Abstract: dsRNAi oligonucleotides can be used in methods for the treatment of NASH, preferably the advanced fibrotic and/or cirrhotic stages thereof, using dosage regimens comprising a loading phase followed by a maintenance phase.

Abstract: Some embodiments include a system. The system comprises an input device, an output device, one or more processing modules, and one or more non-transitory memory storage modules storing computer instructions. The non-transitory memory storage module(s) are configured to run on the processing module(s) and perform acts of: receiving a search query; and responsive to receiving the search query: identifying a restricted group of questions, the questions of the restricted group of questions being relevant to the search query; transforming the restricted group of questions into a first group of questions and a second group of questions, the questions of the restricted group of questions comprising the questions of the first group of questions and the questions of the second group of questions; and communicating to a user the first group of questions and the second group of questions. Other embodiments of related systems and methods are also provided.

Abstract: A computer-implemented method analyzes resources in a network. An analyzer executing on one or more computing devices receives an input having one or more identifiers to one or more target resources in the network. The analyzer also receives one or more values for one or more performance metrics relevant to the one or more target resources. The analyzer automatically uses pre-stored performance metrics to prepare one or more rankings of performance for the one or more target resources and one or more field resources based on the one or more performance metrics. The analyzer automatically uses the prepared one or more rankings to identify, from one or more target resources, one or more identified target resources having a performance potential higher than remaining target resources of the one or more target resources, a corresponding system, computing device, and non-transitory computer-readable storage medium.

Abstract: Some embodiments include a system. The system can include an input device, an output device, one or more processors, and one or more non-transitory memory storage devices storing computer instructions configured to run on the one or more processors and perform acts including: receiving a primary user search query; constructing a graphical visualization having multiple nodes and one or more edge connectors connecting one or more primary node pairs of the multiple nodes; and presenting the graphical visualization at an electronic display. The multiple nodes can include a first node associated with the primary user search query and one or more second nodes associated with one or more primary filtered search queries of multiple leading search queries related to the primary user search query. Other embodiments of related systems and methods are also provided.

Abstract: Some embodiments include a system. The system comprises an input device, an output device, one or more processing modules, and one or more non-transitory memory storage modules storing computer instructions. The non-transitory memory storage module(s) are configured to run on the processing module(s) and perform acts of: receiving a search query; and responsive to receiving the search query: identifying a restricted group of questions, the questions of the restricted group of questions being relevant to the search query; transforming the restricted group of questions into a first group of questions and a second group of questions, the questions of the restricted group of questions comprising the questions of the first group of questions and the questions of the second group of questions; and communicating to a user the first group of questions and the second group of questions. Other embodiments of related systems and methods are also provided.

Abstract: A laundry drum for a laundry treatment machine that is rotatable about an axis, wherein the laundry drum includes a drum jacket made of metal sheet, and wherein the drum jacket has throughflow holes and linear elevations that are distributed in a peripheral direction and that extend transversely to a periphery line. The linear elevations rise at a distance from one another in a straight or curved line from cylindrical regions of the laundry drum. Agitators are disposed on an inner periphery of the drum jacket and the throughflow holes are disposed in the cylindrical regions.

Abstract: A method for washing laundry in a program-controlled domestic laundry-care appliance including the steps of heating washing liquid present in the tub and heating the washing liquid to a specific washing temperature set as a function of determined parameter values that are specific to the laundry being washed and/or the appliance.

Abstract: A drum for a laundry treatment machine that is rotatably mounted within the housing of the laundry treatment machine, and wherein the drum includes a bottom disk and a jacket which are individually or jointly provided with a curved structure. The curved structure includes at least two rows of prism-type embossings that have substantially rectangular base, and the at least two rows encompass at least partially the drum. A surface of embossings that is directed in a circumferential direction of the drum is arranged at a steep angle to the jacket; an opposing surface of the embossings is arranged at a flat angle to the jacket; and lateral surfaces of the embossings are arranged at least nearly at a right angle to the jacket.

Abstract: A laundry drum for a laundry treating machine, wherein the laundry drum includes a drum cover that has a cylindrical shape and structures that are distributed in a circumferential direction of the drum cover. The structures project from the cylindrical shape of the drum cover that is mounted in the laundry drum. Further, the structures are formed from inwardly bulging linear elevations that extend along a circumferential line.

Abstract: A laundry drum for a laundry treatment machine mounted within a housing for rotation about a non-vertical axis, the laundry drum including a drum casing having a plurality of stamped recesses formed therein in a manner such that at least one sectional plane of the laundry drum lying at right angles to the axis of rotation has an at least approximately circular shape, the laundry drum including a drum casing having the curved stamped recesses formed therein in a manner wherein in the alignment of a surface contour lying in the drum casing is formed a surface having a plurality of arcuate edges which merge continuously into one another with a single axis of symmetry extending at least approximately in the circumferential direction of the drum casing.

Abstract: A laundry drum for a laundry treatment machine mounted within a housing for rotation about a non-vertical axis, the laundry drum including a drum casing having a plurality of stamped recesses formed therein in a manner such that at least one sectional plane of the laundry drum lying at right angles to the axis of rotation has an at least approximately circular shape, the laundry drum including a drum casing having the curved stamped recesses formed therein in a manner wherein in the alignment of a surface contour lying in the drum casing is formed a surface having a plurality of arcuate edges which merge continuously into one another with a single axis of symmetry extending at least approximately in the circumferential direction of the drum casing.

Abstract: A drum for a laundry treatment machine that is rotatably mounted within the housing of the laundry treatement machine, and wherein the drum includes a bottom disk and a jacket which are individually or jointly provided with a curved structure. The curved structure includes at least two rows of prism-type embossings that have substantially rectangular base, and the at least two rows encompass at least partially the drum. A surface of embossings that is directed in a circumferential direction of the drum is arranged at a steep angle to the jacket; an opposing surface of the embossings is arranged at a flat angle to the jacket; and lateral surfaces of the embossings are arranged at least nearly at a right angle to the jacket.

Abstract: A laundry drum for a laundry treatment machine that is rotatable about an axis, wherein the laundry drum includes a drum jacket made of metal sheet, and wherein the drum jacket has throughflow holes and linear elevations that are distributed in a peripheral direction and that extend transversely to a periphery line. The linear elevations rise at a distance from one another in a straight or curved line from cylindrical regions of the laundry drum. Agitators are disposed on an inner periphery of the drum jacket and the throughflow holes are disposed in the cylindrical regions.

Abstract: A laundry drum for a laundry treating machine, wherein the laundry drum includes a drum cover that has a cylindrical shape and structures that are distributed in a circumferential direction of the drum cover. The structures project from the cylindrical shape of the drum cover that is mounted in the laundry drum. Further, the structures are formed from inwardly bulging linear elevations that extend along a circumferential line.

Abstract: A method is provided for washing laundry in a program-controlled domestic appliance for doing laundry. Washing liquid present in the tub is heated and the washing liquid is heated to a specific washing temperature set as a function of determined parameter values that are specific to the laundry and/or of the appliance.

Abstract: The invention relates to a water-circulating household appliance that may be, for example a washing machine, washer-drier, or clothes drier. The household appliance includes a rotatably mounted washing drum with a drum casing and a drum cover face. The washing drum is embossed with protrusions in the form of embossments whose edges are ellipsoidal.

Abstract: A cylinder washing machine includes a front-loading cylinder, the shell of which is provided with holes and is surrounded by a container. The cylinder washing machine includes a cycle for spin-drying the laundry contained in the cylinder. To prevent water that has already been spun out of the laundry from being transported back to the interior space of the cylinder during spin-drying, precautions are taken to prevent substantially any air from flowing from the container through the interior space of the cylinder and back to the container during spin-drying.

Abstract: A cylinder washing machine includes a front-loading cylinder, the shell of which is provided with holes and is surrounded by a container. The cylinder washing machine includes a cycle for spin-drying the laundry contained in the cylinder. To prevent water that has already been spun out of the laundry from being transported back to the interior space of the cylinder during spin-drying, precautions are taken to prevent substantially any air from flowing from the container through the interior space of the cylinder and back to the container during spin-drying.