Patents by Inventor Stephane Debono

Stephane Debono has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100234292
    Abstract: The present invention relates to a method of assessing a propensity of clinical outcome for a female mammal suffering from breast cancer in view of the expression of specific nucleic acid sequences in a biological sample.
    Type: Application
    Filed: April 16, 2008
    Publication date: September 16, 2010
    Applicants: IPSOGEN, INSERM - INSTITUT NATIONAL DE LA SANTE ET DE LA RE CHECHE MEDICALE, INSTITUT PAOLI-CALMETTES
    Inventors: Francois Bertucci, Daniel Birnbaum, Patrice Viens, Vincent Fert, Fabienne Hermitte, Stephane Debono, Stephane Deraco, Nathalie Borie, Fanny Piette
  • Publication number: 20090092983
    Abstract: A method for analyzing differential gene expression associated with breast tumor is based on the analysis of the over-expression or under-expression of polynucleotide sequences in a biological sample. The analysis includes the detection of the over-expression of at least one polynucleotide sequence(s), subsequence(s) or complement(s) thereof selected from predefined polynucleotide sequence sets.
    Type: Application
    Filed: September 17, 2008
    Publication date: April 9, 2009
    Inventors: Daniel Birnbaum, Francois Bertucci, Jocelyne Jacquemier, Stephane Debono, Nathalie Borie, Christophe Ginestier
  • Publication number: 20050287544
    Abstract: Differential gene expression associated with histopathologic features of colorectal disease can be performed with nucleic acid arrays. Such arrays can comprise a pool of polynucleotide sequences from colon tissues, and the detection of the overexpression or underexpression of polynucleotide sequences (or subsequences or complements thereof) from this pool can provide information relating to the detection, diagnosis, stage, classification, monitoring, prediction, prevention or treatment of colorectal disease.
    Type: Application
    Filed: December 1, 2004
    Publication date: December 29, 2005
    Inventors: Francois Bertucci, Remi Houlgatte, Daniel Birnbaum, Stephane Debono
  • Publication number: 20050221398
    Abstract: A method for analyzing differential protein expression associated with histopathologic features of breast disease including detecting overexpression or underexpression of a pool of proteins in breast tissues or cells, the pool including at lease one of a protein set including Afadin, Aurora A, a-Catenin, b-Catenin, BCL2, Cyclin D1, Cyclin E, Cytokeratin 5/6, Cytokeratin 8/18, E-Cadherin, EGFR, ERBB2, ERBB3, ERBB4, Estrogen receptor, FGFR1, FHIT, GATA3, Ki67, Mucin 1, P53, P-Cadherin, Progesterone receptor, TACC1, TACC2, TACC3, Cytokeratin 6, Cytokeratin 18, Ang1, AuroraB, BCRP1, CathepsinD, CD10, CD44, CK14, Cox2, FGF2, GATA4, Hif1a, MMP9, MTA1, NM23, NRG1a, NRG1beta, P27, Parkin, PLAU, S100, SCRIBBLE, Smooth Muscle Actin, THBS1 and TIMP1.
    Type: Application
    Filed: January 18, 2005
    Publication date: October 6, 2005
    Applicants: Ipsogen, SAS, a corporation of France, INSERM, a corporation of France, Institut Paoli-Calmettes, a corporation of France
    Inventors: Jocelyne Jacquemier, Francois Bertucci, Daniel Birnbaum, Stephane Debono, Rebecca Tagett
  • Publication number: 20050089899
    Abstract: The present invention relates to a method for analyzing differential gene expression associated with breast tumor, based on the analysis of the over-expression or under-expression of polynucleotide sequences in a biological sample. The analysis comprises the detection of the over-expression of at least one polynucleotide sequence(s), subsequence(s) or complement(s) thereof selected from predefined polynucleotide sequence sets.
    Type: Application
    Filed: August 27, 2004
    Publication date: April 28, 2005
    Inventors: Daniel Birnbaum, Francois Bertucci, Jocelyne Jacquemier, Stephane Debono, Nathalie Borie, Christophe Ginestier