Patents by Inventor Stephan HOLZSCHUH

Stephan HOLZSCHUH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Formulation of contrast media and process of preparation thereof
    Patent number: 11944690
    Abstract: The present disclosure relates to a liquid pharmaceutical formulation comprising a DOSA-derived tetra-chelate of formula (I), in which M is an ion of a paramagnetic metal, preferably a Gd3+ ion, and R1, R2, R3, R4 and R5 are as defined in the claims, in a pharmaceutical acceptable solvent. The present disclosure also relates to a method of preparation of said liquid pharmaceutical formulation and to a method of imaging involving said liquid pharmaceutical formulation.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: April 2, 2024
    Assignee: BAYER AKTIENGESELLSCHAFT
    Inventors: Stephan Holzschuh, Thomas Frenzel, Gregor Jost, Jessica Lohrke, Wolfgang Ebert, Thomas Brumby, Wolfgang Halfbrodt
  • FORMULATION OF CONTRAST MEDIA AND PROCESS OF PREPARATION THEREOF
    Publication number: 20220008562
    Abstract: The present disclosure relates to a liquid pharmaceutical formulation comprising a DOSA-derived tetra-chelate of formula (I), in which M is an ion of a paramagnetic metal, preferably a Gd3+ ion, and R1, R2, R3, R4 and R5 are as defined in the claims, in a pharmaceutical acceptable solvent. The present disclosure also relates to a method of preparation of said liquid pharmaceutical formulation and to a method of imaging involving said liquid pharmaceutical formulation.
    Type: Application
    Filed: November 21, 2019
    Publication date: January 13, 2022
    Inventors: Stephan HOLZSCHUH, Thomas FRENZEL, Gregor JOST, Jessica LOHRKE, Wolfgang EBERT, Thomas BRUMBY, Wolfgang HALFBRODT