.sup.5 and DNA to less than 10 picograms per 500 mg sample.
    Type: Grant
    Filed: November 4, 1991
    Date of Patent: June 22, 1993
    Assignee: Coulter Corporation
    Inventors: Stephan D. Glenn, Gregory Butchko, Edward O'Connell, Paulette Smariga
  • Patent number: 5076933
    Abstract: A single filtration device containing coated filter membranes and absolute pore filters is provided in which the membranes and absolute pore filters are present in two sections of the filter device. The filter device will remove viruses, as modeled by type-C Xenotropic retrovirus, with an efficiency of at least 4.6.times.10.sup.5 ; remove DNA from levels of 10 .mu.g/sample to levels below 10 picograms per 500 mg sample of monoclonal antibody; and will remove at least 97% of some bacterial endotoxins.
    Type: Grant
    Filed: June 29, 1990
    Date of Patent: December 31, 1991
    Assignee: Coulter Corporation
    Inventors: Stephan D. Glenn, Edward O'Connell, Paulette Smariga, Gregory Butchko