Patents by Inventor Stephane Prost

Stephane Prost has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9623015
    Abstract: Provided are methods for eliminating hematologic cancer stem cells in vivo, and thus preventing cancer relapse. The methods comprise a Signal Transducer and Activator of Transcription 5 (STAT5) antagonist (e.g., a PPAR? agonist) after the patient has had ana initial course of treatment with an anti-cancer agent (e.g., a TKI), to eliminate residual cancer stem cells which cause relapse.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: April 18, 2017
    Assignee: Commissariat à L'Energie Atomique et aux Energies Alternatives (CEA)
    Inventors: Stéphane Prost, Marek Kirszenbaum, Mikael Le Dantec, Philippe Rousselot, Philippe Leboulch
  • Publication number: 20150265588
    Abstract: Provided are methods for eliminating hematologic cancer stem cells in vivo, and thus preventing cancer relapse. The methods comprise a Signal Transducer and Activator of Transcription 5 (STAT5) antagonist (e.g., a PPARy agonist) after the patient has had ana initial course of treatment with an anti-cancer agent (e.g., a TKI), to eliminate residual cancer stem cells which cause re lapse.
    Type: Application
    Filed: November 5, 2013
    Publication date: September 24, 2015
    Inventors: Stéphane Prost, Marek Kirszenbaum, Mikael Le Dantec, Philippe Rousselot, Philippe Leboulch
  • Publication number: 20070148686
    Abstract: The invention concerns a protein present at the surface of hematopoietic stem cells of the lymphoid cell line and mature NK cells, the corresponding isolated cDNA sequence and their uses as marker of said cells and for preparing antibodies directed against said protein. The invention also concerns the uses of said antibodies for selecting cells expressing at their surface said protein.
    Type: Application
    Filed: March 5, 2007
    Publication date: June 28, 2007
    Inventors: Marek Kirszenbaum, Magali Le Discorde, Stephane Prost
  • Patent number: 7235632
    Abstract: The invention concerns a protein present at the surface of hematopoietic stem cells of the lymphoid cell line and mature NK cells, the corresponding isolated cDNA sequence and their uses as marker of said cells and for preparing antibodies directed against said protein. The invention also concerns the uses of said antibodies for selecting cells expressing at their surface said protein.
    Type: Grant
    Filed: November 10, 2000
    Date of Patent: June 26, 2007
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Marek Kirszenbaum, Magali Le Discorde, Stéphane Prost
  • Patent number: 7160145
    Abstract: The invention concerns an interconnect device in particular for connection and/or line terminals arranged on-line, comprising first and second interconnect combs facing each other and comprising each a connecting bar, and teeth, extending substantially perpendicularly from the connecting bar, the device comprising elastic teeth and rigid teeth. The teeth of each of the first and second combs are alternately rigid and elastic. The elastic teeth and the rigid teeth of the first comb are located respectively opposite the rigid teeth and the elastic teeth of the second comb.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: January 9, 2007
    Assignee: ABB Entrelec
    Inventors: Sylvain Barrat, Stéphane Prost
  • Publication number: 20060110975
    Abstract: The invention concerns an interconnect device in particular for connection and/or line terminals arranged on-line, comprising first and second interconnect combs facing each other and comprising each a connecting bar, and teeth, extending substantially perpendicularly from the connecting bar, the device comprising elastic teeth and rigid teeth. The teeth of each of the first and second combs are alternately rigid and elastic. The elastic teeth and the rigid teeth of the first comb are located respectively opposite the rigid teeth and the elastic teeth of the second comb.
    Type: Application
    Filed: November 12, 2003
    Publication date: May 25, 2006
    Applicant: ABB ENTRELEC
    Inventors: Sylvain Barrat, Stephane Prost
  • Patent number: 6733330
    Abstract: This terminal block comprises; an insulating casing in which at least one housing for accommodating a connector, which can be plugged into the housing in a direction (D), is provided, means for locking the connector to the casing. The locking means comprise: at least one locking arm which: is secured to the casing, swings around an axis of rotation (&Dgr;), between a withdrawal position and a locking position, is equipped with a catching element intended to cooperate in the locking position with a complementary catching element of the connector, means for immobilizing the arm in the locking position.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: May 11, 2004
    Assignee: Entrelec S.A.
