Patents by Inventor Stephane Dumas

Stephane Dumas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for collagen imaging
    Patent number: 9386938
    Abstract: Diagnostic compositions and methods for imaging and/or assessing collagen are described. The diagnostic compositions can include collagen binding peptides.
    Type: Grant
    Filed: September 12, 2011
    Date of Patent: July 12, 2016
    Assignee: Collagen Medical, LLC
    Inventors: Peter D. Caravan, Andrew Kolodziej, Zhaoda Zhang, Stephane Dumas, Biplab Kumar Das, Vincent Jacques, Richard Looby, Steffi K. Koerner, Wei-Chuan Sun, David R. Buckler, Aida Abujoub, Aaron K. Sato
  • Methods for Collagen Imaging
    Publication number: 20120114557
    Abstract: Diagnostic compositions and methods for imaging and/or assessing collagen are described. The diagnostic compositions can include collagen binding peptides.
    Type: Application
    Filed: September 12, 2011
    Publication date: May 10, 2012
    Applicant: COLLAGEN MEDICAL, LLC
    Inventors: Peter D. Caravan, Andrew Kolodziej, Zhaoda Zhang, Stephane Dumas, Biplab Kumar Das, Vincent Jacques, Richard Looby, Steffi K. Koerner, Wei-Chuan Sun, David R. Buckler, Aida Abujoub, Aaron K. Sato
  • Methods of collagen imaging
    Patent number: 8034898
    Abstract: Diagnostic compositions and methods for imaging and/or assessing collagen are described. The diagnostic compositions can include collagen binding peptides.
    Type: Grant
    Filed: December 29, 2006
    Date of Patent: October 11, 2011
    Assignee: Collagen Medical, LLC
    Inventors: Peter D. Caravan, Andrew Kolodziej, Zhaoda Zhang, Stephane Dumas, Biplab Kumar Das, Vincent Jacques, Richard Looby, Steffi K. Koerner, Wei-Chuan Sun, David R. Buckler, Aida Abujoub, Aaron K. Sato
  • Peptide-based multimeric targeted contrast agents
    Patent number: 7927581
    Abstract: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.
    Type: Grant
    Filed: April 4, 2005
    Date of Patent: April 19, 2011
    Assignee: Factor 1A, LLC
    Inventors: Zhaoda Zhang, John C. Amedio, Peter D. Caravan, Stephane Dumas, Andrew Kolodziej, Thomas J. McMurry
  • METHODS OF MYOCARDIAL IMAGING
    Publication number: 20080058636
    Abstract: Diagnostic compositions and methods for imaging collagen and/or assessing myocardial perfusion are described. The diagnostic compositions can include collagen binding peptides.
    Type: Application
    Filed: December 29, 2006
    Publication date: March 6, 2008
    Inventors: Peter Caravan, Andrew Kolodziej, Zhaoda Zhang, Stephane Dumas, Biplab Das, Vincent Jacques, Richard Looby, Steffi Koerner, Wei-Chuan Sun, David Buckler, Aida Abujoub, Aaron Sato
  • METHODS OF COLLAGEN IMAGING
    Publication number: 20080044360
    Abstract: Diagnostic compositions and methods for imaging and/or assessing collagen are described. The diagnostic compositions can include collagen binding peptides.
    Type: Application
    Filed: December 29, 2006
    Publication date: February 21, 2008
    Inventors: Peter Caravan, Andrew Kolodziej, Zhaoda Zhang, Stephane Dumas, Biplab Das, Vincent Jacques, Richard Looby, Steffi Koerner, Wei-Chuan Sun, David Buckler, Aida Abujoub, Aaron Sato
  • COLLAGEN BINDING PEPTIDES
    Publication number: 20070293656
    Abstract: Peptides capable of binding to extracellular matrix proteins, such as collagen, are described, including their use in diagnostic and therapeutic applications.
