Abstract: The present invention provides a compound having the structure of Formula (I) or a pharmaceutically acceptable salt, hydrate, solvate, or isomer thereof, for the controlled delivery and release of Agent.

Abstract: In an embodiment there is: negative voltage generator configured to generate an output having a negative voltage from an input having a positive voltage comprising an input node configured to receive an alternating signal, an output node for outputting an output voltage of the generator and a ground node, a switching element configured to provide a conductive and non-conductive flow path between a first terminal and a second terminal in response to a control signal; a control element adapted to control the flow of current therethrough between a first terminal and a second terminal.

Abstract: A method for operating a cutting dredger in open water, in particular to control a ground reaction force during dredging operations, the dredger including; a floating body, an elongate cutter ladder having a cutting head at its lowerable free end for dredging, which cutter ladder is hingeably coupled to the floating body and hingeable between an upwards position and a cutting position wherein the cutting head engages matter to be cut away at the floor of a body of water.

Abstract: An amplifier arrangement for amplifying an alternating signal, comprising an amplifier and an adaptive biasing circuit, the amplifier configured to receive an alternating signal for amplification and a bias signal for biasing the amplifier from the adaptive biasing circuit, the adaptive biasing circuit comprising a PTAT circuit wherein the PTAT circuit is configured to receive the alternating signal and modulate the bias signal based on the alternating signal.

Abstract: In an embodiment there is: A negative voltage generator configured to generate an output having a negative voltage from an input having a positive voltage comprising an input node configured to receive an alternating signal, an output node for outputting an output voltage of the generator and a ground node, a switching element configured to provide a conductive and non-conductive flow path between a first terminal and a second terminal in response to a control signal; a control element adapted to control the flow of current therethrough between a first terminal and a second terminal.

Abstract: A method for operating a cutting dredger in open water, in particular to control a ground reaction force during dredging operations, the dredger including; a floating body, an elongate cutter ladder having a cutting head at its lowerable free end for dredging, which cutter ladder is hingeably coupled to the floating body and hingeable between an upwards position and a cutting position wherein the cutting head engages matter to be cut away at the floor of a body of water.

Abstract: An amplifier arrangement for amplifying an alternating signal, comprising an amplifier and an adaptive biasing circuit, the amplifier configured to receive an alternating signal for amplification and a bias signal for biasing the amplifier from the adaptive biasing circuit, the adaptive biasing circuit comprising a PTAT circuit wherein the PTAT circuit is configured to receive the alternating signal and modulate the bias signal based on the alternating signal.

Abstract: A disposable pull-on garment is disclosed, The pull-on garment comprises a ring-like elastic belt. The ring-like elastic belt comprises a front belt portion and a back belt portion comprising a belt layer and a belt elastic material joined to the belt layer. Each ring-like elastic belt portion has a central panel, and left and right side panels contiguous with its central panel. The central panel of the front belt portion is joined to the front waist panel of the absorbent main body. The central panel of the back belt portion is joined to the back waist panel of the absorbent main body. The respective left and right side panels of the front belt portion and the back belt portion are joined together at or adjacent to the respective left and right side edges to form the waist opening and the two leg openings. The longitudinal lengths of the side panels of the back belt portion are greater than the longitudinal lengths of the respective side panels of the front belt portion.

Abstract: A device fixed to a first mast cooperates with a contact area located on the outside face of a second mast sliding substantially coaxially in the first mast. The device includes guide units including a roller mounted free to rotate about an axis orthogonal to the axis of the masts, a pad with a bearing face, and a device for displacing the axis of the roller perpendicular to the contact area of the mast, as a function of forces applied by the mast on the roller. The bearing area of the unit on the mast is thus formed by the roller only, or the roller and the pad.

Abstract: The present invention relates to a plastic comprising zinc sulphide and to its use.

Abstract: A package for a die comprising a thermally conducting carrier; a dielectric frame on the carrier, the frame having a recess therein for receiving a die; an electrically insulating lid adapted to be positioned on the frame to cover the recess, the lid having dimensions such that when covering the recess a portion of the lid extends beyond the frame creating at least one overhang; the frame having at least one electrically conducting frame path; and the lid having a corresponding electrically conducting lid path arranged such that when the lid is positioned on the frame a portion of the lid path overlies the frame path, the lid path extending onto the overhang beyond the frame.

Abstract: The invention relates to a pharmaceutical composition, use, or method in the treatment of Irritable Bowel Syndrome (IBS) characterized by mixed or alternating bowel habits based on a modification of the Rome II criteria (IBS-M), with 5-hydroxytryptamine type-4 receptor agonists (5-HT4 agonists), in particular tegaserod.

Abstract: A device fixed to a first mast cooperates with a contact area located on the outside face of a second mast sliding substantially coaxially in the first mast. The device includes guide units including a roller mounted free to rotate about an axis orthogonal to the axis of the masts, a pad with a bearing face, and a device for displacing the axis of the roller perpendicular to the contact area of the mast, as a function of forces applied by the mast on the roller. The bearing area of the unit on the mast is thus formed by the roller only, or the roller and the pad.

Abstract: The invention relates to a service module for factories producing aluminium by fusion electrolysis. The turret (9) of the inventive service module (7) is provided with a determined tool set, wherein each tool (101, 102, 103) is mounted on a telescopic arm (111, 112, 113) which is fixed to the turret (9) by a hinge support (121, 122, 123) which enables said telescopic arm to be perpendicularly movable with respect to a determined hinge point without rotating around the main axis thereof. Said telescopic arms are interconnected by a mechanical connection device (200) which maintains the relative angular deviation between the perpendicular movements thereof within a given tolerance range. Said invention makes it possible to bring the tools closer without striking each other during the use thereof.

Abstract: A method of assembling a hinge conveyor chain includes providing adjacent conveyor links formed from a ferritic-pearlitic stainless steel, wherein the adjacent links have interdigitating link ends with openings for receiving a pin, and inserting a pin having a radially outwardly facing surface formed from a steel alloy with more than 0.6 wt. % of carbon and more than 12 wt. % of Cr through the openings of the interdigitating link ends to pivotally link the adjacent links.

Abstract: A chain module according to the invention comprises at least one link from ferritic-pearlitic stainless steel and at least one chain pin, which chain pin comprises an outwardly facing surface formed from a steel alloy which is substantially non-seizing to the ferritic-pearlitic stainless steel of said link. Preferably, the chain pin comprises a steel alloy with more than 0.6 wt. % of carbon and more than 12 wt. % of chromium.

Abstract: A chain module according to the invention comprises at least one link from ferritic-pearlitic stainless steel and at least one chain pin, which chain pin comprises an outwardly facing surface formed from a steel alloy which is substantially non-seizing to the ferritic-pearlitic stainless steel of said link. Preferably, the chain pin comprises a steel alloy with more than 0.6 wt. % of carbon and more than 12 wt. % of chromium.