Patents by Inventor Stephanie LORAIN

Stephanie LORAIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combined therapy for duchenne muscular dystrophy
    Patent number: 10471089
    Abstract: The present invention relates to the combined use of antisense oligonucleotides and viral vectors for the treatment of Duchenne muscular dystrophy.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: November 12, 2019
    Assignees: ASSOCIATION INSTITUT DE MYOLOGIE, SORBONNE UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Stephanie Lorain, Thomas Voit, Matthew Wood, Graham McClorey
  • COMBINED THERAPY FOR DUCHENNE MUSCULAR DYSTROPHY
    Publication number: 20180169130
    Abstract: The present invention relates to the combined use of antisense oligonucleotides and viral vectors for the treatment of Duchenne muscular dystrophy.
    Type: Application
    Filed: June 10, 2016
    Publication date: June 21, 2018
    Inventors: Stephanie LORAIN, Thomas VOIT, Matthew WOOD, Graham MCCLOREY
  • Nucleic acid molecules and methods for exchanging exon(s) by transsplicing
    Patent number: 9303078
    Abstract: The present invention provided methods and compositions for generating novel nucleic acid molecules through targeted spliceosome mediated simple or double trans-splicing. The compositions of the invention include pre-trans-splicing molecules (PTMs) designed to interact with a target precursor messenger RNA molecule (target pre-mRNA) and to mediate a simple or double trans-splicing reaction resulting in the generation of a novel chimeric RNA molecule (Chimeric RNA).
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: April 5, 2016
    Assignees: ASSOCIATION INSTITUT DE MYOLOGIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE PIERRE ET MARIE CURRIE (PARIS 6)
    Inventors: Luis Garcia, Stéphanie Lorain
  • NUCLEIC ACID MOLECULES AND METHODS FOR EXCHANGING EXON(S) BY TRANSSPLICING
    Publication number: 20130065948
    Abstract: The present invention provides methods and compositions for generating novel nucleic acid molecules through targeted spliceosome mediated simple or double trans-splicing. The compositions of the invention include pre-trans-splicing molecules (PTMs) designed to interact with a target precursor messenger RNA molecule (target pre-mRNA) and to mediate a simple or double trans-splicing reaction resulting in the generation of a novel chimeric RNA molecule (chimeric RNA).
    Type: Application
    Filed: October 8, 2010
    Publication date: March 14, 2013
    Applicants: ASSOCIATION INSTITUT DE MYOLOGIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
    Inventors: Luis GARCIA, Stephanie LORAIN
  • NUCLEIC ACID MOLECULES AND METHODS FOR EXCHANGING EXON(S) BY TRANSSPLICING
    Publication number: 20120245220
    Abstract: The present invention provided methods and compositions for generating novel nucleic acid molecules through targeted spliceosome mediated simple or double trans-splicing. The compositions of the invention include pre-trans-splicing molecules (PTMs) designed to interact with a target precursor messenger RNA molecule (target pre-mRNA) and to mediate a simple or double trans-splicing reaction resulting in the generation of a novel chimeric RNA molecule (Chimeric RNA).
    Type: Application
    Filed: October 8, 2010
    Publication date: September 27, 2012
    Applicants: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), ASSOCIATION INSTITUT DE MYOLOGIE
    Inventors: Luis Garcia, Stéphanie Lorain