    Type: Application
    Filed: December 29, 2006
    Publication date: December 20, 2007
    Inventors: Peter Caravan, Andrew Kolodziej, Biplab Das, Zhaoda Zhang, Stephane Dumas, Steffi Koerner, Wei-Chuan Sun, David Buckler, Aida Abujoub, Aaron Sato
  • Peptide-Based Multimeric Targeted Contrast Agents
    Publication number: 20070185311
    Abstract: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.
    Type: Application
    Filed: November 29, 2006
    Publication date: August 9, 2007
    Applicant: EPIX PHARMACEUTICALS, INC.
    Inventors: Zhaoda Zhang, John Amedio, Peter Caravan, Stephane Dumas, Andrew Kolodziej, Thomas McMurry
  • Peptide-based multimeric targeted contrast agents
    Patent number: 7238341
    Abstract: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.
    Type: Grant
    Filed: February 25, 2004
    Date of Patent: July 3, 2007
    Assignee: Epix Pharmaceuticals, Inc.
    Inventors: Zhaoda Zhang, John C. Amedio, Peter D. Caravan, Stephane Dumas, Andrew Kolodziej, Thomas J. McMurry
  • Polypeptide conjugates with extended circulating half-lives
    Patent number: 7186797
    Abstract: The present invention relates to compounds and methods for synthesizing compounds wherein the compounds exhibit extended circulating half-life in the blood. The increase in circulating half-life is achieved by conjugating polypeptides to binding groups that exhibit high affinity for human serum albumin.
    Type: Grant
    Filed: August 9, 2002
    Date of Patent: March 6, 2007
    Assignee: Epix Pharmaceuticals, Inc.
    Inventors: Theodore R. West, Thomas J McMurry, Stephane Dumas, Andrew Kolodziej
  • Hydroxypyridinone derivatives, metal complexes thereof and the use thereof for preparing conjugates with biomolecules
    Publication number: 20070003484
    Abstract: The invention relates to hydroxypyridinone derivatives, their metal complexes, their preparation and their use for preparing conjugates with biomolecules. The conjugates are suitable as contrast agents in NMR diagnosis. A high relaxivity is achieved and the NMRD maximum is raised through a specific design of the ligands.
    Type: Application
    Filed: December 20, 2005
    Publication date: January 4, 2007
    Inventors: Heribert Schmitt-Willich, Heiko Schirmer, Johannes Platzek, Stephane Dumas, Vincent Jacques, Thomas Brumby, Detlev Suelzle, Bernd Misselwitz
  • Conjugates of hydroxypyridinone derivative metal complexes with biomolecules and their use for MRI diagnosis
    Publication number: 20060292079
    Abstract: The invention relates to conjugates of hydroxypyridinone derivative metal complexes and to their preparation. The conjugates are suitable as contrast agents in NMR diagnosis. A high relaxivity is achieved and the NMRD maximum is raised through a specific design of the ligands.
    Type: Application
    Filed: December 20, 2005
    Publication date: December 28, 2006
    Inventors: Heribert Schmitt-Willich, Heiko Schirmer, Johannes Platzek, Stephane Dumas, Vincent Jacques, Thomas Brumby, Detlev Suelzle, Bernd Misselwitz
  • Bioactivated diagnostic imaging contrast agents
    Publication number: 20060275216
    Abstract: The present invention relates to improved diagnostic agents for Magnetic Resonance Imaging and optical imaging. In particular, this invention relates to MRI and optical imaging agents that allow for the sensitive detection of a specific bioactivity within a tissue. These agents are prodrug contrast agents which are bioactivated in vivo in the presence of the specific bioactivity. This invention also relates to pharmaceutical compositions comprising these agents and to methods of using the agents and compositions comprising the agents.
    Type: Application
    Filed: August 16, 2006
    Publication date: December 7, 2006
    Inventors: Randall Lauffer, Thomas McMurry, Stephen Dunham, Daniel Scott, David Parmelee, Stephane Dumas
  • Peptide-based multimeric targeted contrast agents
    Publication number: 20060039861
    Abstract: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.
