Patents by Inventor Stephan Ladisch

Stephan Ladisch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gangliosides with immunosuppressive activity
    Patent number: 6326361
    Abstract: A method for suppressing immune responses in animals by administering gangliosides to the animal. Gangliosides having terminal sialic acid groups are disclosed as being especially effective as immunosuppressive agents. The especially effective immunosuppressive gangliosides include GM4 and GM5. Ganglioside compositions for use in suppressing immune responses are also disclosed.
    Type: Grant
    Filed: June 2, 1993
    Date of Patent: December 4, 2001
    Assignee: The Regents of the University of California
    Inventor: Stephan Ladisch
  • Synthetic ganglioside derivatives
    Patent number: 5567684
    Abstract: Synthetic compounds which are useful for suppressing an immune response are disclosed. The synthetic compounds have the formula ##STR1## wherein A is a carbohydrate moiety which corresponds to the carbohydrate moiety of a naturally occurring ganglioside, n is 5 to 20 and m is to 20. Also presented are methods for suppressing an immune response in an animal and compositions of matter employing the compounds as shown above.
    Type: Grant
    Filed: September 14, 1994
    Date of Patent: October 22, 1996
    Assignee: The Regents of The University of California
    Inventors: Stephan Ladisch, Akira Hasegawa
  • Gangliosides with immunosuppressive ceramide moieties
    Patent number: 5366963
    Abstract: A method for suppressing immune responses in animals by administering a mixture of gangliosides to the animal where the gangliosides have heterogeneous ceramide structures containing fatty acid portions with carbon chain lengths of 21-30 or less than 18 carbon atoms. Ganglioside mixtures which are homogeneous with respect to the fatty acid portion are also effective immunosuppressive agents when the carbon chain length of the fatty acid portion is less than 18. Compositions containing the above specified ganglioside mixtures are also disclosed.
    Type: Grant
    Filed: February 23, 1993
    Date of Patent: November 22, 1994
    Assignee: The Regents of the University of California
    Inventor: Stephan Ladisch
  • Avoidance of the immunosuppressive and antiproliferative effects of lipid emulsions
    Patent number: 4551449
    Abstract: Lipid emulsions for human therapy containing cholesterol or other sterols in an amount effective to substantially mitigate immunosuppressive and antiproliferative effects.The use of these novel lipid emulsions in subjects receiving hyperalimentation therapy.
    Type: Grant
    Filed: November 16, 1983
    Date of Patent: November 5, 1985
    Assignee: The Regents of the University of California
    Inventor: Stephan Ladisch