Patents by Inventor Stephanie Marie Truhlar

Stephanie Marie Truhlar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bispecific antibodies targeting immune checkpoints
    Patent number: 11939381
    Abstract: The present invention relates to bispecific antibodies that antagonize human PD-1 and agonize human CD137, and may be useful for treating solid and hematological tumors alone and in combination with chemotherapy and ionizing radiation.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: March 26, 2024
    Assignee: Eli Lilly and Company
    Inventors: Stephen J. Demarest, Yiqing Feng, Juqun Shen, Yang Shen, Stephanie Marie Truhlar
  • TIGIT AND PD-1/TIGIT-BINDING MOLECULES
    Publication number: 20220227860
    Abstract: The present invention relates to polypeptide molecules that bind to human TIGIT, and to polypeptide molecules that bind to human PD-1 and human TIGIT, and are useful for treating solid tumors, alone and in combination with chemotherapy and/or ionizing radiation.
    Type: Application
    Filed: May 22, 2020
    Publication date: July 21, 2022
    Inventors: Yiqing FENG, Naresh KUMAR, James David PANCOOK, Stephanie Marie TRUHLAR, Yang ZHAO
  • BISPECIFIC ANTIBODIES TARGETING IMMUNE CHECKPOINTS
    Publication number: 20210292416
    Abstract: The present invention relates to bispecific antibodies that antagonize human PD-1 and agonize human CD137, and may be useful for treating solid and hematological tumors alone and in combination with chemotherapy and ionizing radiation.
    Type: Application
    Filed: July 12, 2019
    Publication date: September 23, 2021
    Inventors: Stephen J. DEMAREST, Yiqing FENG, Juqun SHEN, Yang SHEN, Stephanie Marie TRUHLAR
  • DNA molecules encoding anti-IL-33 antibodies
    Patent number: 10913793
    Abstract: Antibodies which bind and neutralize human IL-33, and methods of using same, are provided, said antibodies are useful as agents for treating conditions associated with allergic disease including treating atopic dermatitis.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: February 9, 2021
    Assignee: Eli Lilly and Company
    Inventors: Robert Jan Benschop, Julian Davies, Angela Jeannine Okragly, Chetankumar Natvarlal Patel, Stephanie Marie Truhlar
  • ANTI-IL-33 ANTIBODIES AND USES THEREOF
    Publication number: 20200048340
    Abstract: Antibodies which bind and neutralize human IL-33, and methods of using same, are provided, said antibodies are useful as agents for treating conditions associated with allergic disease including treating atopic dermatitis.
    Type: Application
    Filed: October 25, 2019
    Publication date: February 13, 2020
    Inventors: Robert Jan Benschop, Julian Davies, Angela Jeannine Okragly, Chetankumar Natvarlal Patel, Stephanie Marie Truhlar
  • Anti-IL-33 antibodies and uses thereof for disease treatment
    Patent number: 10501536
    Abstract: Antibodies which bind and neutralize human IL-33, and methods of using same, are provided, said antibodies are useful as agents for treating conditions associated with allergic disease including treating atopic dermatitis.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: December 10, 2019
    Assignee: Eli Lilly and Company
    Inventors: Robert Jan Benschop, Julian Davies, Angela Jeannine Okragly, Chetankumar Natvarlal Patel, Stephanie Marie Truhlar
  • PD-1 agonist antibodies and uses thereof
    Patent number: 10493148
    Abstract: The present invention relates to anti-human PD-1 agonist antibodies, and uses thereof for treating autoimmune disorders such as rheumatoid arthritis or for decreasing rejection of transplanted cells and/or tissues.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: December 3, 2019
    Assignee: Eli Lilly and Company
    Inventors: Pia Pauliina Yachi, Qing Chai, Yiqing Feng, Kristin Paige Newburn, Stephanie Marie Truhlar, Petra Verdino
  • PD-1 AGONIST ANTIBODIES AND USES THEREOF
    Publication number: 20190270818
    Abstract: The present invention relates to anti-human PD-1 agonist antibodies, and uses thereof for treating autoimmune disorders such as rheumatoid arthritis or for decreasing rejection of transplanted cells and/or tissues.
    Type: Application
    Filed: February 22, 2019
    Publication date: September 5, 2019
    Inventors: Pia Pauliina Yachi, Qing Chai, Yiqing Feng, Kristin Paige Newburn, Stephanie Marie Truhlar, Petra Verdino