Abstract: The invention relates, amongst others, to a method for determining an FFR-related parameter value, comprising: providing a CT image comprising coronary arteries obtained from coronary CT angiography, CCTA; extracting, from said CT image and for each of said coronary arteries, a respective centerline; and determining, based at least on a coronary artery model comprising said respective centerlines, said FFR-related parameter value; wherein said CT image is a 3D CT image comprising voxels, each voxel being associated with a radiodensity value, preferably a Hounsfield unit value; wherein said extracting of said respective centerlines comprises applying, on said 3D CT image comprising voxels, a first NN being a 3D NN trained with respect to the centerline; and wherein said determining of said FFR-related parameter value comprises applying, on said coronary artery model, a third NN trained with respect to FFR-related training data.

Abstract: An optical microscope digital image processing emulator or emulation is described in which a user input device is used to assist in the emulation of an operation of an optical microscope in a digital image processing system. The emulator or emulation is programmable via a library of processing functions stored in memory. The input device is adapted to generate control signals based on a user input, and to transfer the control signals to a processor, the processor being adapted to alter one or more parameters of the processing functions based on the control signals. Embodiments of the present invention emulate the same control and responsiveness found with an optical microscope on a digital pathology computer system, thereby improving the workflow of pathology specialists by allowing better and faster control over the way images are presented.