Patents by Inventor Stephane Yvon

Stephane Yvon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydroxyphenol derivatives, processes for the preparation thereof, pharmaceutical compositions them, and therapeutic uses thereof
    Patent number: 8653134
    Abstract: Compounds of the formula (I): in which A, R1, R2, X, Y and Z are defined in the description, the processes for the preparation of these compounds, the uses thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, and the pharmaceutical compositions comprising them.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: February 18, 2014
    Assignee: Merck Patent GmbH
    Inventors: Catherine Vidal, Nathalie Adje, Stéphane Yvon, Jean Jacques Zeiller
  • Specific caspase-10 inhibitors
    Patent number: 7829721
    Abstract: The invention relates to compounds of the general formula (I), and to their use as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: November 9, 2010
    Assignee: Merck Patent GmbH
    Inventors: Claude Lardy, Marc Lecomte, Catherine Vidal, Thierry Convard, Stéphane Yvon, Marie Noelle Denuault, Denis Descours
  • 1-indole-3-carboxylic acid derivatives and their use as PPAR agonists
    Patent number: 7754740
    Abstract: Compounds of the formula (1): in which A, R1, R2 and R3 are as defined in the description, the processes for the preparation of these compounds, the uses thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, and the pharmaceutical compositions comprising them.
    Type: Grant
    Filed: December 17, 2005
    Date of Patent: July 13, 2010
    Assignee: Merck Patent GmbH
    Inventors: Nathalie Adje, Didier Roche, Stéphane Yvon
  • Aroyl-O-piperidine derivatives for the treatment of diabetes-related problems
    Patent number: 7723358
    Abstract: The present invention relates to derivatives of aroyl-O-piperidine structure of the general formula (I): in which R1, R2, R3 and R4 are as defined in the description. Application of the compounds of the formula (I) to the treatment of hyper-triglyceridaemia, hypercholesterolaemia and dyslipidaemia, and to the prevention or treatment of obesity.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: May 25, 2010
    Assignee: Merck Patent GmbH
    Inventors: Philippe Guedat, Francois Collonges, Olivier Chevreuil, Hervé Dumas, Marie Noelle Denault, Stéphane Yvon, Peter Kane, Julia Lainton, Avril Robertson, Bernd Wendt
  • Carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia
    Patent number: 7482484
    Abstract: Disclosed are Compounds of formula I And methods of use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: January 27, 2009
    Assignee: Merck Patent GmbH
    Inventors: Nathalie Adje, Michel Brunet, Didier Roche, Jean-Jacques Zeiller, Stéphane Yvon, Valérie Guyard-Dangremont, Francis Contard, Daniel Guerrier, Gérard Ferrand, Yves Bonhomme
  • Novel Specific Caspase-10 Inhibitors
    Publication number: 20080255173
    Abstract: The invention relates to compounds of the general formula (I), and to their use as caspase-10 inhibitors, especially for the treatment of diabetic retinopathy.
    Type: Application
    Filed: November 2, 2005
    Publication date: October 16, 2008
    Inventors: Claude Lardy, Marc Lecomte, Catherine Vidal, Thierry Convard, Stephane Yvon, Marie Noelle Denuault, Denis Descours
  • Hydroxyphenol Derivatives, Processes For The Preparation Thereof, Pharmaceutical Compositions Them, And Therapeutic Uses Thereof
    Publication number: 20080161308
    Abstract: Compounds of the formula (I): in which A, R1, R2, X, Y and Z are defined in the description, the processes for the preparation of these compounds, the uses thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, and the pharmaceutical compositions comprising them.
    Type: Application
    Filed: December 22, 2005
    Publication date: July 3, 2008
    Inventors: Catherine Vidal, Nathalie Adje, Stephane Yvon, Jean Jacques Zeiller
  • 1H-Indole-3-Carboxylic Acid Derivatives And Their Use As Ppar Agonists
    Publication number: 20080114034
    Abstract: Compounds of the formula (1): in which A, R1, R2 and R3 are as defined in the description, the processes for the preparation of these compounds, the uses thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, and the pharmaceutical compositions comprising them.
    Type: Application
    Filed: December 17, 2005
    Publication date: May 15, 2008
    Inventors: Nathalie Adje, Didier Roche, Stephane Yvon
  • Aroyl-O-Piperidine Derivatives for the Treatment of Diabetes-Related Problems
    Publication number: 20070254919
    Abstract: The present invention relates to derivatives of aroyl-O-piperidine structure of the general formula (I): in which R1, R2, R3 and R4 are as defined in the description. Application of the compounds of the formula (I) to the treatment of hyper-triglyceridaemia, hypercholesterolaemia and dyslipidaemia, and to the prevention or treatment of obesity.
    Type: Application
    Filed: May 19, 2005
    Publication date: November 1, 2007
    Inventors: Philippe Guedat, Francois Collonges, Olivier Chevreuil, Herve Dumas, Marie Denault, Stephane Yvon, Peter Kane, Julia Lainton, Avril Robertson, Bernd Wendt
  • Novel carboxylic acids and derivatives for the treatment of and preventing diabetes and dyslipidaemia
    Publication number: 20060111445
    Abstract: The present invention relates to a compound of the formula ((I): in which: n is an integer chosen from 1, 2 and 3; Y represents O; N—OR9, in which R9 represents H or a saturated hydrocarbon-based aliphatic group; CR10R11, in which R10 and R11, which may be identical or different, represent H or a saturated hydrocarbon-based aliphatic group; R1 and R2, which may be identical or different, represent H or a saturated aliphatic hydrocarbon-based chain; or alternatively R1 and R2 together form an optionally substituted saturated aliphatic hydrocarbon-based chain; the radicals R3 and R4, which may be identical or different, take any of the is meanings given above for R1 and R2, or alternatively R1 and the group R4 borne by the carbon alpha to CR1R2 represent nothing and a double bond links the CR1R2 carbon to the alpha CR3R4 carbon; or alternatively one of the radicals R1 and R2 forms with one of the radicals R3 and R4 an optionally substituted saturated or unsaturated aliphatic hydrocarbon-based chain; one of the
    Type: Application
    Filed: December 16, 2003
    Publication date: May 25, 2006
    Inventors: Nathalie Adje, Michel Brunet, Didier Roche, Jean-Jacques Zeiller, Stephane Yvon, Valerie Guyard-Dangremont, Francis Contard, Daniel Guerrier, Gerard Ferrand