    Inventors: Stephane Prost, Sylvain Barrat
  • Patent number: 6595808
    Abstract: This spring is made of an elastic leaf bent in such a way as to exhibit a pressing branch (4) and a moving branch (6) which are connected by an elastic arc (8) to the pressing branch, an opening (18) being made in the moving branch near its free end and being intended to accommodate an end of the conductor that is to be connected. The opening (18) transversely has a variable width, this width being greater at the end nearest the free end of the moving branch (6).
    Type: Grant
    Filed: May 1, 2002
    Date of Patent: July 22, 2003
    Assignee: Entrelec SA
    Inventors: Stephane Prost, Franck Da Silva
  • Publication number: 20030022551
    Abstract: This terminal block comprises;
    Type: Application
    Filed: July 11, 2002
    Publication date: January 30, 2003
    Applicant: Entrelec S.A.
    Inventors: Stephane Prost, Sylvain Barrat
  • Publication number: 20020123274
    Abstract: This spring is made of an elastic leaf bent in such a way as to exhibit a pressing branch (4) and a moving branch (6) which are connected by an elastic arc (8) to the pressing branch, an opening (18) being made in the moving branch near its free end and being intended to accommodate an end of the conductor that is to be connected.
    Type: Application
    Filed: May 1, 2002
    Publication date: September 5, 2002
    Applicant: ENTRELEC S.A.
    Inventors: Stephane Prost, Franck Da Silva
  • Publication number: 20020002017
    Abstract: Spring intended for making an electrical connection This spring is made of an elastic leaf bent in such a way as to exhibit a pressing branch (4) and a moving branch (6) which are connected by an elastic arc (8) to the pressing branch, an opening (18) being made in the moving branch near its free end and being intended to accommodate an end of the conductor that is to be connected.
    Type: Application
    Filed: May 21, 2001
    Publication date: January 3, 2002
    Applicant: ENTRELEC S.A.
    Inventors: Stephane Prost, Franck Da Silva
  • Patent number: 6196883
    Abstract: This spring allows an electrical connection to a stripped wire to be made in a terminal strip. It has bearing branch intended to bear against a conducting fixed part and a rear branch, facing the bearing branch, linked via a springy linking region to the latter and the free end of which is curved toward the bearing branch in order to form a moveable pinching branch having, on the same side as its free end, an appreciably plane part provided with an opening intended for passage of the conducting fixed part and of the stripped wire in such a way that the edge of the opening lying on the same side as the free end of the moveable pinching branch keeps the stripped end of the wire pressed against the conducting fixed part. A linking region springingly links the two branches. On the opposite side from the rear branch, the bearing branch is provided with a guiding region which extends parallel to the pinching branch.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: March 6, 2001
    Assignee: Entrelec S.A.
    Inventors: Bernard Bechaz, Stéphane Prost, Philippe France
  • Patent number: 6183288
    Abstract: This device is made from a flat resilient material, which has a first branch intended to bear against a fixed conducting part of a connection terminal, a moving sharply-angled second branch having, on the side of its free end, an approximately planar part provided with an opening intended for passage of the end of a cable to be connected and a part facing the first branch, as well as a linking region which joins the two branches, thus forming a loop. Each branch has a part which is concave toward the outside of the loop and the two concave parts are approximately facing each other and form a narrows inside the loop.
    Type: Grant
    Filed: September 1, 1999
    Date of Patent: February 6, 2001
    Assignee: Entrelec S.A.
    Inventors: Sylvain Barrat, Bernard Bechaz, Philippe France, Stéphane Prost