Patents by Inventor Stephane Jean Marie Olivier
Stephane Jean Marie Olivier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 8753588Abstract: Underdrain design for a multiwell device that when fixed to the device (either as an integral or removable component thereof), allows for adequate venting during filtration, minimizes or prevents air lock, and has improved structural integrity. Also disclosed is a laboratory device designed particularly for a multiplate format that includes a plate or tray having a plurality of wells, and an underdrain in fluid communication with each of the plurality of wells. The underdrain can be a separate, removable piece, or can be an integral unitary structure with the plate or tray forming a one-piece design. The design is preferably in compliance with SBS format.Type: GrantFiled: October 8, 2004Date of Patent: June 17, 2014Assignee: EMD Millipore CorporationInventors: Kenneth G. Desilets, Stephane Jean Marie Olivier, Christopher A. Scott
-
Patent number: 8182766Abstract: The present invention relates to a multiwell plate having a series of wells, each well having an inner bore, an open top and a bottom, the bottom being sealed with a liquid permeable filter, and an insert contained within the inner bore of each well, each insert having an outer dimension the same or larger than that of the inner bore and a through bore of a dimension less than that of the outer dimension of the insert. The use of inserts allows one to take a standard one-piece plate design with a heat sealed membrane and arrange for a universal plate format. The insert may act as a base for an extension plate that can be adhered, heat sealed or overmolded over the plate top and insert top to form a deep well plate. The plate conforms to the Society of Biological Standards Microplate Standards. Additionally, the inserts may be configured to give one a different well diameter (smaller, tapered, etc), to include various media such as chromatography resins, to include multiple layers of membrane and the like.Type: GrantFiled: February 8, 2010Date of Patent: May 22, 2012Assignee: EMD Millipore CorporationInventors: Stephane Jean Marie Olivier, Gerard Muller, Jeffery S. Busnach
-
Publication number: 20100233034Abstract: The present invention relates to a multiwell plate having a series of wells, each well having an inner bore, an open top and a bottom, the bottom being sealed with a liquid permeable filter, and an insert contained within the inner-bore of each well, each insert having an outer dimension the same or larger than that of the inner bore and a through bore of a dimension less than that of the outer dimension of the insert. The use of inserts allows one to take a standard one-piece plate design with a heat sealed membrane and arrange for a universal plate format. The insert may act as a base for an extension plate that can be adhered, heat sealed or overmolded over the plate top and insert top to form a deep well plate. The plate conforms to the Society of Biological Standards Microplate Standards. Additionally, the inserts may be configured to give one a different well diameter (smaller, tapered, etc), to include various media such as chromatography resins, to include multiple layers of membrane and the like.Type: ApplicationFiled: February 8, 2010Publication date: September 16, 2010Applicant: Millipore CorporationInventors: Stephane Jean Marie Olivier, Gerard Muller, Jeffrey S. Busnach
-
Patent number: 7658886Abstract: The present invention relates to a multiwell plate having a series of wells, each well having an inner bore, an open top and a bottom, the bottom being sealed with a liquid permeable filter, and an insert contained within the inner bore of each well, each insert having an outer dimension the same or larger than that of the inner bore and a through bore of a dimension less than that of the outer dimension of the insert. The use of inserts allows one to take a standard one-piece plate design with a heat sealed membrane and arrange for a universal plate format. The insert may act as a base for an extension plate that can be adhered, heat sealed or overmolded over the plate top and insert top to form a deep well plate. The plate conforms to the Society of Biological Standards Microplate Standards. Additionally, the inserts may be configured to give one a different well diameter (smaller, tapered, etc), to include various media such as chromatography resins, to include multiple layers of membrane and the like.Type: GrantFiled: May 4, 2004Date of Patent: February 9, 2010Assignee: Millipore CorporationInventors: Stéphane Jean Marie Olivier, Gerard Muller, Jeffrey S. Busnach
-
Patent number: 7063216Abstract: The present invention provides an underdrain having an improved spout. The underdrain has particular utility in the construction of both single-well and microarray filtration devices. In a principal embodiment, the underdrain is characterized by its incorporation of a straight-walled, roughly-textured spout, the spout being provided with microhole(s) at a terminal end thereof for the discharge of fluid conducted through the underdrain. An array comprising several of such underdrains can be mated with a corresponding array of wells, with separation material (e.g., membrane material) provided therebetween. The resultant microarray filtration device can be used for conducting several fluid assays contemporaneously with, for example, good “pendant drop” control and low “cross-talk”.Type: GrantFiled: September 4, 2003Date of Patent: June 20, 2006Assignee: Millipore CorporationInventors: Joseph P. Lane, Louis L. Bonhomme, Douglas A. Boucher, Richard T. Burnham, Kenneth G. Desilets, Luc Lirot, Stéphane Jean Marie Olivier, Steven D. Sheridan
-
Publication number: 20040247490Abstract: The present invention relates to a multiwell plate having a series of wells, each well having an inner bore, an open top and a bottom, the bottom being sealed with a liquid permeable filter, and an insert contained within the inner bore of each well, each insert having an outer dimension the same or larger than that of the inner bore and a through bore of a dimension less than that of the outer dimension of the insert. The use of inserts allows one to take a standard one-piece plate design with a heat sealed membrane and arrange for a universal plate format. The insert may act as a base for an extension plate that can be adhered, heat sealed or overmolded over the plate top and insert top to form a deep well plate. The plate conforms to the Society of Biological Standards Microplate Standards. Additionally, the inserts may be configured to give one a different well diameter (smaller, tapered, etc), to include various media such as chromatography resins, to include multiple layers of membrane and the like.Type: ApplicationFiled: May 4, 2004Publication date: December 9, 2004Inventors: Stephane Jean Marie Olivier, Gerard Muller, Jeffrey S. Busnach
-
Publication number: 20040089615Abstract: An evaporation control device for a multiwell plate system that reduces the evaporation from the plate such as during centrifugation. Preferably it substantially conforms to the shape and size of the plate system. A first design is a sheet material interposed between the adjacent surface so f the plates. A second is a cover that has a skirt that extends downward from the top of the plate system to at least a point below the filter plate/collection plate interface. Preferably, the cover has a skirt that extends down to approximately the bottom of the collection plate and is formed of thin plastic that even more preferably has been vacuum formed into shape. A third embodiment is a combination of the two control devices.Type: ApplicationFiled: September 9, 2003Publication date: May 13, 2004Inventors: Alan Weiss, Stephane Jean Marie Olivier, John B. Lynch, Kenneth G. DeSilets
-
Publication number: 20040009580Abstract: The combination of a supported UF membrane having low non-specific binding (NSB) and high protein retention of the tested chemical entity (CE) in a device that is SBS complaint. The membrane is heat sealed to form one or more integral wells that are used to reduce NSB and improve protein retention and provides a simple, flexible way to reduce CE, such as drug and drug candidate (and other small molecule) NSB so that drug binding studies may more closely predict the behavior of these compounds in vivo.Type: ApplicationFiled: June 6, 2003Publication date: January 15, 2004Inventors: John B. Lynch, Michele Dumon, Alan Weiss, Kenneth G. Desilets, Stephane Jean Marie Olivier