Patents by Inventor Stephanie Hopkins

Stephanie Hopkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hedgehog inhibitors
    Patent number: 9174949
    Abstract: Described herein are compounds, pharmaceutical compositions and methods for the inhibition of Hedgehog signaling. Said compounds, pharmaceutical compositions and methods have utility in the treatment of human and veterinary disease and disorders.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: November 3, 2015
    Assignee: SELEXAGEN THERAPEUTICS, INC.
    Inventors: Jean-Michel Vernier, John May, Patrick O'Connor, William Ripka, Anthony Pinkerton, Pierre-Yves Bounaud, Stephanie Hopkins
  • RAF KINASE INHIBITORS
    Publication number: 20140221374
    Abstract: Described herein are compounds, pharmaceutical compositions and methods for the inhibition of RAF kinase mediated signaling. Said compounds, pharmaceutical compositions and methods have utility in the treatment of human disease and disorders.
    Type: Application
    Filed: March 16, 2012
    Publication date: August 7, 2014
    Applicant: Ruga Corporation
    Inventors: Jean-Michel Vernier, Stephanie Hopkins, Pierre-Yves Bounaud, Patrick O'Connor, David Matthews, Steve Bender
  • RAF KINASE INHIBITORS
    Publication number: 20130040983
    Abstract: Described herein are compounds, pharmaceutical compositions and methods for the inhibition of RAF kinae mediated signaling. Said compounds, pharmaceutical compositions and methods have utility in the treatment of human disease and disorders.
    Type: Application
    Filed: January 7, 2011
    Publication date: February 14, 2013
    Inventors: Jean-Michel Vernier, Patrick O'Connor, William Ripka, David Matthews, Anthony Pinkerton, Pierre-Yves Bounaud, Stephanie Hopkins
  • HEDGEHOG INHIBITORS
    Publication number: 20130012513
    Abstract: Described herein are compounds, pharmaceutical compositions and methods for the inhibition of Hedgehog signaling. Said compounds, pharmaceutical compositions and methods have utility in the treatment of human and veterinary disease and disorders.
    Type: Application
    Filed: January 6, 2011
    Publication date: January 10, 2013
    Inventors: Jean-Michel Vernier, John May, Patrick O'Connor, William Ripka, Anthony Pinkerton, Pierre-Yves Bounaud, Stephanie Hopkins
  • Fused ring heterocycle kinase modulators
    Patent number: 8268994
    Abstract: The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: August 11, 2009
    Date of Patent: September 18, 2012
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Pierre Bounaud, Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Stephanie Hopkins, Zhe Li, Ian McDonald, Paul A. Sprengeler, Ruo W. Steensma, Mark E. Wilson
  • Fused ring heterocycle kinase modulators
    Patent number: 8242280
    Abstract: The present invention provides fused ring heterocycles as kinase modulators, pharmaceutical compositions containing these modulators, and methods of using these modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: April 10, 2008
    Date of Patent: August 14, 2012
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Gavin Hirst, Stephanie Hopkins, Khanh Thi Tuong Nguyen, Richard Pracitto, Paul E. Sprengeler, Ruo W. Steensma
  • Substituted pyrrolopyridines and pyrazolopyridines as kinase modulators
    Patent number: 8158647
    Abstract: Provided herein are substituted pyrrolopyridine heterocycles and substituted pyrazolopyridine heterocycles, pharmaceutical compositions comprising said heterocycles and methods of using said heterocycles in the treatment of disease. The heterocycles disclosed herein function as kinase modulators and have utility in the treatment of diseases such as cancer, allergy, asthma, inflammation, obstructive airway disease, autoimmune diseases, metabolic disease, infection, CNS disease, brain tumor, obesity, asthma, hematological disorder, degenerative neural disease, cardiovascular disease, or disease associated with angiogenesis, neovascularization, or vasculogenesis.