    Type: Application
    Filed: April 4, 2005
    Publication date: February 23, 2006
    Inventors: Zhaoda Zhang, John Amedio, Peter Caravan, Stephane Dumas, Andrew Kolodziej, Thomas McMurry
  • Peptide-based multimeric targeted contrast agents
    Publication number: 20050074411
    Abstract: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.
    Type: Application
    Filed: February 25, 2004
    Publication date: April 7, 2005
    Inventors: Zhaoda Zhang, John Amedio, Peter Caravan, Stephane Dumas, Andrew Kolodziej, Thomas McMurry
  • Polypeptide conjugates with extended circulating half-lives
    Publication number: 20040254119
    Abstract: The present invention relates to compounds and methods for synthesizing compounds wherein the compounds exhibit extended circulating half-life in the blood. The increase in circulating half-life is achieved by conjugating polypeptides to binding groups that exhibit high affinity for human serum albumin.
    Type: Application
    Filed: July 15, 2004
    Publication date: December 16, 2004
    Inventors: Theodore R. West, Thomas J McMurry, Stephane Dumas, Andrew Kolodziej
  • Bioactivated diagnostic imaging constrast agents
    Publication number: 20040156785
    Abstract: The present invention relates to improved diagnostic agents for Magnetic Resonance Imaging and optical imaging. In particular, this invention relates to MRI and optical imaging agents that allow for the sensitive detection of a specific bioactivity within a tissue. These agents are prodrug contrast agents which are bioactivated in vivo in the presence of the specific bioactivity. This invention also relates to pharmaceutical compositions comprising these agents and to methods of using the agents and compositions comprising the agents.
    Type: Application
    Filed: January 16, 2004
    Publication date: August 12, 2004
    Applicant: Epix Medical , Inc., a Delaware corporation
    Inventors: Randall B. Lauffer, Thomas J. McMurry, Stephen O. Dunham, Daniel M. Scott, David J. Parmelee, Stephane Dumas
  • Targeting multimeric imaging agents through multilocus binding
    Publication number: 20040005274
    Abstract: The present invention relates to contrast agents for diagnostic imaging. In particular, this invention relates to novel multimeric compounds which exhibit improved relaxivity properties upon binding to endogenous proteins or other physiologically relevant sites.
    Type: Application
    Filed: May 27, 2003
    Publication date: January 8, 2004
    Applicant: Epix Medical, Inc., a Delaware corporation
    Inventors: Randall B. Lauffer, Thomas J. McMurry, Stephane Dumas, Andrew Kolodziej, John C. Amedio, Peter D. Caravan, Zhaoda Zhang, Shrikumar Nair, Robert M. Weisskoff
  • Targeting multimeric imaging agents through multilocus binding
    Patent number: 6652835
    Abstract: The present invention relates to contrast agents for diagnostic imaging. In particular, this invention relates to novel multimeric compounds which exhibit improved relaxivity properties upon binding to endogenous proteins or other physiologically relevant sites. The compounds consist of: a) two or more Image Enhancing Moieties (IEMs) (or signal-generating moiety) comprising multiple subunits; b) two or more Target Binding Moieties (TBMs), providing for in vivo localization and multimer rigidification; and c) a scaffold framework for attachment of the above moieties. d) optional linkers for attachment of the IEMs to scaffold. This invention also relates to pharmaceutical compositions comprising these compounds and to methods of using the compounds and compositions for contrast enhancement of diagnostic imaging.
    Type: Grant
    Filed: July 28, 2000
    Date of Patent: November 25, 2003
    Assignee: Epix Medical, Inc.
    Inventors: Randall B. Lauffer, Thomas J. McMurry, Stephane Dumas, Andrew Kolodziej, John Amedio, Peter Caravan, Zhaoda Zhang
  • Peptide-based multimeric targeted contrast agents
    Publication number: 20030180222
    Abstract: Peptides and peptide-targeted multimeric contrast agents are described, as well as methods of making and using the contrast agents.
    Type: Application
    Filed: July 30, 2002
    Publication date: September 25, 2003
    Inventors: Zhaoda Zhang, John C. Amedio, Peter D. Caravan, Stephane Dumas, Andrew Kolodziej, Thomas J. McMurry