Patents by Inventor Stephanie Jane Clegg

Stephanie Jane Clegg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIGEN BINDING PROTEINS
    Publication number: 20230137032
    Abstract: The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
    Type: Application
    Filed: July 12, 2022
    Publication date: May 4, 2023
    Inventors: Paul ALGATE, Stephanie Jane CLEGG, Jennifer L. CRAIGEN, Paul Andrew HAMBLIN, Alan Peter LEWIS, Patrick MAYES, Radha Shah PARMAR, Trevor Anthony Kenneth WATTAM
  • Antigen binding proteins
    Patent number: 11419945
    Abstract: The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: August 23, 2022
    Assignee: GLAXO GROUP LIMITED
    Inventors: Paul Algate, Stephanie Jane Clegg, Jennifer L. Craigen, Paul Andrew Hamblin, Alan Peter Lewis, Patrick Mayes, Radha Shah Parmar, Trevor Anthony Kenneth Wattam
  • ANTIGEN BINDING PROTEINS
    Publication number: 20200197529
    Abstract: The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
    Type: Application
    Filed: March 11, 2020
    Publication date: June 25, 2020
    Inventors: Paul Algate, Stephanie Jane Clegg, Jennifer L. Craigen, Paul Andrew Hamblin, Alan Peter Lewis, Patrick Mayes, Radha Shah Parmar, Trevor Anthony Kenneth Wattam
  • ANTIGEN BINDING PROTEINS
    Publication number: 20180147293
    Abstract: The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
    Type: Application
    Filed: December 1, 2017
    Publication date: May 31, 2018
    Inventors: PAUL ALGATE, STEPHANIE JANE CLEGG, JENNIFER L. CRAIGEN, PAUL ANDREW HAMBLIN, ALAN PETER LEWIS, PATRICK MAYES, RADHA SHAH PARMAR, TREVOR ANTHONY KENNETH WATTAM
  • ANTIGEN-BINDING CONSTRUCTS
    Publication number: 20160207993
    Abstract: The invention relates to antigen-binding constructs comprising a protein scaffold which are linked to one or more epitope-binding domains wherein the antigen-binding construct has at least two antigen binding sites at least one of which is from an epitope binding domain and at least one of which is from a paired VH/VL domain, methods of making such constructs and uses thereof.
    Type: Application
    Filed: June 15, 2015
    Publication date: July 21, 2016
    Inventors: Claire ASHMAN, Thil Batuwangala, Michael Neil Burden, Stephanie Jane Clegg, Rudolf Maria De Wildt, Jonathan Henry Ellis, Paul Andrew Hamblin, Farhana Hussain, Laurent Jespers, Alan Lewis, Martin Anibal Orecchia, Radha Shah, Michael Steward
  • ANTIGEN BINDING PROTEINS
    Publication number: 20160193358
    Abstract: The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
    Type: Application
    Filed: December 18, 2015
    Publication date: July 7, 2016
    Inventors: Paul Algate, Stephanie Jane Clegg, Jennifer L. Craigen, Paul Andrew Hamblin, Alan Peter Lewis, Patrick Mayes, Radha Shah Parmar, Trevor Anthony Kenneth Wattam
  • B cell maturation antigen (BCMA) binding proteins
    Patent number: 9273141
    Abstract: The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: March 1, 2016
    Assignee: Glaxo Group Limited
    Inventors: Paul Algate, Stephanie Jane Clegg, Jennifer L. Craigen, Paul Andrew Hamblin, Alan Peter Lewis, Patrick Mayes, Radha Shah Parmar, Trevor Anthony Kenneth Wattam
  • Compounds
    Patent number: 8828384
    Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.
    Type: Grant
    Filed: June 26, 2013
    Date of Patent: September 9, 2014
    Assignee: GlaxoSmithKline LLC
    Inventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Pual Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
  • BCMA (CD269/TNFRSF17) - BINDING PROTEINS
    Publication number: 20140105915
    Abstract: The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
    Type: Application
    Filed: May 24, 2012
    Publication date: April 17, 2014
    Applicant: Glaxo Group Limited
    Inventors: Paul Algate, Stephanie Jane Clegg, Jennifer L. Craigen, Paul Andrew Hamblin, Alan Peter Lewis, Patrick Mayes, Radha Shah Parmar, Trevor Anthony Kenneth Wattam
  • NOVEL COMPOUNDS
    Publication number: 20140010807
    Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.
    Type: Application
    Filed: June 26, 2013
    Publication date: January 9, 2014
    Inventors: Stephanie Jane CLEGG, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
  • IMMUNOGLOBULINS
    Publication number: 20130287781
    Abstract: The present invention relates to antibodies to NOGO, pharmaceutical formulations containing such antibodies and the use of such antibodies in the treatment and/or prophylaxis of neurological diseases/disorder.
