Patents by Inventor Stephanie Dougan

Stephanie Dougan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomaterials for combined radiotherapy and immunotherapy of cancer
    Patent number: 10835604
    Abstract: Compositions and methods for the radiological and immunotherapeutic treatment of cancer are provided. Metallic nanoparticles conjugated with an immunoadjuvant are dispersed within a biodegradable polymer matrix that can be implanted in a patient and released gradually. The implant may be configured as, or be a component of, brachytherapy spacers and applicators, or radiotherapy fiducial markers. The composition may be combined with marginless radiotherapy, allowing for lower doses of radiation and enhancing the immune response against cancer, including at non-irradiated sites.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: November 17, 2020
    Assignees: Northeastern University, Dana-Farber Cancer Institute, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Wilfred Ngwa, Rajiv Kumar, Gerassimos Makrigiorgos, Srinivas Sridhar, Stephanie Dougan
  • BIOMATERIALS FOR COMBINED RADIOTHERAPY AND IMMUNOTHERAPY OF CANCER
    Publication number: 20180271978
    Abstract: Compositions and methods for the radiological and immunotherapeutic treatment of cancer are provided. Metallic nanoparticles conjugated with an immunoadjuvant are dispersed within a biodegradable polymer matrix that can be implanted in a patient and released gradually. The implant may be configured as, or be a component of, brachytherapy spacers and applicators, or radiotherapy fiducial markers. The composition may be combined with marginless radiotherapy, allowing for lower doses of radiation and enhancing the immune response against cancer, including at non-irradiated sites.
    Type: Application
    Filed: August 15, 2016
    Publication date: September 27, 2018
    Applicants: Northeastern University, Dana-Farber Cancer Institute, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Wilfred Ngwa, Rajiv Kumar, Gerassimos Makrigiorgos, Srinivas Sridhar, Stephanie Dougan