Abstract: A method and apparatus is provided for determining a stroke volume (SV) of an individual, comprising the steps of: providing a first pulse contour stroke volume based on one or more characteristics of a measured arterial blood pressure waveform or providing a conventionally derived pulse contour stroke volume, determining at least one perfusion parameter descriptive for the perfusion through the fat free mass and the adipose mass of a body of the individual, and/or determining at least one fluid responsiveness parameter function depending on a fluid responsiveness parameter descriptive for a heart-lung interaction of the individual, and adjusting the first pulse contour stroke volume or the conventionally derived pulse contour stroke volume based on at the least one of the perfusion parameter and/or the fluid responsiveness parameter function to provide a second pulse contour stroke volume.

Abstract: Blood pressure measuring device with a flexible pressure collar, to surround a body part at least partially, with a pressure sensor element, wherein the shape of the pressure collar can be adapted to the outer contour of the body part, the pressure collar being at least partially inelastic. Further, the flexible pressure collar for a blood pressure measuring device to the relates pressure collar being inelastic and the shape being adapted to the outer contour of a body part. A method for non-invasive blood pressure measurement on a patient's body part with a blood pressure measuring device includes: positioning the pressure collar on the body part; setting the pressure collar such that it exerts pressure in the pulsatile region of the patient on the body part; and recording the pulsation for the period of at least one breathing cycle of the patient in the form of pulsation signals.

Abstract: Determining the transition between systole and diastole is important for pulse contour-analytical determination of hemodynamic, first of all cardiac output. During the temporal progression of arterial pressure P(t) on which pulse contour analysis is based, the transition between systole and diastole appears as a local minimum. This local slump of the pressure curve downward is very short and is often little recognizable in the actually measured curves due to inaccuracies conditioned by measuring techniques. It was also found that the transition between systole and diastole can be more reliably and accurately determined as the site of maximum curvature of function P(t). Consequently, the invention relates to a device having a calculation unit that comprises evaluation means for detecting the site of maximum curvature of function P(t) in a detection area between the maximum and minimum functional value of the pulse cycle as the site of transition between systole and diastole.

Abstract: An arterially measured pressure signal is continuously read in and temporarily stored in the working memory (RAM). The function p(t) is processed by the central processing unit (CPU), to calculate the heart/time volume PCCO and other hemodynamic parameters. The calculation comprises the following steps: The systemic vascular resistance SVRk is calculated for the current pulse period. The stroke volume SVk is numerically determined from the pressure values of a pulse period, according to the following equation: SV k ? ? ( p i ? ( t ) SVR k + C k ? ( p i ) ? ? p i ? t ) with the compliance C(p)=(MAP?CVP)k/[SVR·<dp/dt>k]·ƒ(p). The difference between the mean arterial pressure MAP and the central venous pressure CVP, and the mean incline of the pressure curve in the diastole <dp/dt>, are re-determined for the current pulse period. The heart/time volume calculated in the current pulse period results from PCCOk=SVk·HR.

Abstract: Determining the transition between systole and diastole is important for pulse contour-analytical determination of hemodynamic, first of all cardiac output. During the temporal progression of arterial pressure P(t) on which pulse contour analysis is based, the transition between systole and diastole appears as a local minimum. This local slump of the pressure curve downward is very short and is often little recognizable in the actually measured curves due to inaccuracies conditioned by measuring techniques. It was also found that the transition between systole and diastole can be more reliably and accurately determined as the site of maximum curvature of function P(t). Consequently, the invention relates to a device having a calculation unit that comprises evaluation means for detecting the site of maximum curvature of function P(t) in a detection area between the maximum and minimum functional value of the pulse cycle as the site of transition between systole and diastole.

Abstract: An arterially measured pressure signal is continuously read in and temporarily stored in the working memory (RAM). The function p(t) is processed by the central processing unit (CPU), to calculate the heart/time volume PCCO and other hemodynamic parameters. The calculation comprises the following steps: The systemic vascular resistance SVRk is calculated for the current pulse period. The stroke volume SVk is numerically determined from the pressure values of a pulse period, according to the following equation: SV k ? ? ( p i ? ( t ) SVR k + C k ? ( p i ) ? ? p i ? t ) with the compliance C(p)=(MAP?CVP)k/[SVR·<dp/dt>k]·f(p). The difference between the mean arterial pressure MAP and the central venous pressure CVP, and the mean incline of the pressure curve in the diastole <dp/dt>, are re-determined for the current pulse period. The heart/time volume calculated in the current pulse period results from PCCOk=SVk·HR.