Abstract: The invention relates a method and an apparatus of predicting or planning a temperature distribution (52) in a body. The method comprises the steps of: a) obtaining a model of the body (50) related to a temperature transport mechanism or temperature distribution (52) in the body; b) simulating an application of heat to at least a part of the body such as targeted tissue; c) determining and/or predicting the temperature (52) or heat distribution in at least a part of the body using the model of the body (50).

Abstract: The invention relates to a computer-implemented medical data processing method for determining a heartbeat signal describing the heartbeat of a patient in the time domain, the method comprising executing, on a processor of a computer, steps of: a) acquiring, at the processor, acceleration measurement data describing an acceleration in the time domain of an anatomical body part measured on an external surface of the anatomical body part; b) determining, by the processor, component analysis data describing a result of an independent component analysis in the time domain of the acceleration measurement data; c) acquiring, at the processor, heartbeat template data describing template shapes of heartbeat in the time domain; d) determining, by the processor and based on the component analysis data and the heartbeat template data, recurrent shape data describing a recurrence of certain signal shapes in the component analysis data; e) determining, based on the recurrent shape data, heartbeat signal data describing a

Abstract: The present invention relates to a data processing method of determining a trajectory of a medical instrument to be inserted into a patient's body for treatment of a target region in the patient's body, the method being executed by a computer and comprising the following steps: a) acquiring medical image data comprising medical image information describing an image of an anatomical body part; b) acquiring target region extent data comprising target region extent information describing a spatial extent of the target region in the medical image information; c) determining, based on the target region extent data, whether the spatial extent of the target region in the medical image information comprises more than one image particle; d) if it is determined that the target region comprises more than a predetermined number of image particles, determining, based on the medical image data, image particle weight data comprising image particle weight information describing a weight describing a tissue type component

Abstract: The invention relates a method and an apparatus of predicting or planning a temperature distribution (52) in a body. The method comprises the steps of: a) obtaining a model of the body (50) related to a temperature transport mechanism or temperature distribution (52) in the body; b) simulating an application of heat to at least a part of the body such as targeted tissue; c) determining and/or predicting the temperature (52) or heat distribution in at least a part of the body using the model of the body (50).

Abstract: The invention relates to a computer-implemented medical data processing method for determining a heartbeat signal describing the heartbeat of a patient in the time domain, the method comprising executing, on a processor of a computer, steps of: a) acquiring, at the processor, acceleration measurement data describing an acceleration in the time domain of an anatomical body part measured on an external surface of the anatomical body part; b) determining, by the processor, component analysis data describing a result of an independent component analysis in the time domain of the acceleration measurement data; c) acquiring, at the processor, heartbeat template data describing template shapes of heartbeat in the time domain; d) determining, by the processor and based on the component analysis data and the heartbeat template data, recurrent shape data describing a recurrence of certain signal shapes in the component analysis data; e) determining, based on the recurrent shape data, heartbeat signal data describing a

Abstract: An agent delivery catheter including a first hollow tube and a second hollow tube that protrudes from a distal opening of the first hollow tube and defines an agent delivery lumen extending along the entire length of the catheter. The distal end of the first tube is coupled to the second tube to form an annular cavity between the first tube and the second tube, the annular cavity provided for accommodating a retractable stylet shaft. An adapting member is disposed on and coupled to a proximal end of a ceramic member and for receiving a distal end of the stylet shaft.

Abstract: The invention relates to an agent delivery catheter, comprising a first hollow tube and a second hollow tube 2 which protrudes from a distal opening of the first hollow tube 1 and defines an agent delivery lumen 3 extending along the entire length of the catheter, wherein: the distal end of the first tube 1 is coupled to the second tube 2 to form an annular cavity 4 between the first tube 1 and the second tube 2, the annular cavity 4 being configured to accommodate a retractable stylet shaft 5; a ceramic member 6 which is disposed at the distal end of the first tube 1, in particular distally with respect to the distal opening of the first tube 1, encompasses the second tube 2 and couples the first tube 1 to the second tube 2, in particular via a third hollow tube 23 which encompasses the first tube 1 and the ceramic member 6; and a protective shrink-fit tube 7 is disposed radially on the outside of the ceramic member 6 and extends over at least the length of the ceramic member 6.

Abstract: A method for planning an infusion of a medical substance into a target region acquires non-patient-specific anatomical data from an atlas in the form of target region geometry information describing target and off-target regions for which an infusion of the medical substance is intended and regions to be avoided, respectively. Target coverage information is derived describing a minimum dose of the medical substance to be infused into the target region and describing a maximum dose of the medical substance to be applied to the off-target region. Relationship information describes a relationship between a physical parameter of an infusion setup and a selected spatial distribution of the medical substance. Infusion setup information for the infusion is determined that describes a planned infusion setup and is based on the relationship information and information related to the target and off-target regions.

Abstract: The present invention relates to a data processing method for determining an infusion location in an anatomical region of interest of a patient's body for infusing a medical substance, the method being executed by a computer and comprising steps of: a) acquiring permeability data comprising information about the permeability of anatomical vessels in the body; b) acquiring body vessels set data comprising information about a body vessel set, wherein the body vessel set represents a set of at least one anatomical body vessel in the patient's body and wherein the body vessel set data comprises information about the spatial structure of the at least one body vessel; c) acquiring coverage condition data comprising information about a predetermined coverage of a target region with the medical substance; d) determining, for a plurality of candidate infusion locations, candidate coverage data comprising information about a candidate coverage of a target region with the medical substance based on the permeability data

Abstract: The present invention relates to a data processing method for providing variation data which describe a physically-varying anatomical structure, in particular an indiscernible anatomical structure, in particular a non-enhancing tumor, comprising the steps of: providing second image data which describe a second image of a region of an anatomical body, wherein the region includes a second anatomical part which includes the physically-varying anatomical structure; providing first image data which represent a first image of the same region, wherein said same region includes a first anatomical part which does not include the physically-varying anatomical structure or which includes the physically-varying anatomical structure in a different physical state than in the second anatomical part; providing position change data which describe positional changes of corresponding image elements between the first image and the second image, on the basis of the first and second image data; and providing the variation data on

Abstract: The present invention relates to a data processing method of determining a trajectory of a medical instrument to be inserted into a patient's body for treatment of a target region in the patient's body, the method being executed by a computer and comprising the following steps: a) acquiring medical image data comprising medical image information describing an image of an anatomical body part; b) acquiring target region extent data comprising target region extent information describing a spatial extent of the target region in the medical image information; c) determining, based on the target region extent data, whether the spatial extent of the target region in the medical image information comprises more than one image particle; d) if it is determined that the target region comprises more than a predetermined number of image particles, determining, based on the medical image data, image particle weight data comprising image particle weight information describing a weight describing a tissue type component

Abstract: A method for planning an infusion of a medical liquid by an infusion apparatus comprising an infusion device, wherein the method comprises the steps of: acquiring planning scan data which represent a medical image of at least a body region (3) of a patient and are obtained by a planning scan before the infusion device is positioned; determining a planned device position from the planning scan data; acquiring verification scan data which represent a medical image of the region of the patient after the infusion device has been positioned; determining a source volume of the liquid from the verification scan data; and determining infusion parameters from the verification scan data and the source volume.

Abstract: The present invention refers to a data processing method for planning an infusion of a medical substance into a target region in an anatomical body part, wherein the medical substance is to be infused by means of an infusion setup which comprises an infusion device for performing the infusion as well as the medical substance, the method comprising: a) acquiring relationship data comprising relationship information which describes a relationship between at least one physical parameter of the infusion setup and a predetermined spatial distribution of the medical substance; b) acquiring target coverage data comprising target coverage information describing a planned coverage of the target region by the medical substance; c) determining infusion setup data comprising infusion setup information which describes a planned infusion setup, based on the relationship data and the target coverage data.

Abstract: The present invention relates to a data processing method for providing variation data which describe a physically-varying anatomical structure, in particular an indiscernible anatomical structure, in particular a non-enhancing tumour, comprising the steps of: providing second image data which describe a second image of a region of an anatomical body, wherein the region includes a second anatomical part which includes the physically-varying anatomical structure; providing first image data which represent a first image of the same region, wherein said same region includes a first anatomical part which does not include the physically-varying anatomical structure or which includes the physically-varying anatomical structure in a different physical state than in the second anatomical part; providing position change data which describe positional changes of corresponding image elements between the first image and the second image, on the basis of the first and second image data; and providing the variation data on

Abstract: A catheter for administering a substance into a patient's tissue including a number of pressure sensors for detecting changes in the shape of the catheter or s a backflow along the surface of the catheter. In response to the pressure distribution profile collected along the surface or length of the catheter, the physician may simulate or adapt the substance administration plan to accommodate the actual position of the catheter or the backflow along the surface of the catheter.

Abstract: The present invention relates to a data processing method for determining an infusion location in an anatomical region of interest of a patient's body for infusing a medical substance, the method being executed by a computer and comprising steps of: a) acquiring permeability data comprising information about the permeability of anatomical vessels in the body; b) acquiring body vessels set data comprising information about a body vessel set, wherein the body vessel set represents a set of at least one anatomical body vessel in the patient's body and wherein the body vessel set data comprises information about the spatial structure of the at least one body vessel; c) acquiring coverage condition data comprising information about a predetermined coverage of a target region with the medical substance; d) determining, for a plurality of candidate infusion locations, candidate coverage data comprising information about a candidate coverage of a target region with the medical substance based on the permeability data

Abstract: A method for enabling the planning of a treatment of a tumour within a body using a therapeutic virus, wherein the virus distribution in the body is calculated by simulating the virus replication process, starting from an initial virus distribution, and the calculated virus distribution is provided for the planning.

Abstract: A method for planning an infusion of a medical liquid by an infusion apparatus comprising an infusion device, wherein the method comprises the steps of: acquiring planning scan data which represent a medical image of at least a body region (3) of a patient and are obtained by a planning scan before the infusion device is positioned; determining a planned device position from the planning scan data; acquiring verification scan data which represent a medical image of the region of the patient after the infusion device has been positioned; determining a source volume of the liquid from the verification scan data; and determining infusion parameters from the verification scan data and the source volume.

Abstract: The invention relates a method and an apparatus of predicting or planning a temperature distribution (52) in a body. The method comprises the steps of : a) obtaining a model of the body (50) related to a temperature transport mechanism or temperature distribution (52) in the body; b) simulating an application of heat to at least a part of the body such as targeted tissue; c) determining and/or predicting the temperature (52) or heat distribution in at least a part of the body using the model of the body (50).

Abstract: The invention relates to a catheter stylet for stiffening a catheter during the placing process, wherein the stylet comprises an accommodating lumen for at least one fluid-guiding line of the catheter. It also relates to a catheter stylet catheter system, comprising such a stylet and comprising a catheter which comprises a fluid-guiding line, and to a method for stiffening a catheter during the placing process, wherein a stylet which comprises an accommodating lumen is arranged around at least one fluid-guiding line of the catheter.