Patents by Inventor Stephanie FANUCCHI

Stephanie FANUCCHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOMODULATION BY CONTROLLING ELR+ PROINFLAMMATORY CHEMOKINE LEVELS WITH THE LONG NON-CODING RNA UMLILO
    Publication number: 20190338280
    Abstract: The present invention relates to methods for modulating the production of ELR+ proinflammatory chemokines in a subject or a cell using either UMLILO IncRNA inhibitors to decrease production of ELR+ proinflammatory cytokines or using UMLILO IncRNA's to increase the production of ELR+ proinflammatory cytokines. The invention also provides for the use of UMLILO IncRNA inhibitors or UMLILO IncRNA's to modulate the expression of ERL+ proinflammatory cytokines.
    Type: Application
    Filed: December 14, 2018
    Publication date: November 7, 2019
    Inventors: Emiliano DALLA, Musa M. MHLANGA, Stephanie FANUCCHI, Youtaro SHIBAYAMA
  • SITE-SPECIFIC NUCLEASE SINGLE-CELL ASSAY TARGETING GENE REGULATORY ELEMENTS TO SILENCE GENE EXPRESSION
    Publication number: 20190112592
    Abstract: This invention relates to a single cell assay for determining the effect of chromosomal contact on the transcriptional activity of genes of interest in a cell and to methods of silencing gene expression in a cell by way of perturbing gene regulatory elements which are engaged in chromosomal contact.
    Type: Application
    Filed: November 19, 2018
    Publication date: April 18, 2019
    Inventors: Stephanie FANUCCHI, Youtaro SHIBAYAMA, Shaun BURD, Musa M. MHLANGA
  • Site-specific nuclease single-cell assay targeting gene regulatory elements to silence gene expression
    Patent number: 10167466
    Abstract: This invention relates to a single cell assay for determining the effect of chromosomal contact on the transcriptional activity of genes of interest in a cell and to methods of silencing gene expression in a cell by way of perturbing gene regulatory elements which are engaged in chromosomal contact.
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: January 1, 2019
    Assignee: CSIR
    Inventors: Stephanie Fanucchi, Youtaro Shibayama, Shaun Burd, Musa M. Mhlanga
  • IMMUNOMODULATION BY CONTROLLING ELR+ PROINFLAMMATORY CHEMOKINE LEVELS WITH THE LONG NON-CODING RNA UMLILO
    Publication number: 20170349898
    Abstract: The present invention relates to methods for modulating the production of ELR+ proinflammatory chemokines in a subject or a cell using either UMLILO IncRNA inhibitors to decrease production of ELR+ proinflammatory cytokines or using UMLILO IncRNA's to increase the production of ELR+ proinflammatory cytokines. The invention also provides for the use of UMLILO IncRNA inhibitors or UMLILO IncRNA's to modulate the expression of ERL+ proinflammatory cytokines.
    Type: Application
    Filed: December 18, 2015
    Publication date: December 7, 2017
    Applicant: CSIR
    Inventors: EMILIANO DALLA, MUSA M. MHLANGA, STEPHANIE FANUCCHI, YOUTARO SHIBAYAMA
  • Site-Specific Nuclease Single-Cell Assay Targeting Gene Regulatory Elements to Silence Gene Expression
    Publication number: 20160215280
    Abstract: This invention relates to a single cell assay for determining the effect of chromosomal contact on the transcriptional activity of genes of interest in a cell and to methods of silencing gene expression in a cell by way of perturbing gene regulatory elements which are engaged in chromosomal contact.
    Type: Application
    Filed: September 4, 2014
    Publication date: July 28, 2016
    Applicant: CSIR
    Inventors: Stephanie FANUCCHI, Youtaro SHIBAYAMA, Shaun BURD, Musa M. MHLANGA