    Type: Application
    Filed: January 28, 2013
    Publication date: October 31, 2013
    Inventors: Stephanie Jane CLEGG, Jonathan Henry Ellis, Volker Germaschewski, Paul Andrew Hamblin, George Kopsidas, Ruth McAdam, Rabiner Kumar Prinjha
  • Compounds
    Patent number: 8496932
    Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: July 30, 2013
    Assignee: GlaxoSmithKline
    Inventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
  • Immunoglobulins
    Patent number: 8362208
    Abstract: The present invention relates to antibodies to NOGO, pharmaceutical formulations containing them and to the use of such antibodies in the treatment and/or prophylaxis of neurological diseases/disorder.
    Type: Grant
    Filed: December 14, 2006
    Date of Patent: January 29, 2013
    Assignee: Glaxo Group Limited
    Inventors: Stephanie Jane Clegg, Jonathan Henry Ellis, Volker Germaschewski, Paul Andrew Hamblin, George Kopsidas, Ruth McAdam, Rabinder Kumar Prinjha
  • NOVEL USES
    Publication number: 20120315267
    Abstract: The present invention relates to antibodies which multiple antigen specificities and their use in treating human diseases
    Type: Application
    Filed: February 9, 2011
    Publication date: December 13, 2012
    Applicant: GLAXOSMITHKLINE LLC
    Inventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan Henry Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan Peter Lewis, John Richard White
  • NOVEL COMPOUNDS
    Publication number: 20110229475
    Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.
    Type: Application
    Filed: April 16, 2008
    Publication date: September 22, 2011
    Inventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
  • NOVEL COMPOUNDS
    Publication number: 20110105724
    Abstract: The present invention relates to neutralizing antibodies (immunoglobulins) which are specific for human IL-8 and bind to as well as neutralize human IL-8.
    Type: Application
    Filed: August 15, 2008
    Publication date: May 5, 2011
    Inventors: Stephanie Jane Clegg, Jonathan H. Ellis, Paul Andrew Hamblin, Karen Fran Kozarsky, Jui-Lan Su, Deborah Ann Welham
  • ANTIGEN-BINDING CONSTRUCTS
    Publication number: 20110008345
    Abstract: The invention relates to antigen-binding constructs comprising a protein scaffold which are linked to one or more epitope-binding domains wherein the antigen-binding construct has at least two antigen binding sites at least one of which is from an epitope binding domain and at least one of which is from a paired VH/VL domain, methods of making such constructs and uses thereof.
    Type: Application
    Filed: November 28, 2008
    Publication date: January 13, 2011
    Inventors: Claire Ashman, Thil Batuwangala, Michael Neil Burden, Stephanie Jane Clegg, Rudolf Maria De Wildt, Jonathan Henry Ellis, Paul Andrew Hamblin, Farhana Hussain, Laurent Jespers, Alan Lewis, Martin Anibal Orecchia, Radha Shah, Michael Steward
  • IMMUNOGLOBULINS
    Publication number: 20100221260
    Abstract: The present invention relates to antibodies to NOGO, pharmaceutical formulations containing them and to the use of such antibodies in the treatment and/or prophylaxis of neurological diseases/disorder.
    Type: Application
    Filed: December 14, 2006
    Publication date: September 2, 2010
    Inventors: Stephanie Jane Clegg, Jonathan Henry Ellis, Volker Germaschewski, Paul Andrew Hamblin, George Kopsidas, Ruth McAdam, Rabinder Kumar Prinjha
  • ANTIGEN-BINDING CONSTRUCTS
    Publication number: 20090148905
    Abstract: The invention relates to antigen-binding constructs comprising a protein scaffold which are linked to one or more epitope-binding domains wherein the antigen-binding construct has at least two antigen binding sites at least one of which is from an epitope binding domain and at least one of which is from a paired VH/VL domain, methods of making such constructs and uses thereof.
    Type: Application
    Filed: November 28, 2008
    Publication date: June 11, 2009
    Inventors: Claire ASHMAN, Thil Batuwangala, Michael Neil Burden, Stephanie Jane Clegg, Rudolf Maria De Wildt, Jonathan Henry Ellis, Paul Andrew Hamblin, Farhana Hussain, Laurent Jespers, Alan Lewis, Martin Anibal Orecchia, Radha Shah, Michael Steward
  • NOVEL COMPOUNDS
    Publication number: 20080262203
    Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.
    Type: Application
    Filed: April 16, 2008
    Publication date: October 23, 2008
    Inventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White