Patents by Inventor Stephane Palfi

Stephane Palfi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9775573
    Abstract: A peroperative probe for guiding a manual excision tool. The probe includes a detection head, an optical fiber for the reception and guidance of a signal emitted by radioactive tracers and fluorescent molecules in a tissue area, a photo-detector for converting the emitted signal into an electrical signal, a transmitter for transmitting information carried by the electrical signal to an analysis equipment, and a fastener for attaching the probe onto the manual excision tool, so that the excision tool can be used to remove a portion of tissue from the tissue area emitting the signal.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: October 3, 2017
    Assignee: Centre National De La Recherche Scientifique
    Inventors: Laurent Menard, Sebastien Bonzom, Yves Charon, Marie-Alix Duval, Francoise Lefebvre-Bouvet, Stephane Palfi, Laurent Pinot, Rainer Siebert, Stephanie Pitre
  • Publication number: 20150182177
    Abstract: A preoperative probe for guiding a manual excision tool. The probe includes a detection head, an optical fibre for the reception and guidance of a signal emitted by radioactive tracers and fluorescent molecules in a tissue area, a photo-detector for converting the emitted signal into an electrical signal, a transmitter for transmitting information carried by the electrical signal to an analysis equipment, and a fastener for attaching the probe onto the manual excision tool, so that the excision tool can be used to remove a portion of tissue from the tissue area emitting the signal.
    Type: Application
    Filed: December 23, 2014
    Publication date: July 2, 2015
    Inventors: Laurent Menard, Sebastien Bonzom, Yves Charon, Marie-Alix Duval, Francoise Lefebvre, Stephane Palfi, Laurent Pinot, Rainer Siebert, Stephanie Pitre
  • Publication number: 20120295960
    Abstract: Provided is an improved treatment for Parkinson's Disease where the efficacy of L-Dopa treatment is increased by including gene therapy in the treatment regimen. The combination therapy results in long-term improvements in response to L-Dopa and diminished side effects caused by L-Dopa.
    Type: Application
    Filed: January 9, 2012
    Publication date: November 22, 2012
    Inventors: Stephane Palfi, Kyriacos A. Mitrophanous, Scott Ralph
  • Publication number: 20110269826
    Abstract: The present invention provides methods for: (i) treating and/or preventing Parkinson's disease in a subject without causing cognitive impairment by using dopamine replacement gene therapy to maintain or restore constant physiological dopaminergic tone in both the dorsal and ventral striatum of the subject; (ii) normalising neuronal electrical activity in basal ganglia and/or subthalamic nucleus in a Parkinson's disease subject; and (iii) treating and/or preventing dyskinesias associated with oral L-dopa administration in a Parkinson's disease subject by administration of a vector system for dopamine replacement gene therapy to the subject.
    Type: Application
    Filed: November 11, 2009
    Publication date: November 3, 2011
    Applicant: OXFORD BIOMEDICA (UK) LIMITED
    Inventors: Susan M. Kingsman, Alan J. Kingsman, Scott Ralph, Kyriacos A. Mitrophanous, Stephane Palfi, Bechir Jarraya