Patents by Inventor Stephan Walters

Stephan Walters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8241485
    Abstract: The present invention is based on the discovery of NAD+ and NADP+ mediator compounds that do not bind irreversibly to thiol groups in the active sites of intracellular dehydrogenase enzymes. Such mediator compounds avoid a common mode of enzyme inhibition. The mediators can therefore increase the stability and reliability of the electrical response in amperometric electrodes constructed from NAD- or NADP-dependent enzymes.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: August 14, 2012
    Assignee: Abbott Laboratories
    Inventors: Nigel J. Forrow, Gurdial S. Sanghera, Jared L. Watkin, Stephan Walters
  • Patent number: 8221612
    Abstract: The present invention is based on the discovery of NAD+ and NADP+ mediator compounds that do not bind irreversibly to thiol groups in the active sites of intracellular dehydrogenase enzymes. Such mediator compounds avoid a common mode of enzyme inhibition. The mediators can therefore increase the stability and reliability of the electrical response in amperometric electrodes constructed from NAD- or NADP-dependent enzymes.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: July 17, 2012
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Nigel J. Forrow, Gurdial S. Sanghera, Jared L. Watkin, Stephan Walters
  • Patent number: 7998337
    Abstract: The present invention is based on the discovery of NAD+ and NADP+ mediator compounds that do not bind irreversibly to thiol groups in the active sites of intracellular dehydrogenase enzymes. Such mediator compounds avoid a common mode of enzyme inhibition. The mediators can therefore increase the stability and reliability of the electrical response in amperometric electrodes constructed from NAD- or NADP-dependent enzymes.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: August 16, 2011
    Assignee: Abbott Laboratories
    Inventors: Nigel J. Forrow, Gurdial S. Sanghera, Jared L. Watkin, Stephan Walters
  • Publication number: 20090090625
    Abstract: The present invention is based on the discovery of NAD+ and NADP+ mediator compounds that do not bind irreversibly to thiol groups in the active sites of intracellular dehydrogenase enzymes. Such mediator compounds avoid a common mode of enzyme inhibition. The mediators can therefore increase the stability and reliability of the electrical response in amperometric electrodes constructed from NAD- or NADP-dependent enzymes.
    Type: Application
    Filed: September 30, 2008
    Publication date: April 9, 2009
    Inventors: Nigel J. Forrow, Gurdial S. Sanghera, Jared L. Watkin, Stephan Walters