    Type: Grant
    Filed: May 29, 2008
    Date of Patent: April 17, 2012
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: Jeffrey M. Blaney, Andreas Gosberg, Stefan N. Gradl, Gavin Hirst, Stephanie A. Hopkins, Paul A. Sprengeler, Ruo W. Steensma, Johnny Uy
  • Pyrimidinyl-thiophene kinase modulators
    Patent number: 7977481
    Abstract: The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: August 6, 2010
    Date of Patent: July 12, 2011
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Chixu Chen, Stefan N. Gradl, Stephanie Hopkins, Ruo W. Steensma, Masaki Tomimoto, Mark E. Wilson
  • Pyrimidinyl-Thiophene Kinase Modulators
    Publication number: 20100305128
    Abstract: The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: August 6, 2010
    Publication date: December 2, 2010
    Inventors: William D. Arnold, Chixu Chen, Stefan N. Gradl, Stephanie A. Hopkins, Ruo W. Steensma, Masaki Tomimoto, Mark E. Wilson
  • Pyrimidinyl-thiophene kinase modulators
    Patent number: 7803806
    Abstract: The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: September 28, 2010
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Chixu Chen, Stefan N. Gradl, Stephanie A. Hopkins, Ruo W. Steensma, Masaki Tomimoto, Mark E. Wilson
  • Pyrrolo-pyridine kinase modulators
    Patent number: 7709645
    Abstract: The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: May 4, 2010
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D Arnold, Pierre Bounaud, Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Stephanie Hopkins, Zhe Li, Ian McDonald, Paul A. Sprengeler, Ruo W. Steensma, Mark E. Wilson
  • Fused Ring Heterocycle Kinase Modulators
    Publication number: 20100036118
    Abstract: The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: August 11, 2009
    Publication date: February 11, 2010
    Inventors: William D. Arnold, Pierre Bounaud, Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Stephanie Hopkins, Zhe Li, Ian McDonald, Paul A. Sprengeler, Ruo W. Steensma, Mark E. Wilson
  • Fused ring heterocycle kinase modulators
    Patent number: 7626021
    Abstract: The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: December 1, 2009
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Pierre Bounaud, Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Stephanie Hopkins, Zhe Li, Ian McDonald, Paul A. Sprengeler, Ruo W. Steensma, Mark E. Wilson
  • PYRROLO-PYRIDINE KINASE MODULATIORS
    Publication number: 20090143352
    Abstract: The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: April 10, 2007
    Publication date: June 4, 2009
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: William D. Arnold, Pierre Bounaud, Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Stephanie Hopkins, Zhe Li, Ian McDonald, Paul A. Sprengeler, Ruo W. Steensma, Mark E. Wilson
  • Peptides which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, compositions and uses thereof
    Patent number: 7517855
    Abstract: The present invention relates generally to peptides, which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, methods of making peptides, which inhibit angiogenesis, cell migration, cell invasion and cell proliferation, pharmaceutical compositions of these peptides and methods of using these peptides and pharmaceutical compositions of these peptides to treat diseases associated with aberrant vascularization.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: April 14, 2009
    Assignee: Attenuon, LLC
    Inventors: Robert J. Ternansky, Stephanie A. Hopkins, Won Hyung Yoon, Amy L. Allan, Patricia L. Gladstone, Sean M. O'Hare, Fernando Donate, Andrew Mazar, Graham Parry, Marian Plunkett
  • SUBSTITUTED PYRROLOPYRIDINES AND PYRAZOLOPYRIDINES AS KINASE MODULATORS
    Publication number: 20090005356
    Abstract: Provided herein are substituted pyrrolopyridine heterocycles and substituted pyrazolopyridine heterocycles, pharmaceutical compositions comprising said heterocycles and methods of using said heterocycles in the treatment of disease. The heterocycles disclosed herein function as kinase modulators and have utility in the treatment of diseases such as cancer, allergy, asthma, inflammation, obstructive airway disease, autoimmune diseases, metabolic disease, infection, CNS disease, brain tumor, obesity, asthma, hematological disorder, degenerative neural disease, cardiovascular disease, or disease associated with angiogenesis, neovascularization, or vasculogenesis.
    Type: Application
    Filed: May 29, 2008
    Publication date: January 1, 2009
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: Jeffrey M. Blaney, Andreas Gosberg, Stefan N. Gradl, Gavin Hirst, Stephanie A. Hopkins, Paul A. Sprengeler, Ruo W. Steensma, Johnny Uy
  • FUSED RING HETEROCYCLE KINASE MODULATORS
    Publication number: 20080261921
    Abstract: The present invention provides fused ring heterocycles as kinase modulators, pharmaceutical compositions containing these modulators, and methods of using these modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: April 10, 2008
    Publication date: October 23, 2008
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan N. Gradl, Gavin Hirst, Stephanie Hopkins, Khanh Thi Tuong Nguyen, Richard Pracitto, Paul E. Sprengeler, Ruo W. Steensma
  • FUSED RING HETEROCYCLE KINASE MODULATORS
    Publication number: 20070287711
    Abstract: The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: April 10, 2007
    Publication date: December 13, 2007
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: William Arnold, Pierre Bounaud, Chixu Chen, Brian Eastman, Andreas Gosberg, Stefan Gradl, Stephanie Hopkins, Zhe Li, Ian McDonald, Paul Sprengeler, Ruo Steensma, Mark Wilson
  • Pyrazolothiazole Protein Kinase Modulators
    Publication number: 20070173488
    Abstract: The present invention provides pyrazolothiazole kinase modulators, methods of treating certain disease states, such as cancer, and pharmaceutical composition thereof.
    Type: Application
    Filed: November 16, 2006
    Publication date: July 26, 2007
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: Pierre-Yves Bounaud, Stephanie Hopkins, Elizabeth Jefferson, Mark Wilson, Melissa Wong, Toufike Kanouni
  • PYRIMIDINYL-THIOPHENE KINASE MODULATORS
    Publication number: 20070117800
    Abstract: The present invention provides novel pyrimidinyl-thiophene kinase modulators and methods of using the novel pyrimidinyl-thiophene kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: November 2, 2006
    Publication date: May 24, 2007
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: William Arnold, Chixu Chen, Stefan Gradl, Stephanie Hopkins, Ruo Steensma, Masaki Tomimoto, Mark